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Welcome Shop by health concern Digestion and oro-gastro-intestinal health Candalb
Candalb Supplement
Candalb Supplement
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Candalb
Digestion and oro-gastro-intestinal health
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44.00 €(44.35 US$) in stock
Description

100% natural treatment for eradicating the Candida albicans yeast

  • Contains 4 probiotic strains selected to restore balance to the microbiota and curb the growth of pathogens.
  • Contains caprylic acid, a totally natural, medium-chain fatty acid (MCT) able to break up the cell walls of the Candida albicans yeast.
  • Contains arabinogalactan prebiotic fibre extracted naturally from larch.
  • Enriched with inulin to maximise the probiotics’ survival as far as the gut.
  • Delivered in the form of stomach acid-resistant DR caps™ capsules to maximise the probiotics’ chances of surviving as far as the gut (also delivered temporarily in the form of vegetarian capsules).
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Candalb Supplement – Natural Formula for Healthy Intestinal Flora

Candalb is a dietary supplement designed to naturally help combat growth of the Candida albicans and Candida glabrata yeasts, alongside medication. As a result of its high content of caprylic acid,specific probiotics, prebiotics and serrapeptase, it helps to restore internal balance.

What is Candida infection?

Yeasts from the Candida genus are organisms which are naturally present in the digestive tract, the oral cavity and the reproductive system. They are not usually pathogenic, because they are kept in check by the balance between the various microorganisms in the microbiota (1). However, when an imbalance exists, they can become formidable pathogens, capable of infiltrating various tissues and organs (2). They are said to be ‘opportunist’. The Candida albicans and Candida glabrata yeasts are the most common opportunist microorganisms in the human body (3).

Caused primarily by Candida albicans, vulvovaginal candidiasis is one of the most common gynaecological infections, with one in two women thought to be affected (4). These infections usually appear in the second half of the menstrual cycle in women of child-bearing age.

Candida infections typically develop in two stages:

  1. Colonisation, which is normally restricted by the protective effect of saliva and mucus (5). The yeasts proliferate abnormally, and attach themselves in large numbers to a flat surface (usually the mucosa), forming a biofilm – a kind of barrier formed from a highly-structured cluster of various cells and proteins. This biofilm makes them more resistant to natural anti-fungals, and enables them to survive in what would normally be a hostile environment for them (6). The cells in this biofilm develop and become more complex: some take a filamentous form, others a cylindrical or ellipsoidal one. These cells are attached to each other, forming a dense, three-dimensional structure, and a veritable reservoir of germs, difficult for either the immune system or medication to neutralise (7).
  2. Invasion of the mucosa, facilitated by a lack of cellular immunity (8). The biofilm formation is accompanied by two invasive developments: at the top of the structure, cells disperse to form new biofilms elsewhere in the body, while filamentous cells penetrate the various layers of the epithelial cells that form the mucosa (9). Unchallenged, the latter will go on to reach various areas of the body via the bloodstream .

What are the symptoms of candida?

Symptoms depend on where the colonisation takes place. If it’s in the oral cavity or oesophagus, the main symptoms will be:

  • thrush on the tongue, palate and gums (creamy white patches, firm or joined together, sticking to mucous membranes) ;
  • redness on the tongue and oesophagus.

When colonisation is in the genital area:

  • intense burning in the vulva;
  • itching;
  • a whiteish discharge;
  • redness on the penis, usually in the balano-preputial fold (between the glans and the foreskin).

In most cases, candida resolves satisfactorily but recurrent infections are frequent. Sometimes it crosses the mucous membranes, temporarily spreading throughout the body, and secreting pathogenic molecules (79 known toxins) likely to further weaken the immune system and cause various problems (severe fatigue, repeated digestive problems, sleep issues, stomach pain …).

What is in Candalb, the anti-Candida supplement?

The supplement Candalb has been developed in line with the latest scientific research. It contains:

A specific blend of probiotics (Lactobacillus acidophilus La-5, Bifidobacterium lactis, Lactobacillus rhamnosus, and Latobacillus plantarum). A number of clinical studies have demonstrated the powerful anti-fungal activity of lactobacillus strains against theCandida albicans biofilm (9). In one such study, Lactobacillus rhamnosus was found to impede the growth, morphogenesis (the stage at which cells become filamentous) and adhesion to mucosa of Candida yeasts. Probiotics may also help to rebalance the gut and vaginal microbiota in general (10).

Caprylic acid, a medium-chain fatty acid (MCT) widely used to stem the spread of Candida albicans. It is recommended in the book Vaincre la candidose (Beating candida) by Leon Chaitow and Simon Martin. It is mainly found in mammalian milk, plant oils such as coconut, and in certain seeds (11). Several in vitro studies (12-14) have demonstrated caprylic acid’s anti-candida activity. It may also help to stem the expansion of the above-mentioned biofilm and filamentous growth by modulating the expression of certain genes.

Extract of Western larch (Larix occidentalis) standardised to 85% arabinogalactans. These are a type of soluble fibre known for supporting the digestive system and immune response.

Serrapeptase (5mg or 10,000 IU), a proteolytic enzyme which helps to reduce toxins and dissolve the dead cells responsible for inflammation (15). It should not be combined with natural anticoagulant remedies such as turmeric, garlic or omega-3 supplements.

Not content with having selected freeze-drying for our probiotic supplements, SuperSmart has also added a natural, protective ingredient: inulin. Naturally extracted from chicory root, this non-digestible carbohydrate also stimulates the growth of probiotics once in the gastrointestinal tract (16).

How should Candalb be taken?

With a large glass of water, on an empty stomach or at least two hours after food.

The best way of eliminating this stubborn yeast is to both tackle it with suitable treatments and at the same time, restore your own body’s regulating abilities. Here are some well-documented ways of maximising your chances:

  1. avoid high-sugar foods and those containing nutritional yeasts (Candida albicans loves sugar);
  2. try a lapacho infusion made from the inner bark of the Pau d’arco tree, traditionally used to fight yeast infections (candida);
  3. familiarise yourself with essential oils, especially oil of oregano, clove and cinnamon, all of which are highly relevant, according to Dr Eric Lorrain in his book En finir avec la candidose (Put an end to candida).

Who is most at risk from candida?

  • Anyone who thinks they might have compromised immunity.
  • Those with nutritional deficiencies (especially in vitamins A, B, and C, zinc and iron).
  • Those with a diet too high in carbohydrates.
  • Diabetics, particularly when the diabetes is not well-controlled (17-18). Chronic hyperglycaemia is associated with dysfunction of immune cells called granulocytes, and as a result, reduced cellular immunity.
  • Those who’ve been on antibiotics or other drugs that disrupt microbiota balance. Antibiotics upset the gut flora and facilitate colonisation of the mucosa by Candida albicans.
  • People with a history of gastric surgery.
  • Those suffering from stress (physical and/or emotional), mineral deficiencies (zinc, copper, iron, manganese, etc) and who are physically inactive.
  • Those aged over 65(19-21), because of reduced immune system efficacy and because they often wear dentures.
  • Those suffering from xerostomia, who do not produce sufficient amounts of saliva.

Does Candalb Forte need to be kept refrigerated?

It is best stored at a low temperature with low humidity to ensure the viability of as many probiotic bacteria as possible.

However, storing it at room temperature for a few weeks will only cause a slight reduction in viable bacteria. This is because of the addition of the natural ingredient inulin, which specifically helps to increase the probiotics’ survival when stored at less-than-ideal temperatures.

Composition
Daily serving: 2 capsules
Number of servings per bottle: 30
Quantity per serving
Lactobacillus acidophilus La-5 5,4 MD CFU
Inulin 60 mg
Sodium caprylate 518.75 mg
Arabinogalactan (extracted from Larix occidentalis) 60 mg
Mixture :
Bifidobacterium lactis (LMG 18314) 33 %, Lactobacillus rhamnosus (LMG 25626) 33 %, Lactobacillus plantarum (LMG 26367) 33 %
5 MD CFU
Serratia peptidase (gastroresistant fine granules) of Serratia peptidase 2000 units/mg) 5 mg
Other ingredients : acacia gum.
Directions for use
Adults : take two capsules in a single dose with a main meal, every day for a month. Repeat as necessary.
Once opened, keep refrigerated.
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References
  1. Sardi, J. C. O., Scorzoni, L., Bernardi, T., Fusco-Almeida, A. M., and Mendes Giannini, M. J. S. (2013) Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options. J Med Microbiol 62: 10–24
  2. Manzoni, P., Mostert, M., Leonessa, M. L., Priolo, C., Farina, D., Monetti, C., et al. (2006) Oral Supplementation with Lactobacillus casei Subspecies rhamnosus Prevents Enteric Colonization by Candida Species in Preterm Neonates: A Randomized Study. Clin Infect Dis 42: 1735–1742.
  3. Brunke, S., and Hube, B. (2013) Two unlike cousins: Candida albicans and C. glabrata infection strategies. Cell Microbiol 15: 701–708.
  4. Foxman, B., Muraglia, R., Dietz, J.-P., Sobel, J. D., and Wagner, J. (2013) Prevalence of Recurrent Vulvovaginal Candidiasis in 5 European Countries and the United States. J Low Genit Tract Dis 17: 340–345.
  5. Underwood JA, Williams JW, Keate RF. Clinical findings and risk factors for Candida esophagitis in outpatients. Dis Esophagus 2003;16:66-9.
  6. Hofs, S., Mogavero, S., and Hube, B. (2016) Interaction of € Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota. J Microbiol 54: 149–169.
  7. Chandra J, Kuhn DM, Mukherjee PK, Hoyer LL, McCormick T, Ghannoum MA. Biofilm formation by the fungal pathogen Candida albicans: development, architecture, and drug resistance. J Bacteriol. 2001; 183:5385–5394.
  8. Baehr PH, McDonald GB. Esophageal infections : Risk factors, presentation, diagnosis, and treatment. Gastroenterology 1994;106:509-32.
  9. Ghosh S, Navarathna DHMLP, Roberts DD, Cooper JT, Atkin AL, Petro TM, et al. Arginineinduced germ tube formation in Candida albicans is essential for escape from murine macrophage line RAW 264.7. Infect Immun. 2009; 77:1596–1605.
  10. Rodnei Dennis Rossoni et al, Junqueira (2018) Antifungal activity of clinical Lactobacillus strains against Candida albicans biofilms: identification of potential probiotic candidates to prevent oral candidiasis, Biofouling, 34:2, 212-225, DOI: 10.1080/08927014.2018.1425402
  11. Parolin, C., Marangoni, A., Laghi, L., Foschi, C., Nahui Palo- ~ mino, R. A., Calonghi, N., et al. (2015) Isolation of Vaginal Lactobacilli and Characterization of Anti-Candida Activity. PLoS ONE 10: e0131220
  12. Marten B, Pfeuffer M, Schrezenmeir J: Medium-chain triglycerides. Int Dairy J 2006;16:1374–1382.
  13. Ashwini Jadhav et al. The Dietary Food Components Capric Acid and Caprylic Acid Inhibit Virulence Factors in Candida albicans Through Multitargeting, JOURNAL OF MEDICINAL FOOD J Med Food 00 (0) 2017, 1–8 # Mary Ann Liebert, Inc., and Korean Society of Food Science and Nutrition DOI: 10.1089/jmf.2017.3971
  14. Takahashi M, Inoue S, Hayama K, Ninomiya K, Abe S: Inhibition of Candida mycelia growth by a medium chain fatty acids, capric acid in vitro and its therapeutic efficacy in murine oral candidiasis. Med Mycol J 2012;53:255–261.
  15. Bergsson G, Arnfinnsson J, Steingrı´msson O´ , Thormar H: In vitro killing of Candida albicans by fatty acids and monoglycerides. Antimicrob Agents Chemother 2001;45:3209–3212.
  16. Shivani Bhagat, MonikaAgarwal, Vandana Roy. Serratiopeptidase: A systematic review of the existing evidence, International Journal of Surgery, Volume 11, Issue 3, April 2013, Pages 209-217, https://doi.org/10.1016/j.ijsu.2013.01.010
  17. Prebiotic capacity of inulin-type fructans. Kolida S, Gibson GR. J Nutr. 2007 Nov;137(11 Suppl):2503S-2506S. Review.
  18. Bartholomew GA, Rodu B, Bell DS. Oral candidiasis in patients with diabetes mellitus : A thorough analysis. Diabetes Care 1987;10:607-12.
  19. Yakoob J, Jafri W, Abid S, et al. Candida esophagitis : Risk factors in non-HIV population in Pakistan. World J Gastroenterol 2003;9:2328-31.
  20. Mimidis K, Papadopoulos V, Margaritis V, et al. Predisposing factors and clinical symptoms in HIV-negative patients with Candida oesophagitis : Are they always present ? Int J Clin Pract 2005;59:210-3
  21. Weerasuriya N, Snape J. A study of Candida esophagitis in elderly patients attending a district general hospital in the UK. Dis Esophagus 2006;19:189-92

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