![Noopept]( "Noopept")
Noopept
This dipeptide, comprising proline and glycine (N phenylacetyl-L-prolylglycine ethyl ester), was developed in Russia and patented in 1995. It is prescribed in Russia and neighbouring countries as a nootropic and neuro-protector.
Noopept, a nootropic substance
Nootropics enable us to adapt better to life’s challenges, by facilitating day-to-day motivation and decision-making and by improving cognitive and neurosensory processes as a whole. They improve neurotransmission quality (gabaergic, cholinergic and glutamergic), facilitate learning and increase the speed at which we process information.
Noopept is a member of the racetam family and shares similar mechanisms of action but is potentially up to 1000 times more powerful than piracetam, which is widely used as an adjunct treatment for chronic cognitive and neurosensory impairment in older people.
Noopept is able to stimulate various receptors - dopaminergic (D2 and D3), cholinergic, nicotinic and serotoninergic, as well as reduce anxiety, stress and irritability, and improve mood and quality of sleep.
Noopept, Neurostimulant and neuroprotective properties
Noopept stimulates the expression of two proteins in the hippocampus - the neurotrophins NGF (nerve growth factor) and BDNF (brain derived neurotrophic factor), involved in the generation and growth of new neurons. This is a highly beneficial property since it helps neurons survive and maintains their activity. Its effect continues even after administration of Noopept ceases.
Noopept also stimulates the glutaminergic receptors AMPA and NMDA which play an essential role in memory and synaptic plasticity.
Noopept thus improves cerebral performance and is used to stimulate intelligence, cognitive function, concentration and focus. It increases learning ability and memory consolidation and restoration as well as logical reasoning.
Studies have shown promising results in relation to Alzheimer’s disease, particularly in terms of repair to damaged cells and certain receptor sites.
One study suggests Noopept may also offer significant benefits to sufferers of Parkinson’s disease, by blocking cytotoxic activity of amyloid oligomers.
In addition, a study on mice showed Noopept to have anti-inflammatory effects linked to its antioxidant properties.
Noopept, an optimal bioavailability
Noopept has excellent bioavailability when taken sublingually, demonstrating immediate efficacy and visible results within just five to seven days of daily use. It easily penetrates the blood-brain barrier and is thus fully active in the brain.
Noopept, very safe
This highly active compound is recommended at doses of between one and three sublingual tablets a day. Noopept is widely documented as safe with mild side effects observed only rarely at high doses (headaches, insomnia, nausea, fatigue).
No dependency or interactions with other supplements or drugs have been identified.
Taking a low dose (10mg-30mg a day) of Noopept sublingually is a completely safe and natural way of improving memory and cognitive function and constitutes a significant aid to coping with day to day stress.
