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Vinpocetine dietary supplement to support brain function
Vinpocetine dietary supplement to support brain function
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Vinpocetine
Brain nutrition
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24 reviews
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29.00 €(29.51 US$) in stock
Description
Superior quality vinpocetine supplement
  • Derived from vincamine extracted from periwinkle (Vinca minor L).
  • Reviewed in over 700 recent scientific publications.
  • Excellent dose of 45mg of vinpocetine a day.
  • Delivered in vegetarian capsules.
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Vinpocetine Dietary Supplement: Vincamine Derivative - Dosage, Reviews

Vinpocetine 15mg is a dietary supplement containing vinpocetine, a derivative of vincamine extracted from periwinkle (Vinca minor L).

Because of its rheological properties, and action on cerebral blood flow and metabolism, it is primarily used for its neuroprotective effects and is one of the most sought-after supplements for brain nutrition.

Who is Vinpocetine 15mg aimed at?

Vinpocetine 15mg is of potential interest to several groups of people:

  • those with recurrent memory problems;
  • those affected by cerebral dysfunction;
  • those wishing to increase their cerebral metabolism momentarily or permanently;
  • those at high risk of cardiovascular problems;
  • those suffering from presbycusis (age-related hearing loss);
  • those regularly affected by tinnitus.

What benefits are offered by vinpocetine?

A number of studies have demonstrated the positive effects of vinpocetine on cognition, hearing and memory (1-3), with several mechanisms of action identified:

  1. it increases blood flow to the brain (4-6) ;
  2. it facilitates the supply of oxygen and glucose to brain cells (7) ;
  3. it supports energy production in brain cell mitochondria;
  4. it helps inhibit a substance called phosphodiesterase;
  5. it helps increase production of neurotransmitters in the brain.

Two studies have shown that, once ingested, vinpocetine crosses the blood-brain barrier to enter the brain (8-9).

Other research has highlighted its antioxidant (10-11), vasodilatory (12), anti-inflammatory (13-14) and antithrombotic properties (15) which are likely to help reduce the risk of cardiovascular problems.

How should Vinpocetine 15mg be taken?

The amount of vinpocetine used in clinical trials varied from 20mg to 50mg a day, and was ideally spread across three doses. Taking 2-3 capsules of Vinpocetine 15mg (30-45mg) a day is therefore fully consistent with the doses examined.

It’s worth noting that vinpocetine is absorbed best by the body when taken with food(16).

Should I be aware of any contraindications before buying vinpocetine?

Vinpocetine plays a role in inhibiting blood platelets.

It is therefore not recommended for those suffering from bleeding disorders or who have had surgery.
Neither should it be taken alongside drugs or supplements which also affect platelet activity, such as high-dose garlic, ginkgo biloba or vitamin E supplements.

Vinpocetine has been used in many countries for over 30 years, particularly for treating neurological issues relating to cerebrovascular problems such as stroke and ischaemia. No serious side-effects have been found from taking it at therapeutic doses, including long-term use.

Vinpocetine is photosensitive and should therefore be stored away from light.

Finally, it’s worth considering other innovative nootropic supplements such as Sarcosine and Homotaurine.

Note : this product should not be used to replace a varied, balanced diet or healthy lifestyle. Follow the advice on use, the recommended daily dose and the use-by date. Not recommended for women who are pregnant or breastfeeding, or for children under 15. Keep out of young children’s reach. Store in a cool, dry place.

Updated : March 2019

Composition
Daily serving: 3 capsules
Number of servings per bottle: 20
Quantity per serving
Vinpocetine 45 mg
Other ingredients: Acacia gum, rice bran.

Each capsule contains 15 mg pharmaceutical grade vinpocetine.
Directions for use
Take two or three capsules a day, in two or three doses, increasing the dose progressively.
30 mg a day is generally recommended as a maintenance dose.
5
4.8 /5 24 reviews
Description
5
4.5 / 5
Quality
5
4.7 / 5
Value for money
5
4.5 / 5

Reviews 24
Excellent
92 %
Great
4%
Average
0%
Poor
4%
Bad
0%

Rodrigo Rodrigo
5
El producto lo compro para mi madre que ir tiene Alzheimer y parece que ayuda al tema cognitivo ,el producto es de mucha calidad aunque pienso que la enfermedad hace también su camino .
MAZAURIC Danielle
5
j'utilise ce complément depuis longtemps mais la vinca minor a été interdite à la vente en France alors que c'est un régulateur de circulation sanguine neurologique formidable. j'espère que sa teneur en principe actif est maintenu car certain complément vendu maintenant sont dépourvus de sa principale molécule et ne sont plus que des erzats . celui-ci me parait valable.
S. RODRIGUES H.antonio
5
Ok Tudo Bem
BONAU Wolfgang
2
Bewertung ist so niedrig, da Sie nach meinem Verständnis, die Kunden in die Irre führen. Eine Tablette enthält 15mg, auf der Dose steht aber einmal 15 mg, dann 45mg. Für mich persönlich ein Betrug, was mir Kosten und viel Mühe bereitet hat. Diese Mittel wird bei einem Verwandten in einem Heim verwendet, nach Verordnung. Auf einmal passen die Tabletten / Verpackung nicht mehr zusammen. Problem!
Die gleiche Irreführung haben Sie auch bei anderen Mitteln von Ihnen angewendet. Ich bat jetzt meinen Arzt nichts mehr von Ihnen zu verordnen.

C.Marie
5
Bon produit, je sens clairement la différence
PEREZ CASTRO Valle
5
Es maravilloso!!! Desde que lo tomo, han desaparecido las lagunas de nemoria y mi mente fluye perfectamente.
Gina
5
très bon produit
Carol Perry
5
hace tiempo que tomamos este producto y va muy bien
GORSKI Jean Francois
5
correspond à mon attente
Gina
5
POUR MOI CELA ME CONVIENT PUISQUE JE REPASSE UNE COMMANDE
PEREZ CASTRO Valle
5
Empezar a tomarlas , y en pocos días los despistes y la falta de concentración, desaparecen.
References
  1. Kiss B, Szpomy L. On the possible role of central monoaminergic systems in the central nervous systems actions of vinpocetine. Drug Dev Res. 1988;14:263–79.
  2. Shibuya T, Sato K. Effects of vinpocetine on experimental brain ischemia, histological study of brain monoamines. Igaku No Ayumi. 1986;139:217–9.
  3. Nicholson CD. Pharmacology of nootropics and metabolically active compounds in relation to their use in dementia. Psychopharmacology (Berl) 1990;101:147–59
  4. Patyar, S., Prakash, A., Modi, M., Medhi, B., 2011. Role of vinpocetine in cerebrovascular diseases. Pharmacol. Rep. 63, 618–628.
  5. Bonoczk, P., Gulyas, B., Adam-Vizi, V., Nemes, A., Karpati, E., Kiss, B., Kapas, M., Szantay, C., Koncz, I., Zelles, T., Vas, A., 2000. Role of sodium channel inhibition in neuroprotection: effect of vinpocetine. Brain Res. Bull. 53, 245–254.
  6. Zhang, L., Yang, L., 2015. Anti-inflammatory effects of vinpocetine in atherosclerosis and ischemic stroke: a review of the literature. Molecules 20, 335–347.
  7. Szilagyi, G., Nagy, Z., Balkay, L., Boros, I., Emri, M., Lehel, S., Marian, T., Molnar, T., Szakall, S., Tron, L., Bereczki, D., Csiba, L., Fekete, I., Kerenyi, L., Galuska, L., Varga, J., Bonoczk, P., Vas, A., Gulyas, B., 2005. Effects of vinpocetine on the redistribution of cerebral blood flow and glucose metabolism in chronic ischemic stroke patients: a PET study. J. Neurol. Sci. 229–230, 275–284.
  8. Gulyas, B., Halldin, C., Sandell, J., Karlsson, P., Sovago, J., Karpati, E., Kiss, B., Vas, A., Cselenyi, Z., Farde, L., 2002a. PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects. Acta Neurol. Scand. 106, 325–332
  9. Gulyas, B., Halldin, C., Sovago, J., Sandell, J., Cselenyi, Z., Vas, A., Kiss, B., Karpati, E., Farde, L., 2002b. Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine. Eur. J. Nucl. Med. Mol. Imaging 29, 1031–1038.
  10. Deshmukh, R., Sharma, V., Mehan, S., Sharma, N., Bedi, K.L., 2009. Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine – a PDE1 inhibitor. Eur. J. Pharmacol. 620, 49–56.
  11. Herrera-Mundo, N., Sitges, M., 2013. Vinpocetine and alpha-tocopherol prevent the increase in DA and oxidative stress induced by 3-NPA in striatum isolated nerve endings. J. Neurochem. 124, 233–240
  12. Giachini, F.R., Lima, V.V., Carneiro, F.S., Tostes, R.C., Webb, R.C., 2011. Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1. Hypertension 57, 655–663.
  13. Jeon, K.-I., Xu, X., Aizawa, T., Lim, J.H., Jono, H., Kwon, D.-S., Abe, J.-I., Berk, B.C., Li, J.- D., Yan, C., 2010. Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proc. Natl. Acad. Sci. USA 107, 9795–9800.
  14. Medina, A.E., 2010. Vinpocetine as a potent antiinflammatory agent. Proc. Natl. Acad. Sci. USA 107, 9921–9922.
  15. Yi-shuai Zhang, Jian-dong Li, and Chen Yan. An update on Vinpocetine: New discoveries and clinical implications, Eur J Pharmacol. 2018 Jan 15; 819: 30–34.
  16. Lohmann A, Dingler E, Sommer W, et al. Bioavailability of vinpocetine and interference of the time of application with food intake. Arzneimittelforschung. 1992;42:914-917.

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