0
en
US
X
× SuperSmart Shop by health concern Shop by product Bestsellers New products Promotions My account Smart Prescription Blog Loyalty scheme Language: English
Welcome Shop by health concern Brain nutrition Sulbutiamine 200 mg
-35%
Sulbutiamine 200 mg
Sulbutiamine 200 mg Sulbutiamine 200 mg
Sulbutiamine 200 mg
Brain nutrition Customer reviews
20.80 €32.00 €(23.24 US$)
-35%
Today is available
Description
A non-amphetamine psychostimulant with antiasthenic and energising effects
-
+
100 Veg. Caps.
Add to basket Certificate of Analysis
Wish list
Woman drinking coffee and on the computer

Sulbutiamine 200 mg Capsules

Sulbutiamine is a synthetic derivative of thiamine (vitamin B1). As a dimer combining two modified thiamine molecules, it readily crosses the blood–brain barrier thus increasing levels of thiamine and thiamine phosphate esters in the brain. Sulbutiamine was developed in Japan by Taisho Pharmaceutical in 1965.

What are the benefits associated with Sulbutiamine?

Sulbutiamine is a psychostimulant, the anti-asthenic and energising effects of which are the result of modification of the thiamine ring, formation of a disulphide bridge, creation of a lipophilic ester and opening of the thiazole cycle. The resulting new lipophilic compound is therefore responsible for its valuable properties.

Sulbutiamine's main benefit lies in its ability to combat asthenia by selectively targeting the areas involved in the condition. Asthenia is essentially a form of chronic fatigue that is cerebral rather than neuromuscular in origin. In trials conducted on this compound, in which sulbutiamine was given for 15 days to patients suffering from craniocerebral trauma or post-infectious chronic fatigue, 916 of the 1772 patients involved in the trial experienced complete recovery.

What do studies say about Sulbutiamine?

Following this positive result, scientists expanded their research to focus on other potential areas of activity:

  • Sulbutiamine acts as a caffeine-like energising agent, but without the latter's stimulant effect. It can be compared to nootropic derivatives that increase mental energy, stamina and brain activity while facilitating the conversion of carbohydrates into energy directly usable by brain cells. This use of energy is specific to the brain, unlike other organs which are able to selectively use proteins or fats. The fact that it increases energy in the brain helps improve cognitive processes in general.
  • Memory recall and ability to reason occur more rapidly. The mind becomes clearer, and in some people, it also contributes to improved visual and auditory perception. Taking sulbutiamine results in stimulation and upregulation of the reticular system, the brain's attention and motivation centre, but with the added benefit that it does not lead to stress, nervous tension or hyperactivity. Sulbutiamine improves memory by maximising cholinergic and dopaminergic activity in the hippocampus as well as glutamatergic transmission in the prefrontal cortex.
  • As a result of these mechanisms, mice have been observed to perform better in operant conditioning and object recognition tests. Recent research showed sulbutiamine resulted in a significant improvement in daily activity in people with early-stage Alzheimer's disease, especially when it was combined with an acetylcholinesterase-inhibitor. A randomised, double-blind study using donepezil hydrochloride as the anticholinesterase agent produced better results in patients than donepezil and a placebo.

  • Sulbutiamine has a positive effect on behavioural inhibition ranging from fearfulness and timidity to symptoms associated with depression (even though it is not an anti-depressant as such). In a double-blind, placebo-controlled study, a 600mg daily dose of sulbutiamine administered for two months, produced a greater improvement in psycho-behavioural inhibition after just four weeks treatment compared with placebo. These improvements were apparent in emotional, cognitive and behavioural inhibition.
  • The study's authors concluded that sulbutiamine “facilitates the rehabilitation of patients in their social, professional and family lives”. It can also be taken alongside conventional anti-depressants.
  • When administered at a dose of 600mg/day for 30 days, sulbutiamine was seen to improve erectile dysfunction in 16 out of 20 study participants. This was undoubtedly the result of its disinhibitory effect linked to fear of failure, but these positive results could perhaps lead to the prescription of lower doses of substances designed to address this problem - an important benefit given that such substances may have side-effects, particularly for cardiovascular health. Sulbutiamine has negligible side-effects, the only exceptions being a rare allergic skin reaction or mild irritation in older people.
Composition
Daily dose: 2 capsules
Number of doses per pack: 50
Amount per dose
Sulbutiamine 400 mg
Other ingredients: Acacia gum, rice flour.
Directions for use
Adults. Take 2 capsules a day.
Each capsule contains 200 mg of sulbutiamine.

Featured products

New
Daily 3®Daily 3®

The most complete multivitamin supplement you can take in a single capsule

49.00 €(54.75 US$)
+
Lactobacillus gasseriLactobacillus gasseri

A probiotic strain that’s particularly effective for weight control In gastroresistant DR Caps™ for optimum efficacy.

21.00 €(23.47 US$)
+
New
CBD 25 mgCBD 25 mg

Natural, powerful analgesic for long-lasting pain relief

63.00 €(70.40 US$)
+
Melatonin Spray 1 mgMelatonin Spray 1 mg

All the efficacy of prolonged-release melatonin in a convenient, metered-dose, sublingual spray.

18.00 €(20.11 US$)
+
Berberine 500 mgBerberine 500 mg

A natural and powerful new weapon against type II diabetes

32.00 €(35.76 US$)
+
New
Senolytic ComplexSenolytic Complex

Senolytics: a revolutionary formula for destroying the senescent cells responsible for aging

84.00 €(93.86 US$)
+
Vitamin D3 5000 IUVitamin D3 5000 IU

To help prevent the risks of vitamin D deficiency Fat-soluble vitamin in oil form = increased bioavailability

18.00 €(20.11 US$)
+
Super Omega 3 - 500 mgSuper Omega 3 - 500 mg

EPA and DHA: one of the most natural, pure, powerful and stable product on the market

25.00 €(27.93 US$)
+
Newsletter
Subscribe to our newsletter
and obtain a 5% permanent discount
Our selection of articles
How can you preserve your memory?

Are you worried about memory problems and memory loss? Of course you are. But are you using your memory enough and are you taking the proper daily steps to preserve it?

What’s the best supplement for boosting memory?

Are there any dietary supplements that genuinely help improve memory and cognitive problems?

Magnesium: the best forms for relieving pain, preventing hypertension and improving memory

There are so many different forms of magnesium … Which should you choose for optimal absorption?

Sulbutiamine 200 mg
-
+
32.00 €20.80 €*
(23.24 US$)
Add to basket
© 1997-2019 Supersmart.com® - All rights reserved
© 1997-2019 Supersmart.com®
All rights reserved
Nortonx
secure
Advent calandar ×