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Welcome Shop by health concern Care of joints, bones and muscles UC II® 10 mg
UC II® Supplement
UC II® Supplement
0415UC II® SupplementSize
Sans nano-particulesSans gluten
UC II® 10 mg
Care of joints, bones and muscles
4.6 out of 5
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8 reviews
Customer reviews
55.00 €(64.43 US$) in stock
UC II® is an undenatured type II collagen supplement for joint health.
  • The only patented, and most effective form, of native type II collagen.
  • Good for stemming decreased collagen in cartilage.
  • Improves joint mobility and flexibility.
60 Veg. Caps.
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Man sitting down, holding knee with two hands due to joint pain

UC II® Supplement - Undenatured Type II Collagen for Joint Health

UC II® supplement is a undenatured type II collagen, delivered in vegetarian capsules. Taken orally, UC II® works with the immune system to promote healthy joints through a process called oral tolerance, now available to buy at Supersmart.

This process helps the body differentiate between foreign invaders, such as bacteria or viruses, and beneficial elements such as nutrients.

Why take UC II®?

Type II collagen, a triple helical molecule, is the principal structural protein in cartilage, responsible for its resistance to traction and its endurance.

Sometimes the body's immune system confuses articular type II collagen with a foreign invader and sends antibodies to attack and destroy it, resulting in deterioration of joint flexibility and mobility. When the body attacks itself in this way, it is referred to as an auto-immune disease.

Low doses of UC II® taken orally stop the immune response targeted at the type II collagen in bone joint cartilage, improving joint mobility and flexibility.

What benefits do studies show about type II collagen?

  • Studies from Harvard University Medical School have shown that low doses (10 mg or less) of undenatured type II collagen, derived from chicken cartilage, act in conjunction with the immune system to prevent such attacks on the joints by the body.
  • A study was conducted on 28 patients suffering from severe rheumatoid polyarthritis. Supplementation with undenatured type II collagen for three months produced significant improvements in their condition; four of them were totally cured (Science, 261: 1727-1730, 1993).
  • Following three months' treatment with undenatured type II collagen, 8 out of 10 patients suffering from juvenile rheumatoid polyarthritis saw a decrease in swelling and sensitivity in their joints. (Arthritis and Rheumatism, 39:623-628, 1996).
  • A total of 8 clinical human studies have shown the efficacy of undenatured type II collagen in treating arthritis.
  • UC II® is the only patented form of undenatured (native) type II collagen. The type II collagens usually found in nutritional supplements are denatured or hydrolysed - in other words, their molecular configuration has been altered rendering them inactive. According to David Trentham, a Harvard scientist and world authority on type II collagen, “to be effective, type II collagen must be in its native form”.
  • UC II® also contains small amounts of glucosamine and chondroitin which are equally good for the joints.

UC II® capsules appear to be an excellent solution for stemming decreased collagen in cartilage. There are other supplements available to buy at Supersmart for maintaining joint health such as L-proline, an amino acid which supports the body's natural production of collagen. If you suffer from joint pain, you may find our supplement Palmitoleic acid, an omega 7 fatty acid, known for its pain-relieving benefits.

UC II® is a trademark of Inter-Health N.I. (US Patents 5,645,851,5,637,321,5,529,786,5,750,144 and international patents pending.)

Daily serving: 1 capsule
Number of servings per bottle : 60

per serving

UC-II® (which provides 10 mg of undenatured type II collagen) 40 mg
Other ingredients: Acacia gum, rice flour.
UC-II® - Lonza
Directions for use
Take one capsule with a glass of water, at bedtime on an empty stomach.
4.6 /5 8 reviews
4.8 / 5
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Value for money
4.4 / 5

Reviews 8
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UC II® 10 mg
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