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Derma Relief + Super Omega3
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Derma Relief + Super Omega3
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Super Omega 3
Super Omega 3 is a 100% natural concentrate of omega-3 (EPA and DHA).
  • Certified Friend of the Sea® (obtained from sustainable fisheries).
  • Supports optimal health of the cardiovascular system.
  • Helps reduce blood triglyceride levels and blood pressure.
  • Contributes to healthy heart and brain function (cognition).
  • The purest and most stable omega-3 supplement on the market.
  • TOTOX (oxidation rate) among the lowest existing: generally 2, always less than 10 for a maximum limit set at 25 by the GOED (Global Organization for EPA and DHA).
Derma Relief
Derma Relief is a natural probiotic formula to help relieve and improve skin problems.
  • Contains four probiotic strains selected for their benefits for the skin, immune system and ability to fight inflammation.
  • Contains vitamin B2, to optimise the health of the skin and mucous membranes.
  • Contains vitamin C, which helps with collagen formation and optimises skin function.
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Middle-aged woman with smiling at camera on the beach

Derma Relief is a probiotic formula to help relieve skin problems, by creating a healthy environment for your gut flora and, therefore, reducing inflammation in the layers of your skin.

Who is Derma Relief for?

Derma Relief is aimed at anyone looking for a natural way to relieve and improve their skin problems and at those for whom standard treatments have not worked.

Stubborn skin problems can include:

  • Acne.
  • Atopic dermatitis.
  • Eczema.
  • Impetigo.
  • Vitiligo.
  • Red patches.
  • Blackheads.
  • Pimples or microcysts.
  • Hyperseborrhea (oily skin).
  • Rashes.
  • Scaly patches.
  • Itching.

What is Derma Relief?

Derma Relief’s formulation is based on a theory widely-documented in the scientific literature (1): that by taking probiotics, you create a healthy environment for your gut flora and reduce inflammation in the layers of your skin.

DermaRelief contains four strains of probiotic with a dual protective coating enabling them to reach the gut in perfect condition. Designed to colonise the gut, these bacterial strains have been carefully selected for their benefits for the skin, immune system and ability to fight inflammation:

  • Lactobacillus casei.
  • Lactobacillus rhamnosus.
  • Lactobacillus plantarum.
  • Bifidobacterium lactis.

DermaRelief also contains several compounds that support the growth of these probiotics or that act in synergy with them:

  • Fructo-oligosaccharides and other oligosaccharides. The role of these carbohydrates, which are naturally present in grains, fruit and the roots of certain vegetables, is to ‘nourish’ the probiotics and help them multiply: they are called prebiotics.
  • Vitamin C. Vitamin C optimises immune function and helps maximise collagen formation in the skin.
  • Vitamin E (in the form of dl-alpha-tocopheryl acetate). When tocopheryls enter the body they are converted into tocopherols and become active: they play a major role in protecting skin cells from oxidative stress. Vitamin E also has anti-inflammatory and vasodilatory properties unrelated to its antioxidant activity.
  • Vitamin B2 (riboflavin). It helps maintain the health of the skin’s mucous membranes (2).

What are the mechanisms of action responsible for DermaRelief’s effects on the skin?

Contrary to what you might think, probiotics are not just for preventing or improving gastrointestinal problems. We now know they confer systemic effects and that these effects can benefit the skin if the probiotic strains are selected carefully.

Fabio Meneghin and his research team analysed 37 clinical trials investigating the dermatological potential of oral probiotics: 13 out of 17 were shown to be effective in terms of prevention, while 15 out of 20 displayed therapeutic efficacy (3).

There are at least three mechanisms responsible for the benefits conferred by the probiotics in DermaRelief.

1) Preservation of the intestinal barrier integrity

Probiotics help strengthen the intestinal barrier’s impermeability, primarily by increasing secretion of immunoglobulin A (IgA) antibodies, the role of which is to neutralise harmful bacteria and toxins in the intestinal lumen. (4).

Strengthening the intestinal barrier prevents various compounds that exacerbate skin inflammation from passing into the bloodstream.

2) Modulation of the skin’s immune system

Probiotics and their derivatives modulate the immune system by activating dendritic cells (5-6), stimulating NK cells (7-8) and inducing T-lymphocyte differentiation.

Dendritic cells and T lymphocytes are indeed instrumental in the improvements observed in the skin following probiotic treatment. Their effects on the immune system produce anti-inflammatory benefits via an increase in production of interleukin 10 (IL10) (9-10), a powerful anti-inflammatory cytokine secreted by the body in response to a number of pathological conditions such as eczema and dermatitis.

3) Modulation of the gut-brain-skin axis

This mechanism relates to the capacity of emotional states (such as depression and anxiety) to alter gut microbiota, increase intestinal permeability and promote systemic inflammation.

Lactic probiotics may be able to moderate the release of a neuropeptide (a polypeptide functioning as a neurotransmitter and neuromodulator) called substance P (11). This neuropeptide is released by the nervous system in response to pain, stress, mood problems and anxiety, but it is found abundantly in the skin in atopic dermatitis, eczema and other skin problems (12). By restricting its release, probiotics thus help reduce skin disorders.

CompositionDerma Relief
Daily dose: 1 stick
Number of doses per pack: 30

Amount
per dose

Lactobacillus casei CBT LC5 1.2 billion CFU
Lactobacillus rhamnosus CBT LR5 0.6 billion CFU
Lactobacillus plantarum CBT LP3 0.6 billion CFU
Bifidobacterium lactis CBT BL3 0.6 billion CFU
Dextrose 700 mg
Polydextrose 630 mg
Fructooligosaccharides 450 mg
Galacto-oligosaccharides 100 mg
Riboflavin 0.45 mg
Vitamin C 25 mg
DL-alpha-tocopheryl acetate 8 mg
Thiamine chloride 0.45 mg
Pyridoxamine 0.45 mg
Other ingredients: cornflour.
Directions for useDerma Relief
Take one stick a day, diluting the contents in a glass of water.
Keep refrigerated.
Fish bank swimming in the sea

Super Omega 3 has been formulated to offer an optimal intake of marine-source omega-3 fatty acids. These natural lipids have scientifically proven effects on the composition of cell membranes as well as on numerous biochemical and physiological processes: regulation of blood pressure, anti-inflammatory responses, platelet aggregation, secretion of mood-influencing neurotransmitters, neuron activity…

Who is Super Omega 3 aimed at?

Super Omega 3 is for all sections of the population.

The World Health Organization, along with all Western countries, recommends a minimum intake of 500mg a day of EPA+DHA in order to maintain health (1), and in particular, to support brain development and function.

Yet numerous studies have shown that this level of intake is a long way from that currently achieved by American and European populations (2-8 times lower than daily recommended amounts).

And while these recommendations apply to healthy individuals, all the indications are that certain categories of people need more of these fatty acids (up to 1000mg/day (2)):

  • Those over 50 (to protect against cognitive decline).
  • Those suffering from chronic inflammation.
  • Those with a large waistline (excess adipose fat).
  • Those with hypertension, hypertriglyceridaemia, hypercholesterolaemia or hyperglycaemia.
  • Those suffering from fatigue or low mood.
  • Those at risk of cardiovascular problems.

What are the recognised benefits of EPA and DHA?

EPA and DHA are molecules that penetrate cell membranes – the layers of fat that demarcate our body’s cells. From this strategic space, they influence a wide variety of the body’s functions.

They affect chronic inflammation and metabolic problems.

When cell membranes take up EPA and DHA, they become more fluid and permeable. This is a really important point as when they’re more rigid, membrane exchange is restricted, promoting chronic inflammation.

In addition, in cases of systemic inflammation, the body can ‘dip into’ this store of omega-3 fatty acids and convert them into anti-inflammatory molecules. With omega-6, the complete reverse happens – they are converted into pro-inflammatory compounds which encourages the development of metabolic dysfunctions such as insulin-resistance and metabolic syndrome.

They reduce the risk of cardiovascular problems

In recent years, 12 studies have demonstrated the benefits of supplementing with omega-3 for preventing acute coronary syndrome and other cardiovascular problems (7).

Several mechanisms are responsible for these effects. First and foremost, supplementing with omega-3 helps lower omega-6 concentrations in membranes, and as a result, reduces their conversion into pro-inflammatory derivatives (8). It also acts on the atheromatous plaque that causes cardiovascular problems: omega-3 help lower blood pressure and reduce triglycideraemia (9) - high levels of triglycerides being a recognised risk factor for heart problems - by lowering the liver’s production of these fats and by increasing their elimination via LDL-transporters. They also stabilise atheromatous plaque by reducing production of inflammatory cytokines and by preventing monocytes from adhering to the vascular wall (10-11). Last but not least, omega-3 regulate a large number of genes, particularly those involved in fat metabolism.

They optimise cognitive function

Several studies, including a prominent one published in 2002, show that supplementing with EPA for several weeks produces a significant decrease in depressive disorders in a high proportion of people suffering from major depression (12-13).

In the same vein, post-partum depression may actually be linked to a reduction in cellular levels of EPA and DHA in pregnant women, resulting in significantly reduced reserves by the end of their pregnancy (14). Scientists have discovered that it takes around a year for initial reserves to be restored to the levels required for healthy functioning of the serotonergic and cholinergic systems (DHA normally represents 10-20% of the fatty acid composition of the brain (15)). Low DHA levels in brain cell membranes do not only result in depression. They also lead to a lack of dopamine in the brain’s cortical regions, which may play a role in cognitive decline and impair the growth and development of the nervous system.

Once integrated into the membrane, DHA makes it more flexible, improving the speed of transduction and neurotransmission. It also affects neural extension development, synapsis establishment, neural plasticity, maturation of neurons and their migration towards appropriate sites, and thus plays a significant role in motor, sensory and cognitive abilities (16). Carlson and his team thus demonstrated the benefits on learning capacity of a diet rich in omega 3.

They protect visual function

DHA represents more than 30% of all the fatty acids present in the retina (17). It is one of the most important compounds constituting the membranes of the outer segments of photoreceptors (18). The constant renewal of these cell components requires a regular and high intake of DHA or its precursors. DHA also supports a fundamental step in the phototransduction mechanism (19) which allows the conversion of light energy into a nerve signal (20). It is thus no surprise that deficiencies in DHA are associated with a number of visual dysfunctions such as AMD (21-23).

What makes Super Omega 3 so exceptional?


1) It’s a 100% natural supplement with optimal bioavailability

Like all the omega-3 supplements available to buy at Supersmart (Super EPA and Super DHA), Super Omega 3 contains EPA and DHA fatty acids in their natural form (triglycerides). These are more expensive than the synthetic form (ethyl esters), but studies show they may be easier to digest (no ethanol is released) and twice as bioavailable.

In addition, unlike many other laboratories, we have chosen to develop our product from wild fish oil. A number of studies have shown that farmed fish contain less omega-3 and more omega-6 (24). This is because such fish are fed inferior food: whereas wild fish feed on tiny fish, crustaceans and microalgae which are very rich in omega-3, farmed fish are often fed cereals and vegetable oils high in omega-6. What’s more, they are often farmed in inhumane and unsanitary conditions, and are routinely given antibiotics and anti-fungals.

2) The production methods used respect the environment

To ensure it offers optimal quality, Super Omega 3 is produced from a top-quality fish oil, obtained from fishing zones off the coasts of Peru and Chile free from any industrial contamination. Fish are selected for their naturally high content in omega-3 fatty acids (sardines, mackerel and anchovies). These fish oils are thus certified Friend of the Sea® which means they come from sustainable fisheries that meet strict criteria, with guaranteed management of fishing quotas. Smaller fish are prioritised as larger ones have lived longer and have accumulated waste products: mercury, dioxins and even pesticides.

3) It hasan optimal safety profile

In order to guarantee it is completely free from contaminants (PCB, heavy metals, dioxins), SuperSmart uses patented purification technology. This is a natural process called enzymatic hydrolysis which produces the highest concentration of EPA and DHA in a 100 % pure oil.

In addition, as omega-3 fatty acids are highly vulnerable to oxidation, we add natural ingredients to protect them and maximise their shelf life. Indeed, when omega-3 are oxidised, they are converted into trans fatty acids devoid of any health benefits. It’s therefore essential to protect them with antioxidants so that they retain their beneficial effects over time. That’s why SuperSmart has chosen to add tocopherols (vitamin E) to this exceptional formulation. It’s also why it’s best to store them in a cool, dry place, away from sunlight.

CompositionSuper Omega 3
Daily serving: 3 softgels
Number of servings per bottle: 30
Quantity per serving
EPA in the form of fish oil triglycerides 465 mg
DHA in the form of fish oil triglycerides 345 mg
Other ingredients:tocopherols.

Each softgel contains 155 mg of EPA and 115 mg of DHA.
Warning: Product derived from fish.
Directions for useSuper Omega 3
Take three softgels a day at mealtimes.

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Derma Relief + Super Omega3
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(88.75 US$)
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