- Form of vitamin B3 (niacinamide) involved in hundreds of enzymatic reactions.
- Helps maintain healthy skin.
- Helps reduce cholesterol levels in the liver.
- Supports normal function of the arteries and nervous system.
Niacinamide is a dietary supplement containing physiologically active vitamin B3. Once ingested, it is converted in the body into nicotinic acid which has the same type of vitamin activity. Niacinamide supplementation fits well in any complementary regime to hold back ageing and prevent visible skin damage.
Vitamin B3 is a molecule essential to health. In particular, it helps to:
Niacinamide (also known as nicotinamide, nicotinic acid amide, 3-pyridinecarboxamide) is the active form of vitamin B3, which is sometimes referred to as niacin or vitamin PP. In fact, niacin is converted in the body into niacinamide which is a major precursor of two co-enzymes vitally important for health: NAD (nicotinamide adenine dinucleotide) and NADPH (nicotinamide adenine dinucleotide phosphate). Put simply, these co-enzymes ensure the supply of energy to cells: they play a role in more than 200 vital enzymatic reactions.
Numerous studies have shown that levels of these two co-enzymes decrease with age (1-4) particularly in skin tissue, a decline that may be related to senescence. As we grow older, our skin cells secrete less collagen: niacinamide may help restore its production (5). It may also help to improve the appearance of ageing, sun-damaged skin.
Niacinamide is less effective than niacin at reducing blood cholesterol levels. Though both molecules have the same vitamin activity, this cholesterol-lowering benefit may not be vitamin-related.
Taking large amounts of niacin invariably causes skin flushes (especially on the face and neck) and itching within 60 minutes of ingestion. This does not happen with niacinamide and it thus constitutes an excellent alternative for those who need a significant amount of B3, to treat pellagra, for example.
Certain plant-source foods such as beans, wheat and oats contain a small amount of niacinamide as do animal organs like liver, kidneys and muscle (6-7).
Niacin, which as mentioned, is converted into niacinamide in the body, is more available in the diet, particularly from animal products:
Nowadays, deficiency in vitamin B3 is rare. It is only seen in severely undernourished people and alcoholics.
Taken long-term, large amounts of vitamin B3 can have negative effects, particularly on liver health. You are therefore strongly recommended to consult a health professional before taking it for extended periods.
You should also seek medical advice before starting supplementation if you are being treated for alcoholism, liver disease or hypercholesterolaemia, as niacinamide can interact with drug molecules associated with such treatments.
Vitamin B3 acts synergistically with other B vitamins (particularly B1, B2 and B6). In cases of deficiency, it’s therefore best to take a supplement that contains all 8 B vitamins.
In addition, as part of an anti-ageing programme, it’s a good idea to adopt the following measures throughout the supplementation period:
|Daily serving: 4 capsules
Number of servings per bottle: 45
|Quantity per serving|
|Niacinamide||2 000 mg|
|Other ingredients: Acacia gum, rice bran.|
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