Liposomal glutathione supplement, endogenous antioxidant

Liposomal Glutathione is a liquid liposomal glutathione supplement providing 900mg per measuring cap, the highest dose on the market.

Offered in its reduced from (the biologically active form), it acts synergistically with the antioxidant vitamin C to protect cells against oxidative stress. It benefits from innovative technology based on liposomal encapsulation which protects it from gastric juices, thus increasing its absorption in the gut.

This supplement forms part of our Anti-ageing category.

Definition of glutathione

Glutathione is a protein, more specifically, a tripeptide, which is produced by the body from three amino acids: glutamic acid, cysteine and glycine (1).

Dubbed ‘king of the antioxidants’ by scientists, it is our most powerful endogenous (produced by the body) protective compound.

Ubiquitous in living organisms, it occurs naturally in plants, fungi and animal cells.

What role does glutathione play?

Glutathione is involved in maintaining redox potential in cell cytoplasm. While its oxidised form has a pro-oxidant effect, its reduced form (GSH or L-glutathione) constitutes a first line defence for cells(2).

Though produced by virtually all the body’s cells including those of the nervous system, it is in the liver where the largest reserve of glutathione is found (3). This invaluable substance thus has remarkable liver-related detoxification properties, and is responsible for eliminating many ‘xenobiotic’ (foreign) toxins. Amongst others, it processes metabolites from tobacco, alcohol and therapeutic drugs.

In addition, its thiol grouping binds with heavy metal salts (mercury, lead, cadmium...) enabling them to be safely excreted by the body (4).

Glutathione is also a precursor of many detoxifying enzymes, including glutathione peroxidase responsible for neutralising waste products from cellular respiration or the process of ‘cell death’ (apoptosis) (5).

Glutathione is used intravenously in conventional medicine for haemodialysis patients at risk of anaemia, for metabolic problems (diabetes) and age-related neurodegenerative disorders.

It is also worth noting that glutathione levels decline with age, starting from around the age of 50. Low glutathione levels are often observed in patients with various neurological, visual and cardiovascular disorders (6-7).

What are the benefits of liposomal glutathione?

Taken orally, glutathione has inherently low bioavailability as it faces two key obstacles: the strong acidity of gastric juices and the action of a liver enzyme called gamma-glutamyltranspeptidase (GGT) which catalyses the first stage of its breakdown (8).

Liposomal glutathione is more effective than other forms as it benefits from innovative encapsulation technology. Here, the glutathione is contained within a casing made from phospholipids, liposomes, which protect it from digestive secretions and ensure it completes its journey to the intestinal barrier in its reduced form (9).

By way of example, scientists studying rats with rheumatoid arthritis demonstrated the superiority of liposomal glutathione over standard glutathione by measuring biomarkers of oxidative stress and inflammation. They observed a greater reduction in levels of rheumatoid factor, malondialdehyde and C-reactive protein (10).

3 raisons why Liposomal Glutathione is the best of its kind

SuperSmart’s Liposomal Glutathione stands out from other liposomal glutathione supplements in that it offers:

1. an an exceptional dose of 900mg of glutathione per 10ml measuring cap, putting it among the most highly-dosed supplements on the market;
2. a recognised synergy with vitamin C(700mg per dose), a well-known antioxidant which helps to maintain reduced glutathione concentrations at a cellular level. Studies have also identified low glutathione levels in individuals with inadequate vitamin C intakes (11) ;
3. a convenient liquid form, with a pleasant exotic-fruit flavour, which you simply dilute in a drink.