- Produced in Europe
- Helps regenerate and revitalise
- Convenient form (capsules)
- Supports the body through the change in seasons
- Precise dosage: standardised to 4% 10-HDA
Royal jelly is one of the richest substances found in Nature. As the seasons change, its exceptional content in rare nutrients makes it invaluable for effortlessly overcoming bouts of fatigue and finding new energy.
It is produced from a very sweet, whitish substance secreted by worker bees between their fourth and fifteenth day of life. It is the sole source of nutrition for larvae destined to become queen bees, and for adult queens once they leave the colony.
Royal jelly is considered an exceptional substance because of its rich content in essential nutrients. The jelly is a kind of thick, whitish paste with a faint smell but a hot, acidic taste which makes it particularly difficult to swallow in its fresh, non-lyophilised (non-freeze-dried) form (1).
In particular, it helps to:
The chemical compounds found in royal jelly are quite extraordinary, comprising a wide variety of carbohydrates, lipids and proteins. According to the scientific literature, however, it is the fatty acid 10HDA – the content of which varies between 3% and 5% - which is the most active compound.
10%-20% of royal jelly is made up of carbohydrates, the main ones being fructose and glucose, which account for around 90% of total carbohydrates. It is not uncommon to also find galactose, maltose, trehalose, turanose and palatinose (2).
Proteins are a major constituent of royal jelly. Free amino acids (especially proline, lysine, glutamine and glutamic acid) are present in significant quantities (3-4), as are remarkable proteins called Major Royal Jelly Proteins (MRJP).
Produced by the bees’ glands, these rare proteins belong to the family of apalbumins (5) and play a role in the function of the bees’ cognitive system. Royal jelly is also the only known source of an anti-microbial protein called royalisin (6).
Last but not least are the jelleins which are composed of 8-9 amino acids.
Royal jelly does not contain large quantities of lipids but those it does contain are of exceptional quality. The most prominent fatty acid is 10-hydroxy-2-decenoic acid (10H2DA), a quite remarkable compound. There is also gluconic acid (24 %), 10HDA (22 %) and various dicarboxylic acids (5 %) (7).
Unlike the majority of animal and plant-source fatty acids, those in royal jelly are short-chain (8-10 carbon atoms), recognised for their beneficial effects on the gut mucosa.
Royal jelly contains a number of vitamins, particularly all the B group vitamins. It also contains several minerals including potassium, calcium, magnesium, zinc, iron and copper.
Royal jelly is the sole source of nutrition for queen bees and larvae in the first days of life, and is thus particularly rare. Fortunately, a technique has been developed in recent years to make it more accessible.Producing royal jelly is a painstaking task which requires great patience on the part of the apiarist. A number of fundamental conditions are required:
The royal jelly offered by SuperSmart is freeze-dried and encapsulated using a modern technique which leaves its precious components unchanged. This process results in it losing almost two-thirds of its weight in water: 100mg of freeze-dried jelly is equivalent to around 300mg of fresh jelly.
Royal jelly’s mechanisms of action come from its composition and exceptional diversity. More powerful than honey (8), its antioxidant effects are believed to be comparable to those of vitamins C and E, as a result of its high peptide and free amino acid content (9).
Royal jelly is considered a tonic in traditional Chinese medicine, while in Eastern Europe, it is regarded as an excellent adaptogen (a substance which increases the body’s resistance to stress).
Like honey and propolis, it has been used by humans since antiquity. Multiple traces have been found of associations between humans of the Neolithic age and wild bees (10), long before apiculture was created concurrently by various civilisations, such as the Maya or ancient Rome, around 2400 BC.
Some believe its potential benefits for human health are based on the effects it induces in larvae: it is royal jelly which is responsible for the development of the queen’s reproductive organs and which accelerates her emergence from her cell (15 days for the queen compared with 21 for a worker bee). The exceptional fertility and lifespan enjoyed by the queen bee is thus due to royal jelly.
There is no need to refrigerate freeze-dried royal jelly.
Everyone can benefit from royal jelly, but it may be particularly useful for sportspeople, pregnant women, the over-40s, delicate individuals and those suffering from fatigue or recurrent illness.
The royal jelly sold by SuperSmart offers at least three key advantages:
A dose of 2-3 capsules a day is recommended as a course of treatment that can be repeated several times a year if required.
It is usually taken before breakfast, for between four and six weeks.
This product should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. It’s important to follow the directions for use, the recommended daily dose and the ‘use-by’ date. It is not recommended for women who are pregnant or breastfeeding, or for children under 15. Keep out of reach of young children. Store in a cool, dry place.
1. Krell R. Value Sadded Products from Beekeeping, Numéro 124. Food and Agriculture Organization;1996.409p.
2. Sesta G. Determination of sugars in royal jelly by HPLC. Apidologie. 2006 Jan;37(1):84– 90.
3. Sabatini AG, Marcazzan GL, Caboni MF, Bogdanov S, Almeida S Muradian Lb. Quality and standardisation of royal jelly. J ApiProduct ApiMedical Sci.2009;1(1):1–6.
4. Boselli E, Caboni MF, Sabatini AG, Marcazzan GL, Lercker G. Determination and changes of free amino acids in royal jelly during storage. Apidologie. 2003 Mar;34(2):129–37.
5. Scarselli R, Donadio E, Giuffrida MG, Fortunato D, Conti A, Balestreri E, et al. Towards royal jelly proteome.PROTEOMICS.2005 Feb 1;5(3):769–76.
6. Fujiwara S, Imai J, Fujiwara M, Yaeshima T, Kawashima T, Kobayashi K. A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin.JBiolChem.1990Jul5;265(19):11333–7.
7. Ramadan MF, AlSGhamdi A. Bioactive compounds and healthS promoting properties of royal jelly: A review. J FunctFoods.2012 Jan;4(1):39–52.
8. Nagai T, Sakai M, Inoue R, Inoue H, Suzuki N. Antioxidative activities of some commercially honeys, royal jelly, and propolis. Food Chem. 2001 Nov;75(2):237–40.
9. Guo H, Kouzuma Y, Yonekura M. Isolation and Properties of Antioxidative Peptides from WaterS Soluble Royal Jelly Protein Hydrolysate. Food Sci Technol Res. 2005;11(2):222–30
10. Chauvin R, editor. Traité de biologie de l’abeille. Paris: Masson et Cie; 1968. 152p.
|Daily dose: 3 capsules
Number of doses per pack: 30
|3:1 organic, freeze-dried royal jelly standardised to 4% 10-HDA||300 mg|
|Other ingredients: acacia gum, rice bran.|
The oak has historically been the most prized of all the trees. Robuvit, obtained from French oak wood (Quercus robur) through a water extraction process, contains a number of flavonoid compounds: gallic acid, ellagic acid, castalagin, vescalagin and in particular, roburins (A, B, C, D, E) which account for the unique and multi-beneficial properties of this particular wood.
Chronic fatigue is a multi-faceted condition which can affect anyone at any stage of life, regardless of age, sex or socio-economic status. Symptoms range from poor quality sleep to lack of energy, exhaustion, muscle fatigue and various other problems for which there are as yet no treatment standards.
Apart from supplementing with vitamins and mineral combinations, particularly magnesium and some amino acids, medicinal substances are often used to remedy the symptoms of chronic fatigue but they can have side-effects and do not provide a real solution to the problem.
According to data recorded by 89 GPs on 1,428 consultations, prevalence of fatigue is 25%. Fatigue is an important symptom because of its association with physical, psychological and social problems. Prevalence of chronic fatigue syndrome (CFS) is estimated to be 3.28%. It occurs more frequently between the ages of 40 and 59 and is four times more common in women than in men. Symptoms include:
Secondary symptoms include hypersensitivity to noise, abdominal pain, gastro-intestinal discomfort, weight loss, dizziness and mood swings. Robuvit, an oak wood extract standardised in roburins, offers genuine hope for the millions of people suffering from CFS. Possible mechanisms of action include functional changes in ribosomes, the small molecular entities located within cells which produce new proteins in the body.
Changes in ribosomal function have been observed in individuals infected with the Epstein-Barr virus, which is strongly associated with CFS. Support for ribosomal biogenesis and function may thus prove to be a completely new approach to managing CFS. Even for those without CFS, Robuvit can be considered a new-wave supplement for maintaining cellular protein synthesis.
In a clinical study of 80 CFS sufferers, 38 were given Robuvit for six months, with the remaining 42 serving as controls. Participants were evaluated using the Multidimensional Assessment of Fatigue (MAF) questionnaire developed by the University of Washington. Results clearly showed improvements in fatigue and oxidative stress in those taking Robuvit.
A human study involving 91 subjects, published in the journal Panminerva Medica in March 2014, had previously identified all Robuvit's properties. In this six-month study, 48 subjects were given 200mg of Robuvit a day, with 43 serving as controls.
Specific CFS questionnaires, as well as the Brief Mood Introspection Scale (BMIS), were used to assess mood variations in CFS patients. Participants had to have at least five CFS symptoms to be included in the study. Researchers also measured oxidative stress and found increased levels in 61 of the 91 subjects. Assessment was repeated at 3 and 6 months. The study showed that taking Robuvit produced reductions in primary CFS symptoms of:
Notable decreases in secondary symptoms were also observed, particularly in hypersensitivity (to noise, diet, drugs), dizziness, depression, weight changes, mood swings and allergies. Allergies and hypersensitivity as CFS symptoms were recently investigated in a human study involving 30 female volunteers - 14 in a control group and 16 in a test group – in which the effects of Robuvit supplementation on cutaneous reactions (redness and swelling) were evaluated. The supplemented volunteers were given 300mg of Robuvit a day for three days plus an intracutaneous injection of histamine. At the end of the three days, researchers observed a significant reduction in the histamine-induced swelling and redness in the test group, indicating an anti-histamine effect for Robuvit.
Robuvit also has significant antioxidant activity and acts at a sub-clinical, cellular level, distinguishing it from other products which simply tackle symptoms. Its antioxidant properties were highlighted in a pilot study which evaluated markers of oxidative stress, antioxidant enzyme activity (SOD, catalase, glutathione peroxidase) and total antioxidant capacity in plasma. Scientists found that a daily dose of 300mg for one month significantly reduced serum levels of Advanced Oxidation Protein Products (AOPP) and lipid peroxides, and noticeably increased total antioxidant capacity in plasma. In a 12-week, placebo-controlled study of 61 patients (32 receiving Robuvit and 29 controls), a 200mg daily dose of Robuvit (or 300mg/day for those weighing over 80 kilos) normalised levels of ASAT, ALAT, alkaline phosphatase and gamma GT, and reduced plasma oxidative stress.
A small, eight-week pilot study has just been published which suggests that a 300-600mg daily dose of Robuvit may reduce lymphoedema in legs and improve microcirculation and tissue oxygenation. In brief, supplementing with Robuvit:
Other promising but as yet unpublished research has also highlighted its ability to:
Oral toxicity studies show that taking Robuvit is completely safe and is compatible with all other nutritional supplementation. No side-effects have been observed in clinical studies. The average dose is one 100mg Robuvit vegetarian capsule, once or twice a day. In cases of long-standing chronic fatigue, usually associated with oxidative stress, treatment should be continued for three to six months.
|Daily dose: 2 capsules
Number of doses per pack: 30
|Amount per dose|
|Robuvit® (Extract of Quercus robur standardised to 20% Roburins)||200 mg|
|Other ingredients: Acacia gum, white rice bran.|
Beehive products have been growing in popularity over the last few years. Read on to find out more about the positive effects of honey, royal jelly and propolis.
Often disliked for their distinctive taste, cabbages are nonetheless an excellent choice for the winter months. They boast an exceptional nutritional composition and offer beneficial properties for protecting the body.
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