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Blood sugar and cholesterol Advice

The 5 best anti-cholesterol supplements

Elevated cholesterol can put you at risk. Choose natural, safe solutions to reduce the impact of cholesterol on your body and maintain your health.
Artichokes piled up
Extract of artichoke stimulates the secretion of bile and which helps eliminate unused cholesterol.
Rédaction Supersmart.
2020-06-19Comments (0)

Remember – with cholesterol, it’s all about balance

If you want to take better care of your cardiovascular system, remember that when it comes to cholesterol, it’s important to differentiate between the ‘good’ and ‘bad’ forms. The key is to aim for the best possible balance between the two.

You should prioritise healthy dietary fats (primarily vegetable ones), and limit unhealthy ones (fresh and cooked meats, butter …). If you want to do more to maintain your health as effectively as possible, try these five natural solutions which can actively help you combat ‘bad’ cholesterol.

Artichoke for reviving a sluggish liver

Known for its distinctive flavour, artichoke is a popular ingredient in summertime dishes. Perhaps less well-known is its amazing ability to lower blood cholesterol levels! In fact, the common artichoke, or Cynara Scolymus, is rich in cynarin, a bitter polyphenol whose primary benefit is its ability to revive a sluggish liver.

How is this beneficial in reducing cholesterol ? Well, it’s in the liver that bile salts, the principal components of bile, are produced. Bile is one method the body uses to break down cholesterol. Artichoke also stimulates the secretion of bile, thereby activating the elimination of unused cholesterol and preventing it from being stored.

In addition, artichoke inhibits cholesterol production in the body, mainly as a result of its high levels of the flavonoid luteolin. This benefit was identified by researchers who observed reduced cholesterol levels among subjects treated with artichoke leaf extract (1).

In practice: the best way of getting maximum benefit from artichoke’s properties is to take a supplement containing artichoke extract such as Liver Support Formula).

Red yeast rice for reducing blood cholesterol

As its name indicates, red yeast rice is a type of fungi grown on rice. Though little-known in the West, it is widely-used in Asian cuisine. Red yeast rice is rich in monacolin K, a substance with similar effects to those of the most widely-prescribed anti-cholesterol treatments.

More specifically, it inhibits one of the enzymes responsible for an early step in cholesterol synthesis in the liver, and thus reduces the release of cholesterol into the bloodstream. Red yeast rice increases levels of HDL (‘good’ cholesterol) and lowers those of both LDL (’bad’ cholesterol) and triglycerides. (2)

In practice: red yeast rice should be taken in the evening as cholesterol is primarily synthesised in the liver at night. The supplement Red Yeast Rice Extract is ideal in this regard.

Attention: red yeast rice is very powerful and side-effects have been reported at high levels of intake. Be sure to seek advice from your pharmacist before taking it.

Psyllium, a ‘raincoat’ for the intestines

Psyllium is a small plant from the same family as the plantain, the pharmacological properties of which come from the mucilage of its seeds. Mucilage is a substance which captures water and swells to form a sticky gel.

It is this mucilage which enables excess cholesterol to be captured, preventing it from crossing the small intestine barrier. Mucilage also stimulates digestive movements and in this way, psyllium makes it easier to eliminate ‘bad’ cholesterol from the body. (3)

In practice: the recommended dose is 5 grams of psyllium powder (Psyllium Seed Husk) a day, diluted in water.

Attention: psyllium is also known to reduce blood sugar and care should therefore be taken by those with diabetes.

Phytosterols, natural mimics of cholesterol

Phytosterols, which include beta-sitosterol, sitostanol, and campesterol, are very similar to cholesterol apart from the fact they are of plant origin.

It’s important to note that cholesterol is absorbed in the gut after forming micelles – smaller molecules that are more easily transported into the bloodstream. Because of their close resemblance, phytosterols and cholesterol compete for incorporation into micelles, with the former able to displace the latter. As a result, cholesterol (deprived of its micelle ‘vehicle’) is eliminated by natural means.

Phytosterols also act at an earlier stage, preventing cholesterol from forming micelles in the first place. They thus fulfil a comprehensive action which is complemented by their own low rate of absorption: after fulfilling their anti-cholesterol role, they are eliminated naturally. It’s worth noting that phytosterols are even more effective when taken alongside a diet low in unhealthy fats. (4)

In practice: phytosterols are readily available in supplement form (for example Beta-Sitosterol).

Pantethine and its synergistic action

Pantethine is a molecule produced from vitamin B5 (pantothenic acid). Its long-recognised benefits for cholesterol levels are related to several mechanisms.

Pantethine helps improve the transport and absorption of good cholesterol, which leads to a better balance between the good and bad forms. Pantethine has also been shown to be effective at inhibiting cholesterol production.

It’s also a precursor of coenzyme A, a molecule that’s essential for burning fat in the body (including cholesterol) to produce energy. What’s more, there are no side-effects associated with pantethine and only a low dose is needed to produce health benefits. (5)

In practice: the recommended daily amount of pantethine is generally 600mg, to be taken in three doses (Pantethine).

A combination of excess bad cholesterol and insufficient good cholesterol can put you at significant cardiovascular risk. To lower that risk, it’s essential to eat a balanced diet and reduce your intake of unhealthy fats as much as possible. But plants can also provide considerable support, so it would be a shame to miss out on their cholesterol-lowering properties!


  1. de Falco, Bruna & Incerti, Guido & Amato, Mariana & Lanzotti, Virginia. (2015). Artichoke: botanical, agronomical, phytochemical, and pharmacological overview. Phytochemistry Reviews. 14. 10.1007/s11101-015-9428-y.
  2. Venero CV, Venero JV, Wortham DC, Thompson PD. Lipid-lowering efficacy of red yeast rice in a population intolerant to statins. Am J Cardiol. 2010 Mar 1;105(5):664-6.
  3. Anderson JW, Davidson MH, Blonde L, Brown WV, Howard WJ, Ginsberg H, Allgood LD, Weingand KW. Long-term cholesterol-lowering effects of psyllium as an adjunct to diet therapy in the treatment of hypercholesterolemia. Am J Clin Nutr. 2000 Jun;71(6):1433-8.
  4. Phytosterols: natural compounds with established and emerging health benefits Elke A. Trautwein, Isabelle Demonty OCL 14 (5) 259-266 (2007)
  5. Evans M, Rumberger JA, Azumano I, Napolitano JJ, Citrolo D, Kamiya T. Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation. Vasc Health Risk Manag. 2014;10:89–100. Published 2014 Feb 27. doi:10.2147/VHRM.S57116


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