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Melatonin Spray
Melatonin Spray
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Melatonin Spray
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19.00 €(20.01 US$) in stock
Description
Melatonin supplement in spray form for rapid effects
  • Helps cut the time it takes to fall asleep.
  • Also helps to reduce subjective symptoms of jet lag.
  • Molecular structure identical to the natural hormones produced by the pineal gland.
  • Also contains vitamin B6 which plays a role in normal nervous system function, and helps to reduce fatigue and regulate hormone activity.
  • Delivered in spray form for faster, better, sublingual absorption.
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Tired looking man, awake in bed trying to sleep

Melatonin Spray - Easy and Adaptable Melatonin in Spray Form

Melatonin Spray 1mg is a dietary supplement containing melatonin administered in the form of a spray. This innovative delivery method ensures the melatonin is optimally absorbed, making it much easier for it to enter the bloodstream.

It is one of the most popular supplements for combatting strong>sleep problems and for reducing the time it takes to fall asleep.

Who is Melatonin Spray 1mg aimed at?

This supplement can be invaluable for anyone affected by at least one of the following:

  • repeated difficulty falling asleep at a conventional hour;
  • problems getting up in the morning;
  • frequent night waking;
  • waking up too early in the morning;
  • feeling tired on waking;
  • feeling apprehensive about going to bed (stress of not being able to get to sleep);
  • chronic lack of sleep which impairs daily activities;
  • insomnia;
  • muscle or joint pain on waking or at bedtime;
  • jet lag.

What is melatonin?

Melatonin is a hormone naturally secreted by the body as natural light fades. It tells the brain that night is falling and that it’s time to trigger the physiological processes that culminate in sleep.

Sometimes, however, secretion of this hormone is disrupted, for example, when we’re exposed to artificial light late in the evening or when we’re deprived of natural light during the day. If the situation persists, melatonin production can get completely out of control, seriously impairing sleep quality and hastening the development of various sleep problems.

To reset sleep cycles and make it easier to fall asleep, the idea is to supplement with melatonin to replace what the body has failed to produce naturally at the right time. Obviously, this strategy works particularly well for night shift workers, but is also good for those with jet lag or who are experiencing ‘delayed sleep phase syndrome’. Increasingly common, this is characterised by going to bed late, and getting up late. It usually impacts adolescents and young adults, but is affecting more and more people over 50, especially those who live alone, or who are unemployed or retired. Many older people suffer from the reverse – advanced phase syndrome – where they find it hard to stay awake during the evening, and end up waking up in the early hours of the morning, unable to get back to sleep. Several studies have shown melatonin to be highly effective at improving all these ‘time-shift’ problems, much more so, for example, than using eye masks or earplugs.

What benefits are offered by the spray form?

The sublingual spray provides optimal efficacy, enabling the melatonin to be absorbed faster and better than with oral administration, as the active principles go straight into the bloodstream without being digested. It also allows a timed release effect , with its effects lasting several hours, particularly helpful for those who tend to wake in the night or early hours.

How should you take Melatonin Spray 1mg?

Each spray delivers around 1mg of melatonin combined with 1.5mg of vitamin B6. The dose can be easily adapted, depending on your size/build, and especially on how you feel when you wake up: if, after taking it, you find it difficult to wake up in the morning, the dose is a little too high. If, on the other hand, you are still not getting sufficient sleep, you can increase the dose.

It’s best to use the spray half an hour before going to bed. Melatonin receptors are generally more sensitive around 7.00-8.00pm (1).

What other measures can be taken to boost the efficacy of Melatonin Spray?

To make our product even more effective, we’d recommend adhering to the steps below throughout the supplementation period:

1) Review your lifestyle, taking care to avoid frequent changes to your sleep routine, excessive alcohol consumption and smoking, as well as the use of electronic devices in bed (mobile phones, laptops, tablets …) Establish a calming ritual before going to sleep such as listening to soft music (2), reading, or doing yoga or breathing exercises.

2) Restrict intense visual, physical, auditory or mental stimulation in the two hours before bed.

3) Eat dinner at least two hours before going to bed, prioritising foods rich in tryptophan, an amino acid involved in melatonin production which encourages drowsiness. The best sources are seeds, wholegrain rice, dairy products, eggs, pulses, chocolate and brewer’s yeast.

Four good reasons to take melatonin in a spray

  1. Studies show that melatonin’s mechanism of action is very different from that of benzodiazepines. Melatonin induces a state of ‘calm awakeness’ unlike sleeping pills which enforce drowsiness, disrupting both cognitive performance and sleep architecture. Research has shown that once people start taking sleeping pills or benzodiazepines, 89% continue to take them for at least 8 years. This is hardly surprising given that they profoundly change sleep architecture, and also cause genuine dependency.
  2. Sleep problems have probably never been so common as they are today. The latest reports suggest that more than 40% of people in Europe and North America regularly have problems sleeping, and that sleep duration is getting shorter and shorter.Yet sleep is of crucial importance to long-term health, as it affects cognitive faculties, the rebuilding of damaged cells, neuronal synaptic plasticity, the protective capacity of the immune system, the repair of tissues, the efficacy of the endogenous antioxidant system, mental health, maintenance of muscle and bone tissue, etc. Research shows that when 20 year-old men were subjected to 6 nights of only 4 hours’ sleep a night, their blood and cognitive profiles were similar to those of 60 year-old diabetics (memory loss, hypertension, lower insulin secretion).
  3. This time-release form of melatonin not only promotes drowsiness, but also helps reduce the likelihood of waking in the night.
  4. Its innovative delivery form ensures almost instant sublingual absorption, helping to significantly reduce the time it takes to fall asleep.

Are there any side-effects associated with taking Melatonin Spray?

Toxicology researchers investigating a range of different doses (from 1mg to 300mg), have found no particular adverse effects associated with moderate treatment durations (3).

Note: melatonin is less effective at inducing sleep in those who are stressed, who brood over the day’s events, or who are suffering from pain of various kinds. Where this kind of common issue is responsible for sleep problems, it is better to turn to other supplements such as Natural Sleep Formula.

What contraindications are associated with the use of melatonin?

If you’re suffering from a serious disease, you should only use melatonin under medical supervision. Care should also be taken if you’re taking certain drugs: fluvoxamine, anticoagulants and beta-blockers.

It is also essential to avoid driving, or using any potentially dangerous machinery, in the five hours after you take the supplement.

What are the latest findings on melatonin?

No significant side effects with the time-release form of melatonin (2018) (4).
A daily oral dose of around 2mg is generally very well-tolerated, with no rebound or ‘hangover’ effect, and no interaction with medications used to treat hypertension, diabetes and inflammation.

Melatonin, effective for treating primary sleep disorders and those associated with particular neurological conditions (March 2019) (5). Scientists have noted, however, that it may be necessary to conduct research into sleep problems in children.

More melatonin reaches the bloodstream when administered in spray form (2012)(6). Sublingual absorption seems to prevent part of the melatonin being captured by the liver and maximises its entry into the bloodstream.

Melatonin in spray form also helps normalise oral health (2015) (7).

Melatonin activates the genes responsible for repairing DNA damage (2017) (8). A team of researchers recently showed how important it is to sleep at night for significantly reducing the risk of cancer. The study’s authors were investigating night shift workers who had to sleep during part of the day. They observed that not only did these night workers have much lower melatonin levels than day workers, but they also had lower levels of the molecule 8-hydroxygeoxyguanosine (8-OH-dG) in their urine. This was a really interesting discovery as 8-OH-dG reflects the body’s activity in repairing DNA damage caused by reactive oxygen species. The greater the level of 8-OH-dG in urine, the more effective this repair capacity. Night workers appear to be less effective at repairing damage to DNA, damage which over the long term, can lead to cancer, or accelerate ageing.

Composition
Daily dose: 1 spray
Number of doses per pack : 80
Amount per dose
Melatonin 1 mg
Vitamin B6 (pyridoxine HCL) 1.5 mg
Peppermint flavour
Other ingredients : water, glycerine, peppermint flavouring, soya lecithins, sodium benzoate, citric acid.
Directions for use
adults.Take one or several sprays under the tongue, as required, in the evening before going to bed. Contains soya lecithins.
Consult a health professional before taking this product if you have a health problem. Do not take melatonin before driving or using machinery.
5
4.6 /5 19 reviews
Description
5
4.8 / 5
Quality
5
4.8 / 5
Value for money
5
4.7 / 5

Reviews 19
Excellent
68 %
Great
21%
Average
11%
Poor
0%
Bad
0%

Iversen (Luxembourg)
3
Great product. Great quality. Fantastic web partner. Now, does this product work. I guess it will greatly depend on your personal situation. I do not feel to be super responsive to melatonin but I definitely like to use it in synergy with other products and teas.
RIVIERE Louis
4
Très bon..
RENAUD Muriel
4
cela m'aide à dormir
Nikki
5
Super produit. Avec 3 poussees, je dors jusqu‘a 7 heures sans interruption
STEINBACH Lucy
5
Excellent Produits
Client
5
Efficace et mieux que les comprimés que je prenais avant
Marie-Christine DE MARCHI
5
Très satisfaisant
Helmut Schreiber
5
Das Produkt wirkt nicht bei allen in der Familie. Bei einem wirkt es als Einschlafmittel nicht.

SUZANNE BONO
5
Un bon accompagnement pour trouver très rapidement le sommeil.
REINERT Christiane
5
Très bon produit !
Marie
5
Efficace à prendre en complément des comprimés. Pour mon cas.
References
  1. Van den Heuvel CJ, Ferguson SA, Macchi MM, Dawson D. Melatonin as a hypnotic: con. Sleep Med Rev. févr 2005;9(1):71 80.
  2. Trahan, T., Durrant, S. J., Müllensiefen, D., & Williamson, V. J. (2018). The music that helps people sleep and the reasons they believe it works: A mixed methods analysis of online survey reports. PLOS ONE, 13(11), e0206531.
  3. Bonnefont-Rousselot D, Collin F. Melatonin: Action as antioxidant and potential applications in human disease and aging. Toxicology. 28 nov 2010;278(1):55 67.
  4. Quera-Salva MA, Claustrat B. Mélatonine : aspects physiologiques et pharmacologiques en relation avec le sommeil, intérêt d’une forme galénique à libération prolongée (Circadin®) dans l’insomnie [Melatonin: Physiological and pharmacological aspects related to sleep: The interest of a prolonged-release formulation (Circadin®) in insomnia]. Encephale. 2018;44(6):548-557. doi:10.1016/j.encep.2018.06.005
  5. Esposito S, Laino D, D'Alonzo R, et al. Pediatric sleep disturbances and treatment with melatonin. J Transl Med. 2019;17(1):77. Published 2019 Mar 12. doi:10.1186/s12967-019-1835-1
  6. Antonella Natalia Bartoli, De Gregori Simona & al. Bioavailability of a New Oral Spray Melatonin Emulsion Compared with a Standard Oral Formulation in Healthy Volunteers, Bartoli et al., J Bioequiv Availab 2012, 4:7 DOI: 10.4172/jbb.1000120
  7. Reiter RJ, Rosales-Corral SA, Liu XY, Acuna-Castroviejo D, Escames G, Tan DX. Melatonin in the oral cavity: physiological and pathological implications. J Periodontal Res. 2015;50(1):9-17. doi:10.1111/jre.12176
  8. Bhatti P, Mirick DK, Randolph TW, et al. Oxidative DNA damage during night shift work, Occup Environ Med Published Online First:26 June 2017. doi: 10.1136/oemed-2017-104414

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