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Lion's Mane + Super DHA
Lion's Mane + Super DHA Lion's Mane + Super DHA Lion's Mane + Super DHA
Lion's Mane + Super DHA
Brain nutrition Customer reviews
49.49 €(55.15 US$) is available
Description
Fish oil-based DHA supplement for preventing cardiovascular problems
  • Contains a number of omega-3 fatty acids.
  • Reduces certain risk factors for cardiovascular disease and lowers the risk of recurrent heart attacks.
  • Beneficial for the prevention of coronary disease and the treatment of depression.
Nootropic mushroom with powerful regenerating properties
  • Contributes to neuron growth and survival (neurotrophic effects).
  • Obtained by dual-extraction (water decoction and alcohol) for maximum preservation of the mushroom’s active principles.
  • Guaranteed to contain 30% β-glucan polysaccharides.
  • Guaranteed content in hericenones.
  • 100% natural and safe excipients.
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Lion’s Mane

Hericium erinaceus, also known as Lion’s Mane, is an edible mushroom which has been used for centuries in traditional Chinese medicine. It is rich in exceptional compounds such as β-glucans, polysaccharides associated with lowering blood cholesterol, as well as hericenones which support neuron function.

Hericium erinaceus, the champion of neuroprotection

In China, where it originated, it’s called "hóu tóu gū" and in Japan, "yamabushitake". A highly unusual mushroom that resembles a long white beard or lion’s mane, its use in Chinese medicine dates back to the Han dynasty, 200 years BC, a period when it was already considered to have extraordinary medicinal properties.

In recent years, as interest in traditional remedies has grown, a number of scientific studies have confirmed its traditionally-recognised therapeutic benefits and have highlighted a remarkable physiological property: Lion’s Mane protects, optimises and repairs the nervous system.

Which of Hericium’s compounds account for these benefits?

The Hericium erinaceus mushroom is particularly rich in bioactive substances, most of which are believed to contribute to its medicinal properties. However, it is undoubtedly the β-glucan polysaccharides and hericenones which are of most interest. The former are a form of soluble fibre which positively affect lipid metabolism, while the latter are phenolic compounds that support neuron function.

Neurotrophic and nootropic effects of Lion’s Mane

The most exciting potential offered by H. erinaceus relates to neuron activity. Studies show that extracts of Hericium erinaceus mushrooms are able to increase production of nerve growth factor (NGF)(6), a neuropeptide known for its key role in neuron growth and survival (7-9), particularly in the part of the brain responsible for memory-processing called the hippocampus. This effect is due to the properties of hericenones of which Lion’s Mane has a guaranteed content.

NGF is a protein involved in regulating the growth, proliferation and survival of central and peripheral neurons. It plays a role in numerous mechanisms:

  • the ability of neurons to bind to each other and form synapses;
  • maintaining neuron populations over time;
  • axonal growth (a key stage in neural circuit assembly which is important for final neuron size);
  • optimum efficacy of mitochondria (the ‘powerhouses’ where energy conversion takes place) in neurons (34-35);
  • axonal regeneration or sprouting processes following trauma (recovery of damaged nerve tissue) ;
  • increase in specific activity of enzymes involved in synthesis of catecholamines and of substance P in sensory neurons;
  • improving myelinisation of nerve fibres (30-32).

NGF is peptide produced by a large number of cells such as those of the immune system, but production declines with age and in the presence of certain disease states. Unfortunately, NGF cannot be used in a treatment or preventative capacity as it is unable to cross the blood-brain barrier. We therefore have to rely on natural compounds with a lower molecular weight (which can cross this barrier) that promote NGF synthesis within the body. That’s exactly what the hericenones in Lion’s Mane do.

Several studies have demonstrated the effects of H. erinaceus on mental efficacy in people with cognitive problems (33) and its use in dementia, cognitive dysfunction and memory problems (10). It seems that it acts primarily as a nootropic and that it’s necessary to take a supplement in order to maintain the effect.

Other properties of Lion’s Mane

1) Anti-cancer and immune-modulating effects. A number of studies have shown that H. erinaceus offers benefits against cancer. Its polysaccharides may increase numbers of immune cells such as macrophages and T lymphocytes (1) as well as nitric oxide (NO) production and cytokine expression (2). Other research has shown extracts of H. erinaceus to increase the cytolytic activity of Natural Killer (NK) cells and to potentially inhibit neoangiogenesis in tumours. One study (4) also showed it was able to combat proliferation of pre-cancerous cells and induce their death (apoptosis).

2) Cardioprotective effects. As indicated by traditional Chinese medicine, H. erinaceus offers benefits for cardiovascular health. Its lipid-lowering effect is due to the action of the polymers it produces. When administered orally, these natural compounds are able to reduce blood levels of LDL-cholesterol and triglycerides, and increase those of HDL-cholesterol. It’s thought that polymers may also play a role in modulating the expression of a gene involved in lipid metabolism (5).

3) Antioxidant effects. Oxidative stress plays a key role in many pathologies including cancer, and cardiovascular and neurodegenerative diseases (12). Oxidative stress is the result of an imbalance in pro-oxidative and antioxidant agents but can be inhibited, thus helping to prevent irreparable damage to the body, by consuming plenty of antioxidant-rich foods or by taking supplements. Extract of Hericium erinaceus is one such supplement, as it can neutralise free radicals and prevent cell membrane peroxidation (13), a process involved in ageing. These effects are due to its phenolic compounds (14) and polysaccharides (15).

4) Support for stomach health. Several years ago, a study demonstrated the benefits of Hericium erinaceus in relieving stomach ache (16), an effect believed to be related to its saponin content.

Huge advantage of dual extraction

Liquid solvents such as water are normally used to obtain a mushroom extract. This acts a bit like a vegetable soup where the hot water enables chemical compounds to be extracted from solids. Immersing Hericium erinaceus in hot water for a certain period, allows all its water-soluble compounds, including its precious β-glucans, to be extracted. The liquid obtained is then dehydrated, producing a powder that’s highly-concentrated in active principles.

In the case of most Hericium erinaceus extracts, the production process stops there. But Hericium erinaceus also contains compounds non-water-soluble compounds such as hericenones. In order to recover these, a second extraction by alcohol is also required. This is vital step since it’s the hericenones which are primarily responsible for the mushroom’s benefits for neuron function (they stimulate production of NGF). Lion’s Mane is one of the rare supplements to undergo this dual extraction process and thus offers a guaranteed content in both polysaccharides (water extraction) and hericenones (alcohol extraction).

Are there other measures that can be combined with Hericium erinaceus supplementation to support neuron function?

Numerous studies have shown that neuroplasticity and neurogenesis can be improved by at least four factors:

  • engaging fully in projects, cognitive and social activities(17-19). Learning and mental exercises encourage the survival phase of neurogenesis by stimulating integration of neurons in existing neural circuits. Repeating these activities (or increasing their difficulty or intensity) leads to improved myelinisation of neuronal extensions, enabling faster circulation of information;
  • increasing intake of omega-3 and B vitamins(20-22). Neurons generated in adults are small in size and have very high requirements for essential fatty acids, particularly omega-3 fatty acids, in order to produce their demanding cell membranes. Omega-3 fatty acids are universally recognised by the scientific community and European health authorities as helping to maintain cognitive function, particularly DHA (a natural-source fatty acid, a high quality form of which is found in Super DHA). Adult neurons also have high requirements for vitamins B2, B6 and B12, all of which are essential elements but are increasingly scarce in modern diets;
  • increasing levels of physical activity(23-24). Physical activity increases the proliferation involved in neurogenesis;
  • improving stress management(25-26). Several studies have shown the highly damaging effects of stress – whether physical or psychosocial - on cell proliferation and neurogenesis in general. It’s therefore essential to protect yourself from stress as much as possible, or failing that, to know how to reduce its effects (through exercise,adaptogen plants, breathing techniques, etc.)

Several species of mushrooms such as Cordyceps (27), Pleurotus (28) and Ganoderma (29) are known to offer similar effects to those of Hericium erinaceus. It may therefore be beneficial to combine Lion’s Mane with Reishi Extract to enhance its anti-cancer effects, or even with Huperzine A to maximise the neuroprotective effects of Lion’s Mane.

When and how should Lion's Mane supplement be taken?

Lion’s Mane supplements contain eight times the concentration of active principles as the plant powder. They have a guaranteed content of beta-glucan polysaccharides of 30% (150mg per capsule), and of hericenones, due to the dual extraction technique used.

The recommended dose to take is 1-2 capsules a day, preferably with meals. The risk of side-effects is very low and Lion’s Mane can thus be taken for 1-3 months. Having said that, this mushroom should not be taken by those with disorders where NGF is already elevated such as allergies, fibromyalgia or polycystic ovary syndrome…

Updated: 30/03/2018

Notes

This product should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. It’s important to follow the directions for use, the recommended daily dose and the ‘use-by’ date. It is not recommended for women who are pregnant or breastfeeding, or for children under 15. Keep out of reach of young children. Store in a cool, dry place.

CompositionLion's Mane
Daily dose: 3 capsules
Number of doses per pack: 30

Amount
per dose

Extract of Lion’s Mane (Hericium erinaceus) 8:1 standardised to 30% polysaccharides 1500 mg
Other ingredients: Acacia gum, rice flour.
Directions for useLion's Mane
adults. Take 3 capsules a day.
Each capsule contains 500 mg
Purple Softgels

Our dietary supplement Super DHA has been specifically formulated to provide docosahexaenoic acid, commonly known as DHA. Numerous scientific studies have been published on this substance – indeed, DHA is one of the most established of the omega-3 fatty acids. The body needs omega-3 fatty acids, often referred to as ‘good fats', in order to function properly. They are also considered essential – in other words, they must be ingested from the diet as the body is unable to produce them.

In the case of DHA, this means eating foods rich in omega-3s such as oily fish. However, dietary sources may not provide sufficient levels, hence the development of a number of omega-3-rich supplements. In order to offer the best possible omega-3 supplement, our teams have been working to develop an innovative formulation that combines DHA with another form of omega-3: eicosapentaenoic acid or EPA. Following extensive testing, the result is this new Super DHA supplement, offering a complete omega-3 solution.

What are the benefits associated with Super DHA?

Deciding to supplement with DHA is not an insignificant choice. This omega-3 has been studied since the 1970s for its many benefits to human health. Scientists believe it plays numerous roles within the body. It is particularly involved in several key functions in the brain, nervous system, cardiovascular system and retina. Omega-3 contributes to:

  • The development and activity of the retina, brain and nervous system;
  • Brain development in the fetus, baby and child;
  • Fluidity of cell membranes, thus promoting the ion exchanges and electron transfers needed for several bioenergy reactions;
  • Lipid functions, by improving the lipid profile.

In addition to supporting normal body function, DHA has aroused scientific interest for its health-promoting properties. A number of studies have been conducted on the benefits of omega-3s in preventing and treating certain disorders. Supplementation with DHA and EPA has demonstrated promising results for:

  • Lowering the heart rate and blood pressure, thus identifying these omega-3 fatty acids as beneficial for those suffering from hypertension;
  • Reducing blood triglycerides, excess levels of which are involved in the development of hyperlipidaemia which is associated with an increased risk of cardiovascular disease;
  • Maintaining normal cholesterol levels, so preventing a rise in the bad cholesterol responsible for cardiovascular problems.

As a result of these effects, it seems omega-3 is particularly important for preventing certain forms of cardiovascular disease, including coronary diseases. Other studies have shown that omega-3 supplementation may offer benefits in lowering the risk of recurrent heart attacks, improving depression and reducing symptoms associated with the menopause and psoriasis.

How is Super DHA produced?

In order to offer the best possible omega-3 product, our Super DHA supplement is produced from a high quality fish oil obtained from several different fish species (sardines, mackerel and anchovies) selected for their naturally high content in omega-3 fatty acids. These premium fish also have Friend of the Sea certification, meaning they come from sustainable fisheries that conform to strict criteria with guaranteed management of fishing quotas. Located along the coasts of Peru and Chile, these clean fishing zones are free from industrial contamination.

A molecular distillation process further enhances the quality of our omega-3 supplement. This innovative technique not only removes all traces of contaminants (mercury, lead, arsenic) but also provides an optimal DHA concentration. This produces a fish oil standardised to 50% DHA and 10% EPA. To ensure maximum benefit from these omega-3s, the DHA and EPA are delivered in softgels, with a recommended dose of one to two capsules per meal. This dose can be adapted according to your needs and the advice of your therapist. You can buy this complete DHA formulation today, with our easy, on-line ordering system and extensive worldwide delivery options.

CompositionSuper DHA 310 mg
Daily dose : 6 softgels
Number of doses per box : 15
Amount per dose
Standardised fish oil
[50% docosahexaenoic acid (DHA) (around 1,860 mg)
and 10% eicosapentaenoic acid (EPA) (around 258 mg)]
4 320 mg
Other ingredients: D-alpha-tocopherol.
Directions for useSuper DHA 310 mg
Take one or two softgels with each meal
Warning: Product derived from fish. Contains traces of soya.

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