N-Acetyl L-Tyrosine is a dietary supplement containing tyrosine, a proteinogenic amino acid produced by the body from phenylalanine.
It plays a role in the production of melanin, a pigment responsible for skin colour, and in regulating mood.
Tyrosine is produced by the body from phenylalanine, the dietary requirements of which have been assessed by the WHO as being 1.5g-2g (1-2). However, when metabolic demand exceeds what can be produced endogenously, tyrosine needs to be obtained at sufficient levels from the diet, as is the case with other amino acids such as taurine, glycine, arginine and proline.
In such – relatively frequent – cases (fatigue, over-training, low mood), tyrosine supplements can be helpful. Tyrosine actually helps to synthesise catecholamines – adrenalin, noradrenalin and DOPA, as well as melanin and thyroid hormones.
Tyrosine is able to cross the blood-brain barrier and reach the brain, where a fraction of it is converted under the action of an enzyme called tyrosine-hydroxylase (4), which is in turn converted into the so-called ‘pleasure’ hormone. Studies show these conversions increase in situations of stress or intense cognitive exercises (5-7). In the medium term, however, stress is known to reduce the level and performance of catecholamines, probably due to the fact that the amino acids that help to produce them become depleted.
A number of pathological conditions are associated with decreased synthesis of catecholamines and the ‘pleasure hormone’ (8-9).
Our team of nutrition experts and scientists has the answers.
N-acetyl L-tyrosine supplements are usually taken by sportspeople to combat fatigue (physical and mental) and to increase resistance to stress. The scientific literature reports no risks associated with such use but does not recommend it for those with thyroid problems.
The recommended dose is around 600mg of tyrosine a day (2 capsules), to be taken at the beginning of the day when the rate of catecholamine synthesis in the brain is at its highest.
This product’s capsules are made of pullulan, a natural polysaccharide obtained by fermenting tapioca or corn. Pullulan contains no animal ingredients and provides an excellent barrier to oxygen, helping to preserve the integrity of the capsule’s ingredients. It is also an eco-friendly alternative to synthetic materials.
Tryptophan is an essential amino acid, and in particular, a serotonin precursor. Unlike tyrosine, tryptophan is found in plant-source foods because animals are not able to synthesise it. However, both these amino acids are involved in producing neurotransmitters, so it is worth considering combining tyrosine supplementation with that of tryptophan.
january 7 2026
It's helping me a bit, I can be more emotionally centered and more stable, it reduces anxiety, let's see in the long term if the effects persist, I'm at the beginning, I use 2 tablets before breakfast.
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october 8 2025
Super product and effective!
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october 2 2025
It seems good to me
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may 14 2025
GOOD PRODUCT
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november 29 2024
product meets my expectations
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Hello Daniel,
Thank you for your feedback regarding the product N-Acetyl L-Tyrosine. Tyrosine is an amino acid that plays a key role in the production of neurotransmitters, such as dopamine and norepinephrine. It can be beneficial in situations of stress, fatigue, or concentration, as it helps support cognitive function and mood.
It is important to note that the effects of supplementation can vary from person to person and may take some time to manifest. If you do not feel immediate effects, it does not necessarily mean that the product is ineffective. I encourage you to continue taking it and observe your sensations over a longer period.
If you have any other questions or if you wish to discuss your experience, please do not hesitate to contact us. We are here to help you!
Best regards,
Gaëlle
Supersmart Customer Service