CDP Choline Supplement - Cytidine 5-diphosphocholine for Brain Metabolism

Cytidine 5-diphosphocholine (CDP-choline) is an exceptionally bio-available form of choline which readily crosses the blood-brain barrier into the central nervous system, where it is directly incorporated into the phospholipidic fraction of membranes and microsomes, now available to buy in vegetarian capsules at Supersmart.

What are the benefits associated with CDP-choline?

It increases levels of the main neurotransmitters (norepinephrine, dopamine and acetylcholine) and directly improves cerebral metabolism through several mechanisms:

• CDP-choline supports cognitive function and facilitates communication between neurons.
• It supports cerebral metabolism and mitochondrial activity in neurons.
• It activates biosynthesis and maintains the quality of phospholipids which make up a third of all brain tissue.
• It helps maintain memory and cognitive function by supporting healthy levels of acetylcholine as well as activity of the nerves which respond to acetylcholine.

What do studies show about CDP Choline?

A number of human studies evaluating the ability of CDP-choline to halt age-related decline in memory have shown significant results at dosages of between 1000 and 2000 mg a day:

• It is used to help re-absorption of oedema caused by cranial trauma and stroke.
• CDP-choline has been studied, with varying results, for its ability to accelerate recovery in patients suffering from post-traumatic coma and in those with ischemic and thrombotic problems.
• Its neuro-protective power makes it an excellent supplement both for treating chronic cognitive decline associated with ageing and as an adjunct treatment for Alzheimer's and Parkinson's disease. In animal studies, CDP-choline inhibited neuronal degeneration induced by the damaging beta-amyloid protein which is found abundantly in the brains of Alzheimer's patients.

Buy CDP Choline capsules for nootropic benefits.

Other supplements of interest from Supersmart

As well as supplementing with CDP Choline, you may find these other nutritional supplements of interest too.

Discover the properties of Choline Complex, a percursor of acetylcholine that helps to stimulate the body's cognitive abilities.

See also Bacopa monnieri, a nootropic supplement that helps to improve memory, learning capacity and information-processing.

1. Bidulescu, A., Chambless, L. E., Siega-Riz, A. M., Zeisel, S. H., & Heiss, G. (2009). Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) Study. Nutrition Journal, 8(1). doi:10.1186/1475-2891-8.
2. Silveri MM et al. Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy.NMR Biomed. 2008; 21(10):1066-75.
3. McGlade E. et al., Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women Food and Nutrition Sciences. 2012;3:769-773.
4. McGlade E. et al., Cognizin Supplementation on Motor Speed and Attention with adolescent males. Presented June 16 – 19th, 2014 at the American Society of Clinical Psychopharmacology.