Originating from South Asia, Curcuma, or turmeric, is a perennial herbaceous plant and a member of the ginger family. It is particularly valued for its rhizomes (the underground parts) from which the yellow-orange spice is obtained. Though the spice is primarily known as a culinary ingredient, Curcuma also has a number of health benefits.

Fisetin 500 mg can either be used as a once a year, in a three-monthly treatment, or taken continuously, according to your needs. Tablets should be taken at mealtimes. Based on an animal study which produced extraordinary results, the dose selected was determined using the usual principle of dose conversion from animal to human (23). It constitutes a more powerful alternative to the already well-known formulation Senolytic Complex.

It should be noted that curcumin inhibits the glucuronoconjugation of fisetin and thus its bioavailability (by a factor of 30 according to some studies). DHA, however, acts in synergy with fisetin to reduce bone resorption. Bioflavonoids such as pycnogenol and quercetin are mutually reinforcing and it is therefore equally appropriate to combine them.

Attention: fisetin should not be taken alongside vitamin K antagonists, a widely prescribed class of anticoagulant drugs (24).

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