- Helps with uncomplicated respiratory infections (colds, sinusitis, bronchitis and pharyngitis).
- Acts as an immune system booster, a powerful anti-viral and an anti-bacterial agent.
- Improves inflammatory response by naturally activating PPAR-gamma.
ParActin® is an extract of Andrographis in vegetarian capsules, standardised to more than 50% andrographolid, 14-deoxyandrographolid and neoandrographolid.
It is the most concentrated and scientifically supported extract on the market, now available to buy at Supersmart. This plant, native to India and Sri Lanka, is considered the herb for combatting winter ailments (colds, ‘flu, pharyngitis, sore throat), though recent studies suggest its therapeutic properties go far beyond such applications.
Andrographis paniculata, from the Acanthaceae family, grows on the plains of Southern Asia, particularly in Indonesia, India, China and Thailand. Closely related to Echinacea, this annual plant is indeed more commonly known as «Indian Echinacea». It has been used for hundreds of years in traditional Asian systems of medicine such as Chinese and Ayurvedic, to treat fever and respiratory infections.
Its efficacy in this respect has been confirmed by clinical trials. Indeed, the World Health Organisation has recognised its effectiveness in preventing and treating uncomplicated respiratory infections (colds, sinusitis, bronchitis and pharyngitis). It reduces both the symptoms and duration of these seasonal ailments.
Preliminary research has shown that ParActin® improves inflammatory response by naturally activating PPAR-gamma, thus inhibiting NF-kappa B activity (a key regulator of inflammatory response mechanisms), which reduces the production of the pro-inflammatory proteins and cytokines associated with pain and redness (especially IL-2, COX2, TNF, interferon-gamma and PGE-2).
Even though inflammation is the body's first response to an attack, scientists now recognise it as a key element of most major diseases: asthma, Alzheimer's, multiple sclerosis, inflammatory bowel disease and rheumatoid arthritis. ParActin® may therefore have applications in these various diseases.
With regard to bone health, in vitro studies have also shown that ParActin® both inhibited NFAT activity, a transcription factor associated with bone erosion, and stimulated bone mineralisation via expression of Cox-2, offering potential benefits in the prevention of osteoporosis.
In mouse studies, ParActin® produced a clear improvement in learning and memory and thus seems able to reduce cognitive decline associated with spatial performance. In two-month-old mice, administration of ParActin® over four weeks even increased the development of new neurons. In preventing hyperphosphorylation of tau proteins, it also reduces long-term depression (LTD) by inhibiting the glycogen synthase kinase-3β and thus counteracts neuronal cell deterioration.
These studies also demonstrated its ability to reduce hyperphosphorylation of tau proteins which stabilise microtubules and are abundant in the brain. When tau proteins become defective and are no longer able to perform this role properly, the result can be dementias such as Alzheimer's disease.
For optimal efficacy, the recommended daily dose is 3 x 100mg capsules of ParActin® spread over the day.
Buy ParActin® for anti-inflammatory protection.
|Daily dose : 3 capsules
Number of doses per pack: 30
|Amount per dose|
|ParActin® (Andrographis paniculata leaf extract standardised to 50% andrographolide, 14-deoxyandrographolide and neoandrographolide)||300 mg|
|Other ingredients: Acacia gum, rice flour.|
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