Horse Chestnut extract is standardized in Escine which is the best existing natural therapy for varicose veins.
Several million westerners suffer from varix a cosmetic problem which is often the early symptom of serious cardiovascular problems. Horse Chestnut extract treats varicose veins, chronic veinous insufficiency and leg edemas. Its active ingredient, Escine, reduces the number and the diameter of the capillary membrane pores,  thus reducing fluid leaks to surrounding tissue, which improves blood circulation in the veins and reduces unaesthetic swelling of the capillary leg vessels.
A study published in The Lancet (Feb 3, 1996; vol.347 pp. 292-294) showed an average leg fluid reduction of 43.8 ml  after 12 weeks of use. The action of Horse Chestnut extract on the edema is strong and durable. One considers that it is 600 times more powerful than Rutin's (another natural therapy for the same condition) !