- Helps reduce inflammation.
- Helps restore joint comfort.
- Standardised to 20% AKBA (the most active principle).
- 50% better absorbed than standard extracts.
Hyaluronic Acid supplement is a high molecular weight sodium hyaluronate, that brings benefits for both improving lubrication of the joints and helping to maintain good hydration in the skin.
Over the past few years, hyaluronic acid has received significant attention from both the medical press and the cosmetics sector. It’s a polysaccharide macromolecule from the glycosaminoglycan family which is abundant in the skin and synovial fluid (the viscous fluid surrounding our joints). Under normal conditions, the human body contains around 12g.
It’s produced by cells called chondrocytes and synoviocytes to increase the viscosity of synovial fluid, which improves the lubrication of the joints. It also helps maintain good hydration in the skin by capturing water and retaining it in the skin’s deeper layers (1). In some cases, it also reduces the concentration of inflammatory mediators and the activity of immune cells.
The viscosity of the gel depends on the chain length of the hyaluronic acid. The higher its molecular weight, the greater the molecule’s capacity for absorbing water. Therefore, with a molecular weight of 1.2 million Daltons, Hyaluronic Acid 150 mg is one of the best sodium hyaluronate supplements available.
Hyaluronic acid is present in the form of sodium hyaluronate (also called hyaluronan) in the synovial fluid surrounding joints. It usually has a molecular weight of more than 1 million Daltons and under normal conditions, is highly concentrated. As a result of its specific structure and considerable size, it can retain enormous amounts of water (up to 1000 times its own weight), and all the nutrients and hydrophilic substances that go with it. It is solely responsible for the viscosity and elasticity of synovial fluid.
In certain disease states, both the concentration and molecular weight of sodium hyaluronate decrease, contributing to an increase in inflammatory processes and adverse effects on cartilage (2).
Studies show that low molecular weight hyaluronic acid molecules have a completely different function in the body: they can activate cascades of molecular events which trigger the release of inflammatory cytokines. Following trauma, enzymes break the hyaluronic acid up into multiple molecules of lower molecular weight which have a pro-inflammatory effect.
These effects are not seen with large hyaluronic acid molecules, which supports the belief that they are not broken down by digestive enzymes before crossing the intestinal barrier.
Daily dose: 2 capsules Number of doses per pack: 30 |
Amount |
High molecular weight sodium hyaluronate | 300 mg |
Other ingredients: acacia gum, rice flour. |
Super Boswellia is a 100% natural Boswellia Serrata supplement for improving comfort of the joints. Its enrichment with active principles (20% AKBA) and superior absorption make it one of the best supplements on the market, along with Joint Support Formula.
Super Boswellia is designed for several groups of people:
Boswellia serrata is a tree indigenous to India, the Middle East and Africa which belongs to the Burseraceare family. The resin it produces is one of the most popular natural health products available today, especially with those plagued by joint problems.
An oleo-gum resin known as ‘olibanum’ or ‘incense’ is produced by resin-secretory structures in the tree, and tapped from incisions made on its trunk. This resin solidifies on contact with air and releases a pleasant scent when burned. It is teardrop-shaped, around 2cm in diameter, amber-brown in colour with a very brittle consistency.
It is held in particular esteem by the world’s principal traditional systems of medicine. In Ayurvedic medicine, it is known as ‘Salaï Guggul’ or ‘Shallaki Guggul’.
Super Boswellia is formulated to contain up to 20% AKBA, a much higher than normal level. It is made from the Boswellia serrata tree, as this is the richest source of AKBA. Extract of Boswellia serrata generally consists of 5-10% essential oil (including primarily α-pinene, α-thuyene, myrcene and sabinene), and also importantly, four boswellic acids including AKBA and KBA, the tree’s major active principles.
The Boswellia serrata tree grows mainly in the dry regions of India, tropical Africa and the southern Arabian peninsula (Yemen, Oman). In summer or autumn, a few months after deep incisions have been made in the tree’s bark, the oleoresin gum is collected. Once it has solidified in the open air, it is scraped off as amber-coloured teardrops and the collected resin is then made into a dry extract and produced in vegetarian capsules. Trees from the Boswellia species cannot go on producing good quality resin indefinitely: after three consecutive years of harvesting, they must be allowed to ‘rest’ for a few years.
Super Boswellia is produced by the Laila Impex Research Centre, in India, an establishment recognised by the country’s Department of Scientific and Industrial Research (DSIR) and affiliated to a number of university programmes.
Boswellia serrata was used by the Persians, Greeks, Romans, Indians, Chinese and other civilisations for ‘purifying the soul of the departed’ during ceremonial rituals, as well as for its medicinal properties. Ayurvedic texts credit its use with a wide range of benefits, especially improving joint health.
These benefits are due to the two ingredients mentioned above, KBA and AKBA. A number of in vitro studies show that KBA and AKBA inhibit 5-lipoxygenase (5-LO), an enzyme which plays a role in inflammation and thus joint discomfort. AKBA is potentially the more effective of the two because of its acetyl group which gives it greater affinity with 5-LO. Other mechanisms of action are also under investigation (TNF, IL-1, MMP3…).
Daily dose : 1 capsules Nombre de doses par boîte : 60 |
Amount per dose |
AprèsFlex™
[Extract of Boswellia serrata standardised to 20 % 3-0-acetyl-11-keto-beta-boswellic acid (AKBA)] |
100 mg |
Other ingredients :Acacia gum, rice flour.
AprèsFlex™, PL Thomas, USA. |
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