Lutein, zeaxanthin and its stereo-isomer, mesozeaxanthin, principally make up the pigment that covers the macular area of the eye. These three antioxidant carotenoids, present in equal amounts in the centre of the retina, filter blue light and protect the photoreceptors from oxidative damage. Macular pigment density varies from one person to another, but diminishes as we get older.

¤ Mesozeaxanthin is produced in the retina from lutein. As we age, this conversion becomes less effective and levels of mesozeaxanthin fall. Studies have shown that :

- levels of lutein, zeaxanthin and mesozeaxanthin are lower in the eyes of individuals with age-related macular degeneration ;
- supplementing with lutein, zeaxanthhin and mesozeaxanthin boosts macular pigment density and therefore increases protection for the eyes against oxidative damage ;
- we cannot get mesozeaxanthin from the diet but macular pigment density increases with supplementation. ;
- supplementing with lutein and zeaxanthin protects against cataract development and progression ;
- supplementing with lutein and zeaxanthin may improve vision mechanisms in individuals with early-stage age-related macular degeneration. Scientists believe that those at higher risk of developing AMD or cataract should increase their lutein, zeaxanthin and mesozeaxanthin intake accordingly.

Macula Plus is boosted by the addition of cyanidine-3-glycoside (C3G), a purple pigment from the flavonoid family, as well as by the carotenoid astaxanthin.

¤ C3G enhances night vision by encouraging regeneration of rhodopsin, a pigment present in the eyes' photoreceptor cells. C3G has antioxidant properties and thus helps protect the eyes against free radical attack.

¤ Astaxanthin helps relieve tired eyes (caused, in particular, by looking at a computer screen). It also boosts antioxidant defences and provides additional protection against inflammatory changes that can aggravate AMD.

adults. Take one vegetarian capsule a day with a meal, or as advised by your therapist.