- Has antioxidant, soothing and immunomodulatory effects.
- Neutralises the free radicals, offering relief and protection of the skin.
- Encourages the preservation of skin tissue structure.
Derma Relief is a probiotic formula to help relieve skin problems, by creating a healthy environment for your gut flora and, therefore, reducing inflammation in the layers of your skin.
Derma Relief is aimed at anyone looking for a natural way to relieve and improve their skin problems and at those for whom standard treatments have not worked.
Stubborn skin problems can include:
Derma Relief’s formulation is based on a theory widely-documented in the scientific literature (1): that by taking probiotics, you create a healthy environment for your gut flora and reduce inflammation in the layers of your skin.
DermaRelief contains four strains of probiotic with a dual protective coating enabling them to reach the gut in perfect condition. Designed to colonise the gut, these bacterial strains have been carefully selected for their benefits for the skin, immune system and ability to fight inflammation:
DermaRelief also contains several compounds that support the growth of these probiotics or that act in synergy with them:
Contrary to what you might think, probiotics are not just for preventing or improving gastrointestinal problems. We now know they confer systemic effects and that these effects can benefit the skin if the probiotic strains are selected carefully.
Fabio Meneghin and his research team analysed 37 clinical trials investigating the dermatological potential of oral probiotics: 13 out of 17 were shown to be effective in terms of prevention, while 15 out of 20 displayed therapeutic efficacy (3).
There are at least three mechanisms responsible for the benefits conferred by the probiotics in DermaRelief.
Probiotics help strengthen the intestinal barrier’s impermeability, primarily by increasing secretion of immunoglobulin A (IgA) antibodies, the role of which is to neutralise harmful bacteria and toxins in the intestinal lumen. (4).
Strengthening the intestinal barrier prevents various compounds that exacerbate skin inflammation from passing into the bloodstream.
Probiotics and their derivatives modulate the immune system by activating dendritic cells (5-6), stimulating NK cells (7-8) and inducing T-lymphocyte differentiation.
Dendritic cells and T lymphocytes are indeed instrumental in the improvements observed in the skin following probiotic treatment. Their effects on the immune system produce anti-inflammatory benefits via an increase in production of interleukin 10 (IL10) (9-10), a powerful anti-inflammatory cytokine secreted by the body in response to a number of pathological conditions such as eczema and dermatitis.
This mechanism relates to the capacity of emotional states (such as depression and anxiety) to alter gut microbiota, increase intestinal permeability and promote systemic inflammation.
Lactic probiotics may be able to moderate the release of a neuropeptide (a polypeptide functioning as a neurotransmitter and neuromodulator) called substance P (11). This neuropeptide is released by the nervous system in response to pain, stress, mood problems and anxiety, but it is found abundantly in the skin in atopic dermatitis, eczema and other skin problems (12). By restricting its release, probiotics thus help reduce skin disorders.
Daily dose: 1 stick Number of doses per pack: 30 |
Amount |
Lactobacillus casei CBT LC5 | 1.2 billion CFU |
Lactobacillus rhamnosus CBT LR5 | 0.6 billion CFU |
Lactobacillus plantarum CBT LP3 | 0.6 billion CFU |
Bifidobacterium lactis CBT BL3 | 0.6 billion CFU |
Dextrose | 700 mg |
Polydextrose | 630 mg |
Fructooligosaccharides | 450 mg |
Galacto-oligosaccharides | 100 mg |
Riboflavin | 0.45 mg |
Vitamin C | 25 mg |
DL-alpha-tocopheryl acetate | 8 mg |
Thiamine chloride | 0.45 mg |
Pyridoxamine | 0.45 mg |
Other ingredients: cornflour. |
Polypodium leucotomos Extract is a top quality dietary supplement recognised for its ability to repair, soothe and protect the skin. It is primarily composed of Polypodium leucotomos, a fern that grows in tropical forests. Native to Honduras, this unique plant has a long history of use in traditional South American medicine, practitioners of which were quick to recognise its efficacy at regenerating skin tissue.
The supplement Polypodium leucotomos Extract is designed for anyone who wants to improve the condition of their skin whether they suffer from a skin problem or not.
This tropical fern extract has anti-inflammatory, photoprotective, antioxidant and immunomodulatory properties.
This regenerative and soothing formulation has been carefully developed, drawing on the latest scientific studies which show that this plant extract:
Atopic eczema, or atopic dermatitis, is a very common inflammatory disease characterised by redness and intense itching. One study of 105 child and adolescent sufferers showed that a course of Polypodium leucotomos extract supplements was able to significantly reduce skin inflammation and relieve itching. (1)
Certain molecules in the plant may act by inhibiting the expression of pro-inflammatory cytokines in the skin in the case of eczema, psoriasis and other inflammatory diseases.
As with atopic eczema, many skin diseases (infectious, irritative, allergic …) present with ‘erythematous’ plaques, red patches which turn white when pressed. Polypodium leucotomos is specifically able to prevent this erythema from developing.
Oral supplementation with this fern extract has been observed to reduce phototoxic erythematous reactions and significantly improve skin recovery. (2) (3)
Daily serving: 2 capsules Number of servings per bottle: 45 |
Quantity per serving |
Polypodium leucotomos 4:1 leef extract | 1,000 mg |
Other ingredients: Acacia gum, rice flour. |
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