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Diosmin Plus is a flavonoid supplement standardised to 80% diosmin, a natural compound with powerful venotonic benefits. It is designed to naturally reduce symptoms of venous insufficiency and improve circulation throughout the body, now available to buy at Supersmart.
Its enhanced bioavailability (the diosmin is 4-10 times better absorbed than standard supplements) makes it, along with the famous VeinoMax, one of the best natural venotonics available.
Who is Diosmin Plus aimed at?
Diosmin Plus is for all those affected by any of the following:
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Venous insufficiency and circulation problems. This condition is characterised by a defect in the nervous system, specifically in the veins’ valves which enable blood to be transported back up the legs. The consequent pooling of blood produces unpleasant symptoms such as pain and a feeling of heavy, swollen legs. It subsequently leads to the formation of varicosities, varicose veins and sometimes even varicose ulcers and eczema. A number of clinical trials have confirmed the efficacy of bioflavonoids, particularly diosmin, for reducing symptoms of venous insufficiency and improving the circulation (1).
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‘Economy class’ syndrome. Those who spend too long confined in a sitting position often develop abnormal swelling in the legs and microangiopathy. This can be prevented or reduced by taking a diosmin supplement.
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Haemorrhoids. Several clinical trials have shown that diosmin can reduce the pain and bleeding of haemorrhoids (2).
What makes Diosmin Plus such an exceptional venotonic?
Once ingested, it is rapidly converted into diosmetin by enzymes in the gut microflora. The diosmetin is then absorbed across the intestinal wall to be converted in the bloodstream into its more active metabolite: 3, 7-O-diglucuronide (5-6).
Unfortunately, most flavonoids – and diosmin is no exception – are not very soluble, which significantly reduces their absorption through the gastrointestinal wall (7).
To rectify this problem, Supersmart has employed three innovative, high-tech processes:
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Micronisation, ie, reducing the particle size of the active principle. This increases its rate of dissolution and that of the contact surface with the intestinal epithelium.
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The use of a buffer system which increases the conversion of diosmin into diosmetin in the gastrointestinal cavity.
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Granulation, a clustering process which promotes its circulation in blood vessels.
This approach produces a diosmin supplement which is much more absorbable than standard micronised supplements. Two studies have demonstrated that Diosmin Plus is 4-10 times more bioavailable compared with conventional micronised diosmin supplements (8-9).
Buy Diosmin Plus to support venous health.
CompositionDiosmin Plus
Daily dose: 3 capsules
Number of doses per pack: 30 |
Amount per dose |
µSMIN® Plus (Flavonoid complex standardised to 90% total flavonoids and 80% diosmin) |
900 mg |
Acacia gum.
µSMIN® Plus, GIELLEPI S.P.A., Italy.
|
Directions for useDiosmin Plus
Adults. Take 3 capsules a day. Each capsule contains 300 mg of µSMIN® Plus.
VeinoMax is the gold-standard dietary supplement for supporting the circulation. Its natural venotonic extracts (hawthorn berries, bilberries, horse chestnut, grape seeds …) and exceptional phytonutrients targeted at vein health provide consistent support for the most common circulation problems, such as varicose veins and venous insufficiency.
What is in VeinoMax?
VeinoMax offers an unprecedented synergy of active principles from plant extracts aimed at combatting leg discomfort :
- troxerutin and quercetin, both of which are obtained from the Japanese pagoda tree (Sophora japonica). One of the 50 fundamental plants of Chinese medicine, this ornamental tree bears flower buds which can “eliminate heat from the blood”, according to the Chinese Pharmacopoeia. Given their specific affinity with the outer vein wall and vascular endothelium, its two precious flavonols are among the most widely-studied substances in phlebology (1-2) ;
- hesperidin and diosmin, two flavonoids extracted from bitter orange (Citrus aurantium). Several studies have investigated how these vasoprotective compounds interact with capillary permeability, the underlying inflammatory component and stimulation of blood flow (3-4) ;
- extract of horse chestnut (Aesculus hippocastanum), a natural phlebotonic which helps support vein health and circulation via the specific action of aescin on venous tone and capillary strength. Many scientific articles have noted a subjective improvement in perceived discomfort associated with chronic venous insufficiency (pain, heaviness, swelling …) (5) ;
- extract of blueberry. Rich in anthocyanidins, this dark berry with antioxidant properties helps maintain healthy veins and capillaries by, in particular, acting on the vasomotion of small calibre vessels (6) ;
- extract of grape seed. Through its proanthocyanidin content, it supports vein health by improving the fragility of vascular walls (7) ;
- extract of hawthorn berry, which helps maintain good cardiovascular health. This cardiotonic plant supports the heart’s contractile function and dilation of coronary blood vessels, thereby improving blood supply to the heart muscle (8). It thus exerts a particularly beneficial complementary action in cases of poor venous return;
- vitamin C, which supports normal collagen production and blood vessel function (9).
What are the symptoms of venous insufficiency?
Venous insufficiency is the result of poor venous return. In other words, the blood circulating in the veins of the lower limbs struggles to travel back up to the heart and instead pools in the legs, a problem known as ‘stasis’.
This common complaint, thought to affect 15%-20% of the adult population, is usually caused by both a lack of tone in the vein wall and valve dysfunction in which the small valves meant to ensure blood flows upwards against gravity, do not work properly (10).
It produces various symptoms:
- a feeling of heavy legs, more pronounced at the end of the day;
- restlessness or tingling in the legs;
- muscle cramps in the night;
- swelling of the legs (oedema), especially the calves, ankles or feet;
- formation of varicose veins or spider veins ;
- formation of varicose ulcers (in the case of advanced chronic venous insufficiency).
CompositionVeinoMax
Daily dose : 6 capsules
Number of daily doses per box: 30
|
Quantity per dose |
% of recommended daily amount |
Troxerutin (from 750 mg Sophorae japonica extract standardized to 95 % troxerutin) |
712,5 mg |
* |
Diosmin (from 750 mg of Citrus aurantium extract standardised 90 % diosmin |
675 mg |
* |
Aescin (from 240 mg of horse chestnut extract standardised 18 to 22 % aescin) |
43,2 mg |
* |
Quercetin (from 150 mg of Sophora japonica extract standardised 95 % quercetin) |
142,5 mg |
* |
Vit. C (calcium ascorbate)) |
150 mg |
187% |
Hesperidin (from 67.50 mg of Citrus aurantium extract standardised 95 % hesperidin) |
64 mg |
* |
Anthocyanidins (from 60 mg of blueberry extract standardised 25 % anthocyanidins) |
15 mg |
* |
Proanthocyanidins (from 60 mg of grapeseed extract
standardised 90-95 % proanthocyanidins) |
54 mg |
* |
Vitexin (from 45 mg of hawthorn berry extract standardised 2 % vitexin) |
0,9 mg |
* |
Other ingredients : Acacia gum, rice flour.
* Unspecified |
Directions for useVeinoMax
Adults : take two vegetarian capsules three times a day with each main meal, or as advised by your therapist.