1 free mask per order, 1 free ‘mask+hydroalcoholic gel’ pack per order worth €120 or more
× SuperSmart Learn by health topic New articles Popular articles Visit our shop My account Smart Prescription Blog Loyalty scheme Language: English
Slimming and weight control Features

What is lipolysis?

Lipolysis is the body’s mechanism for breaking down fats to make them absorbable and usable. There are two types: gastrointestinal lipolysis, which takes place during digestion, and adipocyte lipolysis, concerned with stored fat, which is often referred to as ‘fat-burning’. How can you use it to help achieve your slimming goals?

Woman taking exercise to lose weight and slim down
Exercise triggers lipolysis which burns fat and helps you slim down.
Rédaction Supersmart.
2020-03-02Comments (0)

Digestive lipolysis, or breakdown of dietary fats

This form of lipolysis breaks down dietary fats, i.e., those we ingest when we eat food. The vast majority of these are triglycerides, complex lipids that are too large to be absorbed intact by the gut. They need to be made digestible when they pass into the intestine: from here, they are released into the bloodstream.

The digestion of dietary fats is initiated in the stomach by gastric lipase. Lipases are ‘fat-splitting’ enzymes. In the stomach, they emulsify triglycerides to produce smaller lipids (primarily monoglycerides and diglycerides).

The production of monoglycerides then triggers the synthesis of pancreatic lipase. This acts in the small intestine, breaking down 75% of the triglycerides ingested. It is also in the small intestine that biliary acids (contained in bile) come into play. Secreted by the liver and stored in biliary vesicles, these acids facilitate the digestion of large lipids by emulsifying them into small droplets. Once digested via this joint lipase/bile salt action, lipids are absorbed through the intestinal mucosa. Any excess dietary fats are stored in the form of triglycerides in adipocytes. This process is called strong>lipogenesis.

Under exercise conditions, adipocyte lipolysis eliminates fats stored in adipose tissue

Adipocytes are specialised fat-storing cells: they constitute the body’s principal store of available energy. Adipocyte clusters form adipose tissue which is found in different proportions and at different sites in the body depending on the individual. Men primarily have adipose tissue around the abdomen, while in most women, it is found on the thighs, buttocks, stomach and breasts. Excess fat produces a form of cellulite, responsible for the infamous ‘orange peel skin’.

Adipocyte lipolysis occurs when the body needs energy (during exercise or fasting...) and is unable to obtain it directly from the diet.

When this is the case, the body emits various hormone signals (adrenaline, noradrenaline, cortisol, ghrelin...), triggering a metabolic cascade that culminates in the mobilisation of... those same lipases! They break down the triglycerides present in adipocytes, releasing glycerol, fatty acids and... energy. The glycerol is predominantly eliminated by the kidneys. As for the fatty acids, they can either be broken down in the mitochondria of cells for energy production (beta-oxidation), or when present at excess levels, they can also be used to produce ketone bodies in the liver. These are a source of energy for the brain when there is insufficient glucose available. Prolonged fasting increases the production of ketone bodies, and in excess, they are toxic. It’s wise, therefore, to fast only under supervision.

How can you boost lipolysis to burn fat and aid weight loss?

To burn fat stored in adipose tissue in order to lose weight and slim down, you need to expend more energy. There are several natural and effective ways of doing this.

So you now have a complete range of options for burning excess fat and achieving a trimmer figure!


  1. Carrière, Frédéric. (2013). La lipolyse gastro-intestinale chez l’homme. Lipid Nutri +.
  2. D. Langin. Mobilisation des triglycérides du tissu adipeux. Act. Méd. Int. - Métabolismes - Hormones - Nutrition, Volume VI, n° 2, mars-avril 2002.
  3. Activité physique et lipolyse adrénergique - Publications Inserm.
  4. Fernanda Reis de Azevedo, Dimas Ikeoka, Bruno Caramelli, Effects of intermittent fasting on metabolism in men, Revista da Associação Médica Brasileira, Volume 59, Issue 2, 2013, Pages 167-173.


You must be connected to your account to leave a comment
Be the first to review this article
Our selection of articles
Ketogenic diet with meat, fish, eggs, avocados and the word keto
Why start a ketogenic, or keto, diet?

The keto diet, high in fat, produces rapid weight loss. Here’s a quick rundown of what you need to know before launching into a diet of this kind.

Brown adipose tissue
What is thermogenesis? What can you do to boost it?

You may have heard that thermogenesis helps you lose weight, but what exactly is it? How does it work and how can you stimulate it to enhance a diet plan? Supersmart has the answers.

Achieving a flat stomach: four natural slimming supplements that can help

Say goodbye to all those low-calorie diets with their risks and yo-yo effects. Much better solutions are available for achieving long-lasting slimming success.

Weight loss: 7 key facts on satiety

What is the sensation of satiety? How can it help us lose weight? And how do we recognise it? To answer these questions and more, we’ve compiled a summary of 7 key facts on satiety:

6 top tips to put an end to snacking

We all know it – snacking is one of the main obstacles to staying in shape or losing weight. But it’s not always easy to say no in the face of an intense craving or a dip in energy...

Lose weight before summer: your essential slimming checklist!

Want to lose weight before summer but don’t know where to begin? Don’t be tempted by draconian diets promising miraculous results! Instead, follow our effective slimming tips. They will genuinely help you regain your figure, without the frustration or dreaded yo-yo effect. Discover our winning slimming checklist and turn your pre-summer weight loss goals into reality!

Products which must be of interest

Lactobacillus gasseriLactobacillus gasseri

A probiotic strain that’s particularly effective for weight control In gastroresistant DR Caps™ for optimum efficacy.

21.00 €(24.82 US$)
Advanced Fat BurnerAdvanced Fat Burner

Lose those extra inches with the help of the latest scientific advances

69.00 €(81.54 US$)
CSAT® 250 mgCSAT® 250 mg

Carob extract for controlling the desire to snack

19.00 €(22.45 US$)

Advanced thermogenic formulation, improved and strengthened

56.00 €(66.18 US$)
Garcinia cambogiaGarcinia cambogia

A fruit rind which helps restrict fat storage

24.00 €(28.36 US$)
Viscerox™ 100 mgViscerox™ 100 mg

Helps reduce abdominal fat

47.00 €(55.54 US$)
Weight Loss BoosterWeight Loss Booster

Speeds up weight loss via complementary mechanisms

27.00 €(31.91 US$)
Fat & Carb Blocker 200 mgFat & Carb Blocker 200 mg

The latest-generation, 100% natural slimming supplement - for effective reduction of calorie intake

24.00 €(28.36 US$)
© 1997-2020 Supersmart.com® - All rights reserved
© 1997-2020 Supersmart.com®
All rights reserved