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Diosmin Plus + Hesperidin
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Diosmin Plus + Hesperidin
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68.00 €(73.28 US$) in stock
Hesperidin Methyl Chalcone
Hesperidin Methyl Chalcon is an extract of Citrus aurantium standardised to 98%.
  • Improves circulation and helps with certain venous disorders.
  • May help with symptoms of venous insufficiency, such as cramps or ‘heavy legs'.
  • Contains antioxidant potency, which may combat free radical damage and the effects of oxidative stress.
Diosmin Plus
Diosmin Plus has enhanced bioavailability for treating venous insufficiency and circulation problems.
  • Helps restore vein function and optimal circulation.
  • Helps reduce symptoms of venous insufficiency and haemorrhoids.
  • Helps reduce fragility and permeability of capillaries.
  • Offers more than 4 times greater bioavailability than standard diosmin thanks to state-of-the-art technology.
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Woman with healthy legs

Diosmin Plus is a flavonoid supplement standardised to 80% diosmin, a natural compound with powerful venotonic benefits. It is designed to naturally reduce symptoms of venous insufficiency and improve circulation throughout the body, now available to buy at Supersmart.

Its enhanced bioavailability (the diosmin is 4-10 times better absorbed than standard supplements) makes it, along with the famous VeinoMax, one of the best natural venotonics available.

Who is Diosmin Plus aimed at?

Diosmin Plus is for all those affected by any of the following:

  • Venous insufficiency and circulation problems. This condition is characterised by a defect in the nervous system, specifically in the veins’ valves which enable blood to be transported back up the legs. The consequent pooling of blood produces unpleasant symptoms such as pain and a feeling of heavy, swollen legs. It subsequently leads to the formation of varicosities, varicose veins and sometimes even varicose ulcers and eczema. A number of clinical trials have confirmed the efficacy of bioflavonoids, particularly diosmin, for reducing symptoms of venous insufficiency and improving the circulation (1).
  • ‘Economy class’ syndrome. Those who spend too long confined in a sitting position often develop abnormal swelling in the legs and microangiopathy. This can be prevented or reduced by taking a diosmin supplement.
  • Haemorrhoids. Several clinical trials have shown that diosmin can reduce the pain and bleeding of haemorrhoids (2).

What makes Diosmin Plus such an exceptional venotonic?

Once ingested, it is rapidly converted into diosmetin by enzymes in the gut microflora. The diosmetin is then absorbed across the intestinal wall to be converted in the bloodstream into its more active metabolite: 3, 7-O-diglucuronide (5-6).

Unfortunately, most flavonoids – and diosmin is no exception – are not very soluble, which significantly reduces their absorption through the gastrointestinal wall (7).

To rectify this problem, Supersmart has employed three innovative, high-tech processes:

  1. Micronisation, ie, reducing the particle size of the active principle. This increases its rate of dissolution and that of the contact surface with the intestinal epithelium.
  2. The use of a buffer system which increases the conversion of diosmin into diosmetin in the gastrointestinal cavity.
  3. Granulation, a clustering process which promotes its circulation in blood vessels.

This approach produces a diosmin supplement which is much more absorbable than standard micronised supplements. Two studies have demonstrated that Diosmin Plus is 4-10 times more bioavailable compared with conventional micronised diosmin supplements (8-9).

Buy Diosmin Plus to support venous health.

CompositionDiosmin Plus
Daily dose: 3 capsules
Number of doses per pack: 30
Amount per dose
µSMIN® Plus (Flavonoid complex standardised to 90% total flavonoids and 80% diosmin) 900 mg
Acacia gum.
µSMIN® Plus, GIELLEPI S.P.A., Italy.
Directions for useDiosmin Plus
Adults. Take 3 capsules a day. Each capsule contains 300 mg of µSMIN® Plus.
Blue molecule structure with water droplets

Hesperidin methyl chalcone (HMC) supplement is an extract of Citrus aurantium standardised to 98% hesperidin methyl chalcone delivered in vegetarian capsules, to support venous health and improve circulation, now available to buy at Supersmart.

What is Hesperidin Methyl Chalcone?

Hesperidin methyl chalcone (HMC) is a methylated derivative of the flavonoid compound hesperidin. It is found in several fruits, particularly citrus fruits, the majority of which are grown in Spain. The compound takes the form of a pale yellow, slightly bitter, water-soluble powder.

It is widely used in Japan, as well as in Europe both as a nutritional supplement and an ingredient in cosmetics. It is also available in pharmacies, mainly in combination with other plants such as butcher's broom, for treating circulation problems.

What are the benefits associated with Hesperidin Methyl Chalcone?

Unlike hesperidin itself, HMC is easily solubilised, facilitating its absorption in the gastrointestinal tract. Like all flavonoids, HMC is a powerful antioxidant, and is thus excellent for optimising eye health and protecting the cardiovascular system from oxidative attack. Its main activity, widely supported by clinical studies, lies in maintaining blood vessel integrity and strengthening the capillary network:

  • With a long history of popular use in Asia, hesperidin methyl chalcone has now made a ‘grand entrance' in Europe. Drawing on the many studies conducted on the compound, hesperidin has been formulated into venotropic drugs and nutritional supplements aimed at improving the circulation and combatting certain venous disorders.
  • In a short space of time, hesperidin has come to be seen as an effective treatment for symptoms of venous insufficiency, such as cramps or ‘heavy legs'.
  • It is used in certain drugs as an effective solution to haemorrhoids, particularly in reducing the incidence of attacks.
  • In addition to its pharmaceutical use, hesperidin has also proved of interest to the cosmetics industry. This is primarily because of its antioxidant potency which may combat free radical damage, prevent the effects of oxidative stress, and thus delay cellular ageing.
  • As it helps improve the circulation, hesperidin has also been suggested as a skincare ingredient, aimed at easing the sensation of heavy, tired legs and making them feel lighter and more toned.

These latter developments suggest that HMC may also play a key role in approaches to age-related disorders – in preventing or even treating them. But it is really the compound's overall effects, particularly those related to general circulatory problems, which make such a strong case for supplementing with this very safe product - ideally at a dose of 500-1000mg/day for 2-3 months.

Buy Hesperidin Methyl Chalcone capsules for benefits to circulation and venous support.

CompositionHesperidin Methyl Chalcone
Daily dose: 2 capsules
Number of doses per pack: 30

Amount
per dose

Extract of Citrus aurantium standardised to 98% hesperidin methyl chalcone 1 000 mg
Other ingredients :Acacia gum.
Directions for useHesperidin Methyl Chalcone
Adults. Take two capsules a day, one in the morning and one in the evening.
Each capsule contains 500mg of extract of Citrus aurantium standardised to 98% hesperidin methyl chalcone.

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Diosmin Plus + Hesperidin
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