CLA 800 mg is a unique dietary supplement containing patented conjugated linoleic acid (CLA), naturally obtained from safflower oil. Conjugated linoleic acid is a derivative of linoleic acid, an essential fatty acid which is part of the omega-6 family.
It was discovered completely by chance in the 1980s by scientists investigating carcinogens in grilled meat. Following a number of animal studies, the properties of this fatty acid were used in veterinary medicine to improve the muscle/fat ratio in livestock and its use has since been extended.
CLA is found in several animal-source foods, as bacteria in the digestive systems of ruminants converts linoleic acid into CLA. The mammary glands of these animals also appear to be able to perform this conversion (2).
The Western diet (non-vegetarian) typically provides just 0.5-1g of CLA a day (4). The foods that contain CLA are generally very high in calories, so recommending an increased intake of these foods to anyone watching their weight is not an option.
What about converting linoleic acid into CLA? Humans do not appear to be able to convert plant-source linoleic acid into conjugated linoleic acid as can ruminants, even if this only occurs in minute amounts under the effect of bacterial flora (3) and via a mechanism that remains poorly understood.
It has been developed from safflower oil, which is naturally rich in essential polyunsaturated fatty acids (65%-80 % stearic acid).
Around 70% of the CLA found in food is ‘trans-10, cis-12’ and 30% ‘cis-9, trans-11’ while in the supplement CLA 800mg, these two compounds are present in equal amounts. It therefore delivers 4.8g of the two main active isomers.
The CLA isomers accumulate in human tissue (particularly the liver, mammary tissue, adipose tissue and serum) and are metabolised via several metabolic pathways.
In the morning, after exercise, or with a meal: any time of day is fine. The recommended dose is 3g a day.
CLA 800 mg has been tested in 18 different clinical trials and no side-effects have been reported at recommended doses. A two-year clinical study showed no evidence of serious side-effects from long-term supplementation with conjugated linoleic acid.
No research has so far been conducted on combining CLA 800mg with specific diets. However, for cutting calories and initiating weight loss, the normal advice is to eat a balanced diet with the emphasis on fruits, vegetables and wholegrains.
| Daily serving: 6 capsules Number of servings per bottle: 20 |
Quantity per serving |
| Conjugated linoleic acid (from 6 g of safflower oil, standardized to 80% conjugated linoleic acid) | 4 800 mg |
| Other ingredients: Glycerol, water, a combination of tocopherol.
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