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Red Propolis + Organic MycoComplex
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Red Propolis + Organic MycoComplex
Immune system, fatigue and infections
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Organic MycoComplex
Organic MycoComplex is a super-complex of 7 medicinal mushrooms – Shiitake, Chaga, Reishi, Maitake, Cordyceps, Polypore and Agaricus.
  • Contains extracts of organic mushrooms.
  • Standardised to 30% polysaccharides and 0.7% triterpenes.
  • Extracted by enzymatic fermentation of chitin walls.
  • Boosts the immune system and fights fatigue.
  • Powerful anti-tumour, antioxidant, ant-infectious and anti-inflammatory properties.
  • Enriched with prebiotics, ginseng and selenium.
Red Propolis
Red Propolis is the rarest, wildest and most effective type of propolis

  • Red propolis harvested in Brazil and extracted in France.
  • Produced by bees from the plant species Dalbergia ecastaphyllum.
  • Contains more than 300 synergistic antioxidant and immune-stimulant compounds.
  • Provides the body with ‘natural weapons’ to resist infection of all kinds.
  • Helps increase immune capacity.
  • Fights oxidative stress and alleviates symptoms of the menopause.
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Sliced and powder mushrooms

Organic MycoComplex is an exceptional formulation containing extracts of seven medicinal mushrooms (Inonotus obliquus, Trametes versicolor, Cordyceps militaris, Ganoderma lucidum, Agaricus brasiliensis, Lentinula edodes and Grifola frondosa), with a guaranteed concentration of at least 30% polysaccharides and 0.7% triterpenes, now available to buy at Supersmart.

Mushrooms are miniature pharmaceutical factories, and of the thousands of mushroom species in nature, our ancestors and modern scientists have identified several dozen that have a unique combination of talents that improve our health“, Paul Stamets, leading American mycologist and member of the editorial board of The International Journal of Medicinal Mushrooms.

SuperSmart has chosen seven of these species for its brand-new nutritional formulation which offers exceptional benefits. Produced using an enzyme mixture and the latest advances in microbiology, Organic MycoComplex optimises the activity and bioavailability of the best mushroom species available in the field of nutritional supplementation. So you can be among the first to benefit from some of the most promising medicines of the future ...

Who is Organic MycoComplex designed for?

This formulation is primarily for people suffering from fatigue, whatever the cause. It is also for those who:

  • Wish to benefit from the ‘super-tonic’ and protective effects of mushrooms.
  • Want to protect their body using natural substances.
  • Are lacking in energy.
  • Are suffering from various types of pain.
  • Have intestinal disorders.
  • Are receiving intensive anti-cancer treatment.
  • Have a fragile immune system.

What is in Organic MycoComplex?

Organic MycoComplex contains extracts of seven different organically-grown mushrooms.

Maitake (Grifola frondosa)

Prior to its cultivation in 1979, maitake was known as the dancing mushroom because it’s said that those who found it growing wild danced with joy at their discovery. It is a highly-valued mushroom which contains a number of polysaccharides. Among its properties, scientists have shown that it’s able to:

  • Lower blood glucose levels (1-2).
  • Reduce blood pressure.
  • Reduce blood cholesterol levels.
  • Stimulate the activity of certain immune cells (3).

Active compounds: primarily the polysaccharides beta 1-6-glucans, alpha-glucans and MZF (Maitake Z-fraction) (4). Studies have shown that these compounds encourage maturation of dendritic cells and help activate various cell effectors such as macrophages, Natural Killer cells, T lymphocytes, interleukin-1 and superoxide anion (5). Other studies have demonstrated a blood glucose-lowering effect: by acting on insulin receptors, alpha-glucan polysaccharides may increase insulin sensitivity in cells and improve insulin resistance in peripheral tissues. They also act against tumours by upregulating expression of a pro-apoptosis gene (BAK-1) (6).

Attention: The extracts do not all have the same proportion of active principles nor the same concentration. This product should not be taken alongside anti-diabetes medication.

Reishi (Ganoderma lucidum)

This ‘mushroom of immortality’ has enjoyed exceptional renown in Asia for more than 2000 years. There are references to it in the oldest written Chinese pharmacopoeia (dating back to 56BC) and it was probably being used by Asian populations for thousands of years before then.

It’s very rarely found growing wild, but cultivation became possible after the 1970s under highly specific laboratory conditions. This was truly liberating given the significance of its therapeutic properties, which include the ability to:

  • Lower blood cholesterol levels.
  • Stimulate certain immune cells (7).
  • Reduce inflammation (8).
  • Increase antioxidant capacity (9).
  • Protect the liver.
  • Combat cell proliferation(10-13).
  • Boost the body as a whole and maintain optimal health.

Active compounds: these are primarily beta-glucan polysaccharides and triterpenes. The latter reduces the expression of metalloproteins and prevent cell proliferation by suppressing the expression of Vascular Endothelial Growth Factor (VEGF) and upregulating the expression of connexin 43 (14).

Attention: In traditional Chinese medicine, only the flesh of the mushroom is used (ie, the cap and the stalk) but several supplement manufacturers use the mycelium, a less expensive part of the mushroom which does not offer the same benefits.

Shiitake (Lentinula edodes).

Used for over 2000 years for its medicinal properties, shiitake is probably the most widely-studied mushroom for its anti-cancer virtues. It helps to:

  • Reduce levels of LDL cholesterol transporters (15).
  • Boost the immune system against cancer and infections (16).
  • Promote healthy arteries.

Active compounds: Its properties come from two compounds in particular, lentinan (1-3 beta-D-glucan) (17) and eritadenine. These compounds do not have a direct cytotoxic effect on tumours but they modify the body’s biological response. Increases have thus been observed in secretion of interleukin (IL-2) and additional activation of macrophages.

Royal sun mushroom (Agaricus brasiliensis).

Native to Brazil, but also widely-found in Asia, the royal sun mushroom is highly valued for its delicious, almond-flavoured flesh. It also offers significant benefits:

  • It improves quality of life for cancer sufferers (18-20).
  • It supports liver function (21)
  • It improves insulin resistance (22-24).
  • It reduces blood glucose levels.
  • It reduces blood cholesterol levels (25).
  • It has an oestrogen-like effect.

Active compounds: brefeldin A, ergosterol (the primary constituent), blazeispirol A (produced by fermentation of the mushroom), agaritine and polysaccharides. These compounds activate a number of molecular cascades that lead to apoptosis, the programmed death of abnormal cells. They also play a role both in activating NK cells, normal cell signalling and supporting damaged blood vessels (26).

Chaga (Inonotus obliquus).

Unlikely as it might seem, this increasingly popular mushroom is nothing more than a parasite of the birch tree. Yet behind this inauspicious exterior lies a powerful health-boosting mushroom with a delicate flavour. With blood glucose-lowering properties, it has been used for centuries in Asia and Russia to calm inflammation and optimise digestion. Interest in chaga intensified dramatically when in 2011, a team of scientists from Queensland University of Technology discovered that in certain cases, it could reverse tumours in rodents, with no apparent side effects. Researchers are currently investigating its potential to:

  • Boost antioxidant capacity (27).
  • Reduce inflammation and fatigue (28).
  • Relieve pain (29).
  • Stimulate the immune system (30).
  • Slow down the progress of cancer (31-32).

Active compounds: inotodiols (triterpenoids), oxalic acid, gallic acid, protocatechuic acid and p-hydroxybenzoic acid. Terpenoids are responsible for the anti-diabetes effects by inhibiting alpha-glucosidase, while the anti-fatigue effects come more from polysaccharides which increase glycogen in the muscles and liver, while reducing levels of nitrogen in urea and restoring those of endogenous antioxidants (glutathione, superoxide dismutase) (33). Its pain-relieving properties are due to inhibition of nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Last but not least, its anti-proliferative properties are the result of modulated expression of caspase apoptosis-triggers by lignin derivatives.

Attention: Its use is contra-indicated in type 1 diabetics, those with coagulation disorders and those who have had a transplant.

Organic MycoComplex also contains extracts of polyporus versicolor, and cordyceps (effective at stimulating poor sexual function and restoring energy (34)), as well as selenium, prebiotic fructo-oligosaccharides and an extract of ginseng, the essential plant-source aid for stimulating the immune system and fighting fatigue.

What are the benefits of taking Organic MycoComplex?

Europeans and North Americans tend to be wary of mushrooms because of their potential toxicity. But they are missing out. East Asian populations have always regarded them as an essential part of their pharmacopoeia, while the scientific community continues to link them to an increasing number of therapeutic benefits. It now seems that mushrooms’ range of activity is huge: they are in a therapeutic class of their own, with an almost unrivalled wealth of nutritional virtues.

Organic MycoComplex addresses several areas of health:

Gut health. Mushrooms contain a large amount of insoluble dietary fibre which increases the weight and volume of stools, facilitating their elimination from the body and preventing constipation. They also contain non-digestible sugars which nourish ‘friendly’ bacteria in the gut and bowel, helping to strengthen the intestinal barrier and reduce systemic inflammation.

The field of oncology. Two types of compound are responsible for the anti-tumour properties of mushrooms: polysaccharides and lectins. Polysaccharides are long chains of simple sugars. They induce production of cytokines such as interferon or IL-2 which activate the proliferation of a number of immune cells and boost the destruction of foreign elements. Lectins are carbohydrate-binding proteins which induce apoptosis in abnormal cells including tumour cells.

The field of cardiology. As a result of its various ganoderma, coumarin and polysaccharide compounds, mushrooms help lower cholesterol and triglyceride levels, two factors associated with cardiovascular problems.

The immune system. This is mushrooms’ ‘strongest suit’. Most of them have properties that strengthen weakened immune systems, particularly as a result of radiotherapy or infections. The polysaccharide compounds increase numbers of macrophages, NK cells and cytotoxic T lymphocytes.

Activity against free radicals. Mushrooms have certain antioxidant properties and thus help combat the oxidative stress involved in many health problems. When the body is exposed to high levels of free radicals, normal detoxification processes are unable to function properly which leads to a state of pathological imbalance.

Stress. Like ginseng and ashwagandha, mushrooms are considered to be adaptogens, helping to restore and balance various parameters associated with stress. They act rather like spark plugs, improving the body’s adaptation to stress and acting as an energy potentiator of the adrenal system

Did you know?
Mushrooms, which are known scientifically as Eumycetes, are phylogenetically closer to us than to plants.

Five reasons to choose Organic MycoComplex

  1. Mushrooms are hard to identify and keep fresh
    We would all like to benefit from the medicinal properties of mushrooms, but these days, it’s a risky practice: knowledge is no longer being handed down from one generation to the next and it’s easy to confuse an edible species with a poisonous one. In addition, many mushrooms decompose rapidly after being picked and produce mycotoxins which cause botulism. If they’re consumed after being stored in unsuitable conditions (they should be hermetically sealed and kept refrigerated below 4°C), it can result in serious food poisoning with no detectable changes in their appearance, taste or smell.
  2. Encapsulating them ensures maximum efficacy
    Mushrooms contain many health-beneficial compounds but they also have a high water content which dilutes these compounds. When dehydrated and encapsulated, the mushrooms are converted into dry matter which is exceptionally concentrated in active principles.
    Loose powder is more economical but once opened, it quickly oxidises which makes it less effective over time. In contrast, capsules offer stable active principles and are precisely dosed. They’re easy to use, practical and safe.
  3. One of the most promising areas of medicine
    Metabolically rich, mushrooms offer huge pharmacological potential, with considerable research being conducted in this field. The areas of medicine in which they’re used are growing all the time: antibiotic therapy, cardiology, haematology, oncology, parasitology …
  4. A formulation with guaranteed active principles
    Organic Mycocomplex is produced from the carpophores in mushrooms, the part with the highest therapeutic value. Many manufacturers use mycelium for their dietary supplements, but this underground part is composed of strands and is much lower in beneficial substances.
  5. Natural, organic excipients
    Organic Mycocomplex capsules are free from lactose, gluten, gelatine, soya, flavourings, pesticides, fungicides, artificial colours, allergens, GMO substances and animal products. The mushrooms used are grown in line with organic farming specifications. Their cellular compounds, including polysaccharides and triterpenes, are extracted using a unique enzymatic formula which initiates fermentation of chitin walls. Solvents are then added, primarily water, but also alcohol when appropriate.

Many experts agree that mushrooms currently represent one of the most promising areas of medicine, and that their huge potential is only just starting to be scientifically evaluated. With its exceptional range of benefits, Organic MycoComplex has more than earned its place in the SuperSmart catalogue.

Written: December 2018

Buy Organic MycoComplex to fight fatigue and boost the immune system.

CompositionOrganic MycoComplex
Daily dose: 3 capsules
Number of doses per pack: 30
Amount per dose
Combination of organic mushroom extracts standardised to 30% polysaccharides and 07% triterpenes.
Inonotus obliquus 200 mg
Trametes versicolor 200 mg
Cordyceps militaris 150 mg
Ganoderma lucidum 150 mg
Agaricus brasiliensis 100 mg
Lentinula edodes 100 mg
Grifola frondosa 100 mg
Extract of Radix panax ginseng C.A. Meyer Standardised to 20% de ginsenosides 50 mg
Fructo-oligosaccharides 50 mg
Sodium selenite providing 50 mcg of elemental selenium 109 mcg
Other ingredients: acacia gum.
Directions for useOrganic MycoComplex
adults. Take 3 capsules a day.
This product should not be taken alongside diabetes medication. Its use is contra-indicated in type 1 diabetics, those with coagulation disorders and those who have had a transplant.
Beehive with yellow flower, with two Japanese style wooden salt spoons filled with raw propolis and bee pollen

This supplement contains red propolis, a rare substance with an exceptionally rich nutritional content that’s harvested from the mangroves of Brazil. It has the highest level of antioxidant phenolic compounds of all the forms of propolis and is the most effective at supporting immune function.

Its extraordinary pharmacological potential (antibacterial, anti-inflammatory, antiviral, antioxidant) exceeds that of green propolis, which is itself a remarkable, highly-valued product (1). It contains more isoflavones which significantly improve menopause-related symptoms.

What benefits are offered by Red Propolis?

As confirmed by scientists some decades ago, the use of propolis dates back several thousand years. More recently, researchers have discovered that it has an astonishing number of additional biological and therapeutic properties useful in everyday life (2-4). We now know that propolis plays a part in:

  • Stimulating the immune system to prevent infection (5-6). The immune system can become less responsive when the temperature drops or when it’s subjected to a stream of external aggressors, making the body more vulnerable to viruses, bacteria and pathogenic fungi. Propolis contains micronutrients for preventing such a scenario: it helps ‘mobilise the troops’ (increasing the number of macrophages) and gets them fitter, faster (by stimulating their lytic activity) due to its role in hundreds of enzymatic processes.
  • Helping the immune system fight infection and bacterial attack (7). Not content with optimising the efficacy of immune cells, propolis also provides them with a variety of natural antibiotic compounds that combat the growth of pathogenic bacteria, inhibit the synthesis of their DNA and break down their cell walls. Individually, these molecules have a modest effect but when combined, they are formidable and help the body repel aggressors using exogenous compounds. They are, in a manner of speaking, additional ‘weapons and external troops’ that ‘swell the ranks’ of our immune cells. They include, for example, galangin, kaempferol and pinocembrin, all of which have a powerful anti-fungal effect, as well as caffeic acid esters which disrupt the progress of viruses from cell to cell.
  • Fighting inflammation (8-9). The flavonoids in red propolis interfere with the production of certain inflammatory mediators (especially prostaglandins and leukotrienes), in a similar way to aspirin (but via a unique mechanism).

These remarkable properties mean that red propolis can fight infection of all kinds (ENT problems, sore throats, rhinopharyngitis, sinusitis), reduce their duration, and increase the effects of conventional treatments against fungal problems and bacteria (10-11).

Other studies have shown that some of its components help stem DNA synthesis in abnormal cells, increase levels of glutathione (an endogenous antioxidant), curb lipid peroxidation, reduce oxidative stress, decrease the toxic effects on the liver caused by alcohol and certain drugs, and lessen menopause-related symptoms.

Why is red propolis so effective?

Several studies have demonstrated that red propolis is the most effective variety in terms of antioxidant potency (12). It contains more than 300 beneficial micronutrients (13):

  • Volatile terpenes (limonene, terpenes, oleic acid esters …) which are partly responsible for its analgesic and anti-inflammatory effects.
  • Phenols (flavonoids, lignans, tannins, coumarins …) some of which are specific to red propolis (elemicin, isoliquiritigenin, trans-anethole, methyleugenol, dalbergin, vestitol, medicarpin…) (14) and which offer marked antioxidant and cytoprotective effects (15-16).
  • Triterpenes (lupeol, amyrin) to which its antimicrobial effects are partly attributed (17).
  • Specific isoflavones which reduce symptoms of the menopause.
  • And inorganic precious elements such as copper, manganese, iron, calcium and vanadium.

Where does red propolis come from?

Propolis is a sealant used by bees for strengthening the hive interior, making it more air- and water-tight and better-able to resist microbial and fungal attack. The bees make it from anti-pathogenic resins (18-19) gathered from tree buds and bark, which they mix with wax and saliva. The propolis is then collected by beekeepers by scratching the ‘frames’ of the beehive, after which the wax and impurities are removed. The final product is a complex concentrate of phytonutrients from the tree buds and micronutrients from the bees.

In Europe, bees make propolis from poplar trees or conifers. In Brazil, however, where ecosystems are infinitely richer, there are around 13 types of propolis which vary depending on the plant source used by the bees. They include red propolis, recognised as the variety containing the most antioxidant phytonutrients and demonstrating the highest antioxidant activity(20). It gets its red colour from a unique flavonol pigment called retusapurpurine (21).

It is produced from a climbing tree with vine-like branches: Dalbergia ecastophyllum (22-24) which grows in the mangroves (swampy tropical forests) of northern Brazil. In this extraordinary environment, far from intensive farming, the bees collect a bright red, resinous exudate, which is associated with the presence of a local parasite.

Green propolis is produced by bees in southern Brazil from a completely different species called Baccharis dracunculifolia (25).

Five good reasons to take Red Propolis

Red Propolis is an exceptional, natural and very rare product (annual production in Brazil is estimated to be just 1-2 tons), the manufacture of which relies on high-quality French extraction facilities.

  1. It’s the most bio-rich, effective and rarest of all the varieties of propolis.
  2. It comes in capsule form and thus leaves no bitter taste in the mouth.
  3. The fact that it’s freeze-dried means all the properties of its ingredients are well-preserved with a long ‘shelf-life’. This is not the case with fresh, chewable propolis, the quality of which is often mediocre.
  4. It contains much higher levels of isoflavones than other types of propolis, which helps improve symptoms of the menopause.
  5. It’s the best natural product for supporting the immune system throughout the winter period and in stressful situations.

How should you take Red Propolis?

It’s a good idea to also take the following steps throughout your supplementation with red propolis capsules, for increased benefits:

  • Increase your intake of fruit and vegetables to ‘up’ your exogenous antioxidant levels. These external compounds will give your immune defences a boost and complement their activity.
  • Make sure you get enough sleep. There’s no doubt that lack of sleep impairs the quality of your immune response.
  • Pay attention to your diet. Poor diet is the main reason for a weak immune system: even mild deficiencies in key micronutrients (selenium, copper, vitamin E, vitamin A …) can play a significant role in the daily battle that takes place between the body and pathogens. Taking a good quality multivitamin supplement during periods of fragile health can help optimise immune processes.
  • Avoid synthetic cleaning products, cigarette smoke and pesticides. Exposure to these substances damages the immune system.

For synergistic effects, its possible to combine Red Propolis with other supplements available to buy at Supersmart, such as those of barberry extract, a powerful anti-bacterial which also helps lower blood sugar levels, zinc orotate, which has well-documented preventive effects against the common cold, vitamin C, invaluable in winter for boosting white cell numbers, and a medicinal mushroom complex enriched with ginseng and selenium.

Royal jelly, standardised in 10-HDA, is also a good option for boosting the immune defences, ideally at each change in season.

Note: Red propolis is not recommended for those with allergies to beehive products.

Buy Red Propolis capsules to support the immune system.

CompositionRed Propolis
Daily dose: 2 capsules
Number of doses per pack: 30
Amount per dose
Extract standardised to 20% red propolis and 7% flavonoids 800 mg
Other ingredients: maltodextrin, acacia gum, white rice bran.
Directions for useRed Propolis
adults. Take 2 capsules a day.
Each capsule contains 400 mg of extract standardised to 20% red propolis and 7% flavonoids.

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