We have already discussed in detail the exceptional properties of pyrroloquinoline quinone (PQQ):
It is an ultra-powerful antioxidant, up to 5,000 times more effective than vitamin C.
It is the only nutrient capable of generating new mitochondria – up to 20% more, in existing – even aging - cells.
It uniquely ensures protection for mitochondrial DNA, which is particularly exposed and vulnerable to oxidative stress.
¤ It has also been shown that PQQ has developed a particular synergy with the two nutrients scientifically-demonstrated as most effective at optimising the function of existing mitochondria: R-lipoic acid and acetyl-L-carnitine. It now appears that concurrent use of coenzyme Q10 significantly enhances the benefits obtained from taking PQQ. This is not surprising given that CoQ10’s principal role is to provide mitochondrial fuel, to promote cellular respiration and increase production of adenosine triphosphate (ATP).
¤ In particular, recent studies demonstrate better cardiovascular and cognitive performance when PQQ and CoQ10 are taken in combination, compared with when they are taken separately. Again, this is unsurprising as the heart and brain are by far the most energy-consuming organs.
¤ A Japanese study conducted in 2007 showed that supplementing with 20mg PQQ a day improved memory, attention and cognitive function; the performance of a supplemented group was twice that of a placebo group. The addition of 300mg CoQ10 further enhanced performance in memory tests. Conclusion: mental aptitude and quality of life can be improved in older people, and this treatment constitutes an aid to preventing the deterioration of cognitive function in elderly individuals.
¤ Another study showed that PQQ was also more active when combined with antioxidants, and that when taken alongside CoQ10, neurodegenerative parameters improved and the nerve growth factor neurotrophin was stimulated. Similarly, the PQQ-CoQ10 combination slowed down cerebral degeneration and reduced amyloid plaque formation (one of the likely causes of Alzheimer’s disease and dementia) and possibly also cerebral atrophy (age-related shrinking of the brain).
In addition to PQQ and CoQ10, you may also be interested in other powerful antioxidants for combatting age-related cellular damage. One such molecule is , the natural antioxidant found in grapes and red wine. For optimal efficacy, this protective compound can also be combined with other antioxidants such as in the synergistic formulation .
Taken together, PQQ and CoQ10 improve antioxidant status and mitochondrial health via complementary mechanisms. They also provide multi-faceted support for cardiovascular and cerebral function. They improve mental condition and quality of life in elderly patients and may be beneficial in delaying or preventing cognitive decline in middle-aged individuals.
Adults. Take one or two capsules a day, preferably with a meal containing a little fat.
Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet. Keep out of childrens' reach. Store away from direct light, heat and humidity. As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.