The following protocol is usually recommended for a course of PEA:

• 3 capsules a day, one with each main meal, for the first two months.
• 2 capsules a day for the following two months.
• 1 capsule a day thereafter until the end of the supplementation period.

If necessary, however, PEA can be taken on a continuing basis.

It’s advisable, throughout the supplementation period, to try to follow the measures below:

• Regular exercise whenever possible.
• Acupuncture.
• Massage therapy.
• Relaxation techniques such as meditation or visualisation.

Following extraction, CBD is diluted in hemp seed oil.

Ordinarily, hemp seed oil contains very little CBD (0.0025%). CBD is mostly found in the flowers of Cannabis sativa and, to a lesser degree, the leaves, but not in the seeds. CBD Oil 6% therefore contains hemp seed oil to which CBD extracted from hemp flowers has been added.

When cannabis grows, it produces THC-A and CBD-A, not THC or CBD. It is only when the two molecules are heated that they are decarboxylated into their active forms (27). The conversion of CBD-A into CBD can also be achieved more slowly by exposing the molecule to light, to heat (the temperature of gastric fluids is 37°C) or overtime (28). CBD Oil 6% contains CBD and not CBD-A, as well as small amounts of a number of other phytocannabinoids. There is currently no product on the market offering greater CBD oil benefits.

Following ingestion, PEA is rapidly distributed throughout the body. One study even showed that some of the palmitoylethanolamide molecules reach the brain (3), with a relatively diverse distribution (the cerebral cortex, hypothalamus and white matter are the areas in which most PEA is found).

Are there any contraindications associated with taking PEA?

Over the course of twelve clinical studies conducted since 1972, researchers have not found PEA supplementation to produce any particular side-effects (4) - hardly surprising given that palmitoylethanolamide is produced naturally by the body’s cells.

Nor have any drug interactions been identified to date. However, anyone suffering from kidney or liver problems is advised to start with 400mg daily (1 capsule) and gradually increase the dose over subsequent weeks.

These safety indications only apply to supplements made from pharmaceutical grade palmitoylethanolamide such as our product, PEA. Avoid palmitoylethanolamide of unknown origin to prevent any nasty surprises.

The hemp used in this product contains no THC. It therefore has no narcotic effect and has an excellent safety profile in humans.

Once ingested, CBD is quickly distributed around the body. Its lipophilic nature means it rapidly crosses the blood-brain barrier to reach tissues in the brain. It does not alter the heart rate and affects neither blood pressure nor body temperature. The half-life of CBD is 9 hours, after which it is eliminated vie urine in a metabolised form.

Its softgel format and the fact that SuperSmart guarantees the purity of its ingredients means there are no particular contraindications associated with its use. To date, there have been no public health problems reported with the use of a THC-free hemp oil standardised in CBD.