If you’re still wondering whether to try DermaRelief, here are six reasons that should convince you.

1. Hyperactivity in the skin’s immune system (keratinocytes, dendritic cells and T lymphocytes) is seen in many dermatological conditions (13-16).
2. Intestinal transit problems and diseases such as Crohn’s disease and IBS very often have dermatological manifestations (17-18).
3. In most of the world’s cultures, people have been consuming fermented foods (containing probiotics) for at least 8000 years.
4. It has been shown that diet can help protect skin cells from the inside through a targeted intake of tocopherols and vitamin C in particular.
5. Animals deprived of gut flora are seen to have fewer B and T lymphocytes, dendritic cells and immunoglobulins, and significantly increased inflammation: all of which are corrected by supplementation with probiotics (19).
6. DermaRelief is comprised of four bacterial strains rigorously selected for their probiotic potency, and contains only one natural excipient: corn flour.

Polypodium leucotomos restricts UV’s harmful effects

Polypodium leucotomos’ effects in preventing skin damage are also due to its photoprotective properties – the power to protect the skin from the negative effects of the sun’s rays. This ability may have been acquired in the course of the plant’s evolutionary aquatic-to-terrestrial transition (4)

The fern’s components may act by inhibiting the photoisomerisation and photodecomposition of trans-urocanic acid ordinarily caused by UV exposure. Polypodium leucotomos extract may ultimately result in the strong>inhibition of apoptosis (programmed cell death) caused by the sun’s rays. (5) (6)

An American study from 2015 showed that taking an extract of this plant (in the form of a 240mg supplement, twice a day for 60 days) was an effective way of reducing UV-induced damage. It also confirmed the absence of any contraindications. (7)

Taking a Polypodium leucotomos extract is also beneficial in the treatment of idiopathic photodermatitis: it alleviates polymorphic light eruptions, actinic prurigo and solar urticaria. (8)

It fights skin ageing and protects DNA

Polypodium leucotomos also plays an important role in preventing photoageing. It works, in particular, by strengthening the fibroblasts in skin tissues and supporting keratinocyte proliferation, which delays the appearance of wrinkles and prolongs the skin’s suppleness. (9)

As we know, the sun can cause serious damage by adversely affecting the DNA strands in our cells. Over time, these changes can go on to cause cancer. A course of Polypodium leucotomos can help reduce this risk by protecting the genetic composition of skin cells.

A plant rich in p-coumaric, caffeic and ferulic acids ...

Naturally rich in antioxidants, this plant extract provides an excellent way of fighting the oxidative stress that attacks the body. The compounds it contains include:

• p-coumaric acid
• l'caffeic acid
• l'vanillic acid
• and ferulic acid. (10)

The perfect composition for eliminating reactive oxygen species (ROS)

These various acids help eliminate free radicals naturally (as well as other reactive oxygen by-products such as superoxide anion), all of them unstable molecules which ‘clutter up’ the body, damage cells and proteins, and are a cause of cancer and degenerative diseases. (11) (12)

Our gut flora enables the production of vitamins which the body is unable to synthesise, as well as the digestion of complex molecules, and even supports the efficacy of the immune system. The symbiotic relationship between the various bacterial strains that make up our gut flora has played a key role in the evolution of the human species.

Nowadays however, a number of factors such as over-consumption of ultra-processed foods and excessive use of anti-microbial agents have unfortunately contributed to a profound change in the diversity and quantity of the beneficial bacteria colonising our intestines, a significant development given that women pass their microbiota onto their babies (20). At the same time, the incidence of skin allergies and chronic dermatological conditions is continuing to rise, especially in Western countries.

Probiotic supplementation helps restore the balance of microbiota when it has been disrupted, for example, by antibiotic treatment (21).