A unique formulation, Hemo Comfort is a high-grade dietary supplement specifically formulated to help combat problem haemorrhoids, reducing their size and associated bleeding. Discover the different plants that make up this supplement and their multiple benefits.
Brief recap of haemorrhoids
Haemorroids (also known as ‘piles’) are a network of small blood vessels located around the anus.
Genetic predisposition, frequent constipation or a sedentary lifestyle can all cause these internal and external blood vessels to dilate. Excessive dilation can be a major source of discomfort: increased haemorrhoid volume, itching, bleeding during bowel movements, pain... When it gets to this stage, it is referred to as haemorrhoidal disease (1-3).
What exactly does the supplement Hemo Comfort contain?
The good news is that research has identified several natural, plant-source compounds that can help combat excessive haemorrhoid dilation. The supplement Hemo Comfort thus contains the following 4 bio-active substances which have been shown to be particularly effective:
- horse chestnut extract (standardised to 20% aescin). Horse chestnut is the most effective known natural venotonic. Its benefits come primarily from its aescin content, a mixture of saponins with anti-oedema effects. Horse chestnut is used for invigorating venous circulation, by sending blood back towards the heart, and for helping to lower blood pressure in the legs. Horse chestnut is thus widely used to help combat problem haemorrhoids and varicose veins. It may also help to maintain healthy skin (4-9);
- diosmin extracted from the fruit of Citrus aurantium, , also known as Seville or bitter orange. This flavone is often used in cases of acute or chronic haemorrhoids. Several studies have shown diosmin to be effective in relieving the pain and bleeding associated with the condition (10-13);
- hesperidin, also derived from the fruit of Citrus aurantium. Hesperidin is a citrus bioflavonoid which promotesincreased venous tone. It is believed to have vasculoprotective, venotonic and anti-hypertensive effects. These multiple properties make it a useful substance for helping to reduce haemorrhoid problems(14-16) ;
- troxerutin extracted from the flowers of Sophora japonica, also known as the Japanese pagoda tree. Part of the oxerutin family, this flavonol is used for helping to protect blood vessels and combat haemorrhoid problems. According to some studies, it also plays a role in fighting the generation of free radicals associated with a high-cholesterol diet (17-20).
What are the benefits offered by Hemo Comfort?
All the compounds in this supplement act synergistically to help combat problem haemorrhoids.
Firstly, the aescin in horse chestnut, and the hesperidin work together to help invigorate venous circulation, lower blood pressure and reduce excessive haemorrhoid dilation (and thus size) (21-23).
Hemo Comfort deliberately combines specially-selected venotonic flavonoids namely diosmin, hesperidin and troxerutin) which have proved highly effective at helping to reduce the oedema, thrombosis, bleeding and pain specific to this condition (24).
How should this natural anti-haemorrhoid supplement be taken?
To benefit from Hemo Comfort’s excellent properties, take 4 vegetarian capsules a day with a glass of water.
Daily dose: 4 capsules
Number of doses per pack: 30 |
Amount per dose |
Diosmin (from 950 mg of extract of Citrus aurantium fruit, standardised to 95% diosmin) |
900 mg |
Hesperidin (from 1000 mg of extract of Citrus aurantium fruit, standardised to 90% hesperidin) |
900 mg |
Horse chestnut extract standardised to 20% aescin |
700 mg |
Troxerutin (from 305 mg of extract of Sophora japonica flowers, standardised to 99% troxerutin) |
300 mg |
Other ingredients: acacia gum, white rice flour. |
Adults. Take 4 capsules a day.
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- Sun Z, Migaly J. Review of Hemorrhoid Disease: Presentation and Management. Clin Colon Rectal Surg. 2016;29(1):22-29. doi:10.1055/s-0035-1568144
- Ekici U, Kartal A, Ferhatoglu MF. Association Between Hemorrhoids and Lower Extremity Chronic Venous Insufficiency. Cureus. 2019;11(4):e4502. Published 2019 Apr 19. doi:10.7759/cureus.4502
- Gallelli L. Escin: a review of its anti-edematous, anti-inflammatory, and venotonic properties. Drug Des Devel Ther. 2019;13:3425-3437. Published 2019 Sep 27. doi:10.2147/DDDT.S207720
- Bylka W, Kornobis J. Ruszczyk kolczasty, w leczeniu chorób naczyń zylnych [Butcher's Broom, in the treatment of venous insufficiency]. Pol Merkur Lekarski. 2005;19(110):234-236.
- Margină D, Olaru OT, Ilie M, et al. Assessment of the potential health benefits of certain total extracts from Vitis vinifera, Aesculus hyppocastanum and Curcuma longa. Exp Ther Med. 2015;10(5):1681-1688. doi:10.3892/etm.2015.2724
- MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001;6(2):126-140.
- Wilkinson JA, Brown AM. Horse Chestnut - Aesculus Hippocastanum: Potential Applications in Cosmetic Skin-care Products. Int J Cosmet Sci. 1999;21(6):437-447. doi:10.1046/j.1467-2494.1999.234192.x
- Underland V, Sæterdal I, Nilsen ES. Cochrane summary of findings: horse chestnut seed extract for chronic venous insufficiency. Glob Adv Health Med. 2012;1(1):122-123. doi:10.7453/gahmj.2012.1.1.018
- Giannini I, Amato A, Basso L, et al. Flavonoids mixture (diosmin, troxerutin, hesperidin) in the treatment of acute hemorrhoidal disease: a prospective, randomized, triple-blind, controlled trial [published correction appears in Tech Coloproctol. 2015 Oct;19(10):665-6]. Tech Coloproctol. 2015;19(6):339-345. doi:10.1007/s10151-015-1302-9
- Lohsiriwat V. Hemorrhoids: from basic pathophysiology to clinical management. World J Gastroenterol. 2012;18(17):2009-2017. doi:10.3748/wjg.v18.i17.2009
- Diana G, Catanzaro M, Ferrara A, Ferrari P. Attività della diosmina pura nel trattamento della malattia emorroidaria [Activity of purified diosmin in the treatment of hemorrhoids]. Clin Ter. 2000;151(5):341-344.
- Tajana A, Boccasanta P, Micheletto G, Orio A. Risultati dell'uso della diosmina (venosmine) per applicazione topica nel trattamento della patologia acuta emorroidaria [Results of the use of topical diosmin (venosmine) in the treatment of acute hemorrhoid pathology]. Minerva Med. 1988;79(5):387-390.
- Giannini I, Amato A, Basso L, et al. Flavonoids mixture (diosmin, troxerutin, hesperidin) in the treatment of acute hemorrhoidal disease: a prospective, randomized, triple-blind, controlled trial [published correction appears in Tech Coloproctol. 2015 Oct;19(10):665-6]. Tech Coloproctol. 2015;19(6):339-345. doi:10.1007/s10151-015-1302-9
- Lohsiriwat V. Hemorrhoids: from basic pathophysiology to clinical management. World J Gastroenterol. 2012;18(17):2009-2017. doi:10.3748/wjg.v18.i17.2009
- Homayouni F, Haidari F, Hedayati M, Zakerkish M, Ahmadi K. Blood pressure lowering and anti-inflammatory effects of hesperidin in type 2 diabetes; a randomized double-blind controlled clinical trial. Phytother Res. 2018;32(6):1073-1079. doi:10.1002/ptr.6046
- Giannini I, Amato A, Basso L, et al. Flavonoids mixture (diosmin, troxerutin, hesperidin) in the treatment of acute hemorrhoidal disease: a prospective, randomized, triple-blind, controlled trial [published correction appears in Tech Coloproctol. 2015 Oct;19(10):665-6]. Tech Coloproctol. 2015;19(6):339-345. doi:10.1007/s10151-015-1302-9
- Squadrito F, Altavilla D, Oliaro Bosso S. Double-blind, randomized clinical trial of troxerutin-carbazochrome in patients with hemorrhoids. Eur Rev Med Pharmacol Sci. 2000;4(1-2):21-24.
- Riccioni, C.; Sarcinella, R.; Izzo, A.; Palermo, G.; Liguori, M. (2004). "Effectiveness of Troxerutin in association with Pycnogenol in the pharmacological treatment of venous insufficiency". Minerva cardioangiologica 52 (1): 43–48. PMID 14765037 [archive]
- Lu, J.; Wu, D. -M.; Zheng, Z. -H.; Zheng, Y. -L.; Hu, B.; Zhang, Z. -F. (2011). "Troxerutin protects against high cholesterol-induced cognitive deficits in mice". Brain 134 (3): 783–797. doi:10.1093/brain/awq376. PMID 21252113 [archive]
- Gallelli L. Escin: a review of its anti-edematous, anti-inflammatory, and venotonic properties. Drug Des Devel Ther. 2019;13:3425-3437. Published 2019 Sep 27. doi:10.2147/DDDT.S207720
- Lohsiriwat V. Hemorrhoids: from basic pathophysiology to clinical management. World J Gastroenterol. 2012;18(17):2009-2017. doi:10.3748/wjg.v18.i17.2009
- Squadrito F, Altavilla D, Oliaro Bosso S. Double-blind, randomized clinical trial of troxerutin-carbazochrome in patients with hemorrhoids. Eur Rev Med Pharmacol Sci. 2000;4(1-2):21-24.
- Giannini I, Amato A, Basso L, et al. Flavonoids mixture (diosmin, troxerutin, hesperidin) in the treatment of acute hemorrhoidal disease: a prospective, randomized, triple-blind, controlled trial [published correction appears in Tech Coloproctol. 2015 Oct;19(10):665-6]. Tech Coloproctol. 2015;19(6):339-345. doi:10.1007/s10151-015-1302-9