Benfotiamine is the most potent of the allithiamines, a unique class of thiamine derivatives (vitamin B1) with a highly specific structure which enables them to pass easily through cell membranes. As such, it is much better absorbed (5-25 times better!) than thiamine and remains in the body for considerably longer. Benfotiamine is therefore much more effective at correcting traditional vitamin B1 deficiency (beri beri, alcoholism) than thiamine itself. However, its main benefits lie in a different area: Benfotiamine is remarkably effective at inhibiting the formation of AGE - Advanced Glycation Endproducts. It increases threefold the concentration of the endogenous enzyme transketolase which breaks down AGE and converts them into harmless compounds. AGE's main targets are the nerves, blood vessels, eyes and kidneys, and since diabetics produce AGE in excess, this discovery is particularly significant for them. Regular supplementation with benfotiamine can significantly improve their quality of life as has been shown in controlled studies. Of course, benfotiamine, like carnosine or lipoic acid, is a valuable weapon for anyone wish to fight the inevitable process of tissue ‘caramelisation'. Glycation (caramelisation of cells), together with oxidation, is a basic mechanism of the biochemical breakdown associated with ageing, though the compounds capable of controlling it are fewer in number and less well-known. Benfotiamine is a remarkable AGE inhibitor, tested successfully not just in vitro and on animals, but actually on humans.

Recommended use: Take two to four vegicaps a day at mealtimes or as advised by your therapist.