NADH Supplement - Nicotinamide Adenine Dinucleotide to Restore Energy

NADH, or nicotinamide adenine nucleotide, is an important co-factor which supports the work of enzymes throughout the body. In particular, it plays a vital role in the production of energy within each cell. It also contributes to the production of L-dopa, which is subsequently converted into an important neurotransmitter. You can now enjoy its benefits in supplement form, available to buy at Supersmart.

WHat do studies show about administrating NADH?

Studies have evaluated the potential of NADH capsules in alleviating jet lag, Alzheimer's, Parkinson's disease and chronic fatigue syndrome, as well as its benefits as a nutritional sports supplement.

• To patients with Parkinson's disease, it induced an increase in neurotransmitters. It also generated improvements in motor skills, walking, posture and speech as well cognitive and emotional improvement in some patients.
• To people suffering from depression, it had a beneficial effect in 93% of patients. This is because NADH capsules increase levels of noradrenaline in the brain. It may also be assumed that, because of its participation in the production of the energy molecule ATP, it is able to restore energy to the brain.
• To Alzheimer's patients, it prevented the disease from progressing and improved cognitive and behavioural problems. An increase in brain noradrenaline activity was also observed.
• To long-distance runners and cyclists, it significantly improved their performance and stimulated their mental capacity and alertness.
• To footballers, it increased alertness, concentration and ability to react to stress. Their blood levels of L-dopa and noradrenalin also increased.
• To individuals on a long-haul flight, it counteracted the effects of jetlag and improved their alertness and mental function.

Buy NADH energy support today!

1. Abhirup Das, George X. Huang, Michael S. Bonkowski, Alban Longchamp, Catherine Li, Michael B. Schultz, Lynn-Jee Kim, Brenna Osborne, Sanket Joshi, Yuancheng Lu, Jose Humberto Treviño-Villarreal, Myung-Jin Kang, Tzong-tyng Hung, Brendan Lee, Eric O. Williams, Masaki Igarashi, James R. Mitchell, Lindsay E. Wu, Nigel Turner, Zolt Arany, Leonard Guarente, David A. Sinclair. Impairment of an Endothelial NAD -H 2 S Signaling Network Is a Reversible Cause of Vascular Aging. Cell, 2018; 173 (1): 74 DOI: 1016/j.cell.2018.02.008
2. Yoshino, J., Mills, K. F., Yoon, M. J. & Imai, S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 14, 528–536 (2011).
3. Gomes, A. P. et al. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell 155, 1624–1638 (2013).
4. Braidy, N. et al. Mapping NAD(+) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence. Biogerontology 15, 177–198 (2014).
5. Ying, 2008 W. Ying NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences Antioxid. Redox Signal., 10 (2008), pp. 179-206
6. Gross and Henderson, 1983, C.J. Gross, L.M. Henderson, Digestion and absorption of NAD by the small intestine of the rat J. Nutr., 113 (1983), pp. 412-420
7. Kraus et al., 2014Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity, Nature, 508 (2014), pp. 258-262
8. Costford et al., 2010. Skeletal muscle NAMPT is induced by exercise in humans, Am. J. Physiol. Endocrinol. Metab., 298 (2010), pp. E117-E126
9. Abhirup Das, George X. Huang, Michael S. Bonkowski, Alban Longchamp, Catherine Li, Michael B. Schultz, Lynn-Jee Kim, Brenna Osborne, Sanket Joshi, Yuancheng Lu, Jose Humberto Treviño-Villarreal, Myung-Jin Kang, Tzong-tyng Hung, Brendan Lee, Eric O. Williams, Masaki Igarashi, James R. Mitchell, Lindsay E. Wu, Nigel Turner, Zolt Arany, Leonard Guarente, David A. Sinclair. Impairment of an Endothelial NAD -H 2 S Signaling Network Is a Reversible Cause of Vascular Aging. Cell, 2018; 173 (1): 74 DOI: 1016/j.cell.2018.02.008