- Immune-stimulant and anti-tumour properties.
- Stimulates the activity of various groups of white cells including NK (natural killer) cells.
- Used for many years in traditional Asian medicine.
This dietary supplement has been formulated to offer the benefits of AHCC (Active Hexose Correlated Compound), a rare compound developed by Japanese scientists. It is obtained by fermenting an extract of a mushroom popular in Asia and Europe called shiitake (Lentinus edodes). Interest in the health benefits of this mushroom is far from recent however – it has been used for many years in traditional Asian medicine. The result of considerable research, AHCC offers the benefits of a combination of different active principles with immune-stimulant and anti-tumour properties.
Since it was developed and its therapeutic virtues revealed, AHCC has been used by many thousands of people, its use supported by studies conducted in over 30 university research institutes and 700 hospitals in Japan and across the world.
In order to offer a high-quality immune-stimulant supplement, shiitake extracts standardised to 60% AHCC are obtained in a laboratory in accordance with GMP and ISO 9100 & 22000 standards, and delivered in capsules containing an optimal 500mg, with a suggested dose of one to two capsules a day. This dose can be adapted to individual needs and the advice of your therapist. For optimal efficacy, AHCC's beneficial effects can be complemented by other natural active principles such as lactoferrin, a powerful antioxidant with immune-stimulant properties. The formulation Resveratrol Synergy is also a valuable aid with its exceptional antioxidant content, while the patented product AC-11 can help prevent mutations to DNA.
|Daily dose: 2 Caspusles
Number of doses per pack: 30
|Shiitake mushroom (Lentinus edodes) root extract (containing AHCC).||1 000 mg|
|Other ingredients :Acacia gum.|
Derma Relief is a probiotic formula to help relieve skin problems, by creating a healthy environment for your gut flora and, therefore, reducing inflammation in the layers of your skin.
Derma Relief is aimed at anyone looking for a natural way to relieve and improve their skin problems and at those for whom standard treatments have not worked.
Stubborn skin problems can include:
Derma Relief’s formulation is based on a theory widely-documented in the scientific literature (1): that by taking probiotics, you create a healthy environment for your gut flora and reduce inflammation in the layers of your skin.
DermaRelief contains four strains of probiotic with a dual protective coating enabling them to reach the gut in perfect condition. Designed to colonise the gut, these bacterial strains have been carefully selected for their benefits for the skin, immune system and ability to fight inflammation:
DermaRelief also contains several compounds that support the growth of these probiotics or that act in synergy with them:
Contrary to what you might think, probiotics are not just for preventing or improving gastrointestinal problems. We now know they confer systemic effects and that these effects can benefit the skin if the probiotic strains are selected carefully.
Fabio Meneghin and his research team analysed 37 clinical trials investigating the dermatological potential of oral probiotics: 13 out of 17 were shown to be effective in terms of prevention, while 15 out of 20 displayed therapeutic efficacy (3).
There are at least three mechanisms responsible for the benefits conferred by the probiotics in DermaRelief.
Probiotics help strengthen the intestinal barrier’s impermeability, primarily by increasing secretion of immunoglobulin A (IgA) antibodies, the role of which is to neutralise harmful bacteria and toxins in the intestinal lumen. (4).
Strengthening the intestinal barrier prevents various compounds that exacerbate skin inflammation from passing into the bloodstream.
Probiotics and their derivatives modulate the immune system by activating dendritic cells (5-6), stimulating NK cells (7-8) and inducing T-lymphocyte differentiation.
Dendritic cells and T lymphocytes are indeed instrumental in the improvements observed in the skin following probiotic treatment. Their effects on the immune system produce anti-inflammatory benefits via an increase in production of interleukin 10 (IL10) (9-10), a powerful anti-inflammatory cytokine secreted by the body in response to a number of pathological conditions such as eczema and dermatitis.
This mechanism relates to the capacity of emotional states (such as depression and anxiety) to alter gut microbiota, increase intestinal permeability and promote systemic inflammation.
Lactic probiotics may be able to moderate the release of a neuropeptide (a polypeptide functioning as a neurotransmitter and neuromodulator) called substance P (11). This neuropeptide is released by the nervous system in response to pain, stress, mood problems and anxiety, but it is found abundantly in the skin in atopic dermatitis, eczema and other skin problems (12). By restricting its release, probiotics thus help reduce skin disorders.
If you’re still wondering whether to try DermaRelief, here are six reasons that should convince you.
Our gut flora enables the production of vitamins which the body is unable to synthesise, as well as the digestion of complex molecules, and even supports the efficacy of the immune system. The symbiotic relationship between the various bacterial strains that make up our gut flora has played a key role in the evolution of the human species.
Nowadays however, a number of factors such as over-consumption of ultra-processed foods and excessive use of anti-microbial agents have unfortunately contributed to a profound change in the diversity and quantity of the beneficial bacteria colonising our intestines, a significant development given that women pass their microbiota onto their babies (20). At the same time, the incidence of skin allergies and chronic dermatological conditions is continuing to rise, especially in Western countries.
Probiotic supplementation helps restore the balance of microbiota when it has been disrupted, for example, by antibiotic treatment (21).
There are a number of additional steps you can take to enhance the effects of DermaRelief:
DermaRelief can be happily combined with other supplements available to buy at Supersmart to boost the immune system such as AHCC or those designed to maintain the structure of skin tissue such as Polypodium leucotomos, an extract of fern popular in South American traditional medicine. In order to achieve the 1:1 ratio of omega 6:omega 3, it may also be helpful to take omega-3 supplements.
The product comes in 2g sachet ‘sticks’ which contain 3 billion lactic bacteria, which should be kept refrigerated. One stick a day is a sufficient dose.
You can either dilute the contents of the stick in a glass of water and drink, or swallow it straight from the sachet.
Buy Derma Relief to improve skin and intestinal health.
|Daily dose: 1 stick
Number of doses per pack: 30
|Lactobacillus casei CBT LC5||1.2 billion CFU|
|Lactobacillus rhamnosus CBT LR5||0.6 billion CFU|
|Lactobacillus plantarum CBT LP3||0.6 billion CFU|
|Bifidobacterium lactis CBT BL3||0.6 billion CFU|
|Vitamin C||25 mg|
|DL-alpha-tocopheryl acetate||8 mg|
|Thiamine chloride||0.45 mg|
|Other ingredients: cornflour.|