Natural Skin Formula is the only formulation to provide - in one product - all the structural elements necessary (collagen, elastin, ceramides, hyaluronic acid) to rejuvenate the skin, plus ingredients which stimulate their renewal and two antioxidants, resveratrol and GliSODin, known for their protective properties.

¤ Hyaluronic acid, which can retain over a thousand times its weight in water, is essential for maintaining hydration of skin tissues, but levels decrease as we age. Supplementing with hyaluronic acid encourages the proliferation of fibroblasts, the cells responsible for producing elastin and collagen fibres. Studies have shown that when taken orally, low molecular weight hyaluronic acid is well absorbed by the body and that it :

• improves skin hydration and appearance ;
• accelerates healing of skin wounds.

¤ Collagen and elastin fibres are responsible for the cohesion, strength, elasticity and firmness of skin tissues. As we get older, they diminish; wrinkles appear and the contours of the face start to sag. Supplementing with type II collagen and elastin boosts concentration of these fibres and stimulates their renewal, reducing wrinkles and increasing hydration of the outer layers of the epidermis.

¤ Hydroxyproline is essential for the formation of collagen and elastin. When women with dry skin supplement with hydroxyproline, their facial skin is better hydrated, softer and wrinkles diminish.

¤ Ceramides, rich in glycosphingolipids, account for between 40 and 60 % of the lipid content of the stratum corneum, the outermost layer of the epidermis. As ceramide levels decrease with age, fine lines and wrinkles appear. Supplementation with wheat ceramides improves skin dryness and irritation ; the texture, softness and exfoliation of the skin all improve.

¤ Silicon is vital for optimal production of collagen and elastin. Women with signs of premature skin ageing from sun exposure given silicon supplements benefit from a decrease in wrinkles and an improvement in skin elasticity and roughness.

¤ Biotin, or vitamin B8, is also essential for skin health and, at the dose contained in Natural Skin Formula, has specific structural benefits.

¤ Resveratrol, extracted from Polygonum cuspidatum, is a polyphenolic compound from the flavonoid family

• known for its powerful antioxidant activity, it boosts the body’s antioxidant defences and scavenges free radicals before they can cause damage ;
• scientific research has shown that resveratrol activates the sirtuin (silent information regulator) genes associated with the prevention of ageing. In the skin, the sirtuin genes are found in the keratinocytes and fibroblasts of the dermis and epidermis. In vitro, stimulation of expression of these genes in skin cells led to a slowing down of the ageing process.

¤ GliSODin® is a natural superoxide dismutase (SOD) extracted from a variety of melon which is then bound to a wheat protein, gliadin, in order to increase its bioavailability. It boosts the pool of endogenous antioxidant enzymes and protects the skin from oxidative stress-induced skin damage. A number of studies have demonstrated that GliSODin® supplementation delays the appearance, and reduces the intensity, of erythema caused by UV exposure, even in fair-skinned subjects.

3 vegetarian capsules contain:

hyaluronic acid (from 100 mg of sodium hyaluronate also containing 15 to 20 % hydrolysed proteins and 10 to 20 % polysaccharides)	60 mg
Hydrolysed collagen type II	300 mg
Resveratrol (250 mg Polygonum cuspidatum extract 25 % resveratrol)	62,5 mg
Ceramides (from 24 mg wheat ceramides)	12 mg
GliSODin® (melon extract riche in superoxide dismutase, wheat gliadin)	60 mg
L-hydroxyproline	100 mg
Elastin (marine origin hydrolysate)	30 mg
D-biotin	10 mg
Silicon (bamboo extract 75 %)	25 mg
Excipients : magnesium stearate (E572), maltodextrin, silicon dioxide (E551). Attention : contains gluten. GliSODin® is a registered trademark and patented product (international patents WO 9621462 and WO 9935247) of Isocell SA.

Take one vegetarian capsule with each of your three main meals.