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Smart Pills + Methylcobalamine
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Smart Pills + Methylcobalamine
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Methylcobalamine
Methylcobalamin is a highly active form of vitamin B12.
  • Indicated for vitamin B deficiency.
  • Has an essential function in a number of vital organs such as the brain.
  • May improve alertness and cerebral protection.
Smart Pills
Smart Pills is an exceptional formulation for stimulating the brain (nootropic)
  • Contains Bacopa monnieri which increases memory and concentration.
  • Contains vitamin B12 which optimises nervous system function and helps reduce nervous fatigue.
  • Contains Ginkgo biloba which increases cerebral circulation and neuronal metabolism.
  • High in caffeine and L-theanine.
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Doctor writing 'Vitamin B12' in a transparent board

Methylcobalamin is formulated from a specific form of vitamin B12 (cobalamin) called methylcobalamin.

The other forms of vitamin B12 are cyanocobalamin and adenosylcobalamin. Methylcobalamin is a highly active form of the vitamin, hence its inclusion in the composition of this new product. Supplementation is particularly useful since vitamin B12 plays a number of roles within the body and is essential for good health. As humans cannot synthesise this B complex vitamin, it must be ingested daily in order to meet the body’s requirements, available to buy at SuperSmart.

What are the benefits of Vitamin B12?

Vitamin B12 is involved in the synthesis, absorption and metabolism of numerous molecules, giving it a key role in the body. In order to offer a high-quality vitamin B12 supplement, this product has been formulated using methylcobalamin. Its recognised activity in the body means it is highly effective at combatting deficiency, amongst other benefits:

  • It supports cell growth and renewal by participating in protein, DNA and RNA synthesis.
  • Helps to maintain healthy skin.
  • Has an essential function in a number of vital organs such as the brain.
  • It is involved in synthesising neurotransmitters as well as maintaining the myelin sheath – the structure that surrounds and protects nerve fibres.
  • Plays a part in lipid metabolism and red blood cell formation.

Providing the benefits of this active form of cobalamin, this supplement contains an optimal 1mg of vitamin B12 per tablet, with a suggested dose of 1 tablet a day, although this can be adjusted in line with your needs and the advice of your therapist.

Why choose methylcobalamin sublingually?

Vitamin B12 sometimes struggles to be absorbed in the intestinal tract, due to gastrointestinal issues, medical conditions, or the use of certain medications.

Our supplement addresses this issue by providing 1 mg of methylcobalamin sublingually. With Methylcobalamin, vitamin B12 is directly absorbed into the bloodstream from the mouth, resulting in enhanced bioavailability.

What do the studies say about Methylcobalamin?

Apart from its use in preventing a lack of vitamin B12, methylcobalamin has also been studied for its potential to improve alertness and cerebral protection. Research has focused in particular on the pharmaceutical benefits of methylcobalamin for preventing neurological problems. Ultimately, such research aims to find effective treatments for neurodegenerative diseases. Initial results suggest that methylcobalamin may act in the brain by:

  • Protecting it from the toxic effects of glutamate, nitric oxide and low oxygen and blood sugar levels.
  • Promoting nerve regeneration which could help slow down the progress of neurodegenerative diseases.
  • Relieving symptoms of facial paralysis.
  • Boosting the activity of natural killer cells and T lymphocytes.
CompositionMethylcobalamine
Daily serving: 1 tablet
Number of servings per bottle: 100
Quantity per serving
Methylcobalamine 1 mg
Other ingredients: Acacia gum, sorbitol, mint essential oil.
Directions for useMethylcobalamine
Take one sublingual tablet a day for preventive purposes, or more if advised by your therapist.
Man's eye looking focused and alert

Smart Pills is a supplement designed to optimise brain function and promote mental efficiency. It is formulated from six different ingredients, including two renowned natural nootropics, Bacopa monnieri and Ginkgo biloba, vitamin B12 - now scientifically recognised as playing a key role in the nervous system, caffeine, taurine and theanine.

The combined scope of their effects enhances well-being and cognitive performance: memory, cerebral microcirculation, mental effort … They work symbiotically to provide the extra boost we need to be more focused and productive.

Who is Smart Pills aimed at?

Smart Pills is for anyone looking to:

  • Maximise their motivation.
  • Respond to cognitive challenges.
  • Improve their mood.
  • Regain greater work efficiency.
  • Achieve ‘flow’, the mental high characterised by deep concentration and total immersion in an activity.
  • Become more effective.
  • View tasks to be accomplished in a clear-headed way (mental clarity).

When is a good time to take Smart Pills?

  • When revising for an exam and during the exam itself.
  • When your workload is particularly heavy.
  • On occasions that demand intense mental effort.
  • Before a stressful event such as an oral presentation, competition, job interview, etc.
  • When you’re finding it hard to find motivation.
  • When you’re mentally fatigued.
  • When you want to break bad habits of procrastination and inattentiveness.
  • When you need to take an important decision.

More generally, Smart Pills can be taken when you need a little boost or an extra level of concentration. You can take one capsule in the morning or before periods of prolonged work and concentration.

There’s also nothing to prevent you from taking it every day for extended periods.

What’s in Smart Pills?

Smart Pills contains five main ingredients, all chosen for their scientifically documented effects and absence of toxicity. As always, SuperSmart has taken the utmost care to use only the highest quality raw materials for each of these ingredients.

smartpills

Extract of bacopa monnieri standardised to 20% bacosides

The benefits of Bacopa monnieri are well-established in terms of improving the cognitive system and memory (1-6), as well as visual perception, attention and language (verbal understanding and vocabulary) and reducing impulsivity (7-8), improving concentration and reasoning (9), as well as alertness and speed of information-processing (10), associative memory (11), retention of new information (12) and even reducing the tendency to make mistakes (13-14).

Its principal chemical components are triterpene saponins (bacoside A1, bacoside 13, bacopasaponins, jujubogenin), cucurbitacins, monnierasides, flavonoids (luteolin and quercetin), alkaloids and coumarins.

Effects have been reported in both adults and children, healthy or otherwise (15), as a result of its different mechanisms:

1) Improvement by bacosides of transmission of nerve impulses. These compounds repair damage to neurons by inducing kinase activity and neuron synthesis, and by restoring synaptic activity (16). They exert antioxidant effects at several levels in all areas of the brain, particularly in astrocytes and fibroblasts where they protect against damage to DNA (17).

2) Involvement in the GABAergic system (18).

3) Effect on glutamatergic transmission (19-20) (lowering glutamate levels).

Our extract of Bacopa monnieri is standardized to 20% of bacosides, the most active ingredients of the plant.

L-theanine extracted from green tea

This is an amino acid found in green tea and certain types of mushroom. A number of preliminary studies have suggested it has a relaxing effect on the nervous system (21-22).

It may explain why drinking green tea every day helps to maintain mental alertness and improve cognitive performance (23) and memory. In research conducted in 2014, improved connections between neurons (called synapses) were observed in green tea consumers compared with controls (24). It also appears to stimulate blood flow in the brain (25).

Taurine

This is one of the most abundant free amino acids in the body: it is present in almost all tissues, particularly excitable tissues such as the muscles, retina and nervous system.

The body is able to synthesise taurine itself in the liver and brain, but additional intake from the diet is necessary to prevent deficiency (26). Requirements for taurine are estimated to range from 40mg to 400mg a day depending on various parameters.

Taurine has excellent bioavailability when ingested: it rapidly enters the bloodstream, crossing the blood-brain barrier with the aid of specific carriers to reach the brain parenchyma where it joins endogenously produced taurine.

It is concentrated in synapses in certain areas of the cerebral cortex where it acts as an inhibitory transmitter, preventing over-stimulation caused by high levels of amino acids (27). It also plays a role in long-term potentiation (LTP) – the significant and sustainable increase in synaptic efficacy – via induction of a cascade of molecular events.

Vitamin B12 (methylcobalamine)

Methylcobalamine participates in neurotransmitter synthesis and helps maintain the myelin sheath in order to preserve the efficacy of nerve fibres.

Recent studies have shown its benefits in increasing alertness and preventing various neurological problems. It is widely recognised for optimising nervous system function and helping to reduce nervous fatigue.

As the body is unable to produce methylcobalamine, it has to be obtained from the diet. However, since it is available in very few foods and high oxidative stress levels increase the body’s requirements for vitamin B12, nutritional supplementation is an increasingly popular option.

Caffeine (anhydrous)

Present in tea and coffee, caffeine is an alkaloid from the methylxanthine family. It is rapidly metabolised by the body and deployed in all tissues including in the brain.

Peak blood concentration is reached within 60 minutes of ingestion and it takes at least three hours for the body to eliminate one half of a dose.

Evidence from dozens of studies, along with individual everyday use, proves beyond doubt that caffeine stimulates the central nervous system, attention, creativity, and mental activity, and helps counter drowsiness. However, it also influences thought development (cognition) by reducing reaction time (31), improving the execution of simple tasks, facilitating learning tasks (32) and improving the ability to retain information useful for accomplishing future tasks (33).

Extract of Ginkgo biloba

For close to 2800 years, we’ve known about the medicinal properties of Ginkgo biloba, an ancient tree that has existed for some 300 million years. It is the leaves which are most highly prized because of their rich content in terpenes, particularly ginkgolides and bilobalides, as well in various polyphenol and flavonol compounds.

Extracts of Ginkgo biloba influence neuronal metabolism by improving the capture of glucose and oxygen. This is due to the action of bilobalides on the mitochondria, the small organelles involved in the conversion and use of energy. This same compound also prevents lipid peroxidation in the brain with the help of ginkgolides, by increasing the activity of glutathione transferase, an endogenous antioxidant. This effect is enhanced by flavonoids which protect brain cells from free radicals (34).

Updated: 30/03/2018

Notes

This product should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. It’s important to follow the guidelines on how to take it and the recommended dose, and to use it by the ‘best before’ date. It is not recommended for women who are pregnant or breastfeeding, or for children under 15. Keep out of children’s reach. Store in a cool, dry place.

Buy Smart Pills capsules to boost your brain activity.

CompositionSmart Pills
Daily dose: 3 capsules
Number of doses per pack: 60

Amount
per dose

Bacopa monnieri standardised to 20% bacosides 750 mg
L-theanine 200 mg
Taurine 200 mg
Ginkgo biloba standardised to 24% ginkgoflavonglycosides and 6% terpene lactones 180 mg
Anhydrous caffeine 100 mg
Methylcobalamine 1 mg
Other ingredients : acacia gum.
Directions for useSmart Pills
Adults. Take 3 capsules a day.

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