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NAD+ Cellular Activator is an anti-ageing face cream with a revolutionary composition that is extremely effective at reducing wrinkles, firming the skin and giving you a radiant complexion.
Its innovative formula, the direct result of the latest research into NAD+, combines the most powerful active ingredients in the field of skin rejuvenation.
This premium facial treatment is therefore included in our category of products dedicated to the skin.
Composition and proven benefits of our anti-ageing face cream
What does this moisturising and firming facial care product contain?
NAD+ Cellular Activator combines 6 key active ingredients:
- RejuveNAD™: this young sunflower shoot extract stimulates the skin's natural vitality mechanisms by increasing levels of NAD+, a cofactor essential for energy production in cells, and therefore for their performance, regeneration and longevity. RejuveNAD™ exerts this action by improving the expression of the NAMPT enzyme (+111%) (1). A randomised, placebo-controlled clinical study on 22 women aged 52 to 65 found an improvement in skin smoothness, a lifting effect and a visible reduction in signs of ageing, including wrinkles and crow's feet, after 42 days' application of a cream containing 2% RejuveNAD™, the same concentration used in our product (2);
- niacinamide: this active form of vitamin B3 is a precursor of NAD+, the well-known molecule just mentioned, which is essential for the production of cellular energy and therefore for skin youthfulness. In this cream, niacinamide helps to improve the skin's elasticity and radiance, reduce visible pores and discolouration and strengthen the skin's resilience in the face of daily stress (3);
- Alpine Rose Active: the Alpine rose is a plant that grows at high altitude in acidic, nutrient-poor soil, and has developed impressive strategies to protect itself from free radical attack. Its leaf extract has been studied for its ability to eliminate senescent fibroblasts (the main cells in connective tissue) without affecting healthy cells, by inhibiting the carbonylation of skin proteins induced by reactive oxygen species (4-5). A placebo-controlled study of 44 women aged between 40 and 65 who applied a cream based on 2% of the ingredient (the same concentration used in our product) for 14 days showed its ability to make skin more elastic and reduce skin redness (6);
- Ameliox™: this liposomal preparation combines carnosine, an antioxidant peptide, with two powerful fat-soluble antioxidants, silymarin and tocopherol. Ameliox™ helps maintain skin elasticity and firmness by preventing glycation, a slow natural process that affects the structure and activity of dermal proteins (collagen and elastin), leading to premature ageing. An in vivo study of 20 women aged between 38 and 65 showed an improvement in skin softness, firmness and hydration, as well as a reduction in the depth of wrinkles on the forehead and crow's feet, after 28 days of topical application of a cream containing 2% of the ingredient, the same concentration as that used in our product (7);
- resveratrol: this polyphenol is recognised for its powerful antioxidant properties and its ability to activate sirtuins and support mitochondria, the cell's energy centres. In this anti-wrinkle cream, it helps to support the skin's youthfulness and firmness, giving it a more even, luminous complexion (8);
- low molecular weight hyaluronic acid: hyaluronic acid is an essential component of connective tissue, responsible for retaining water to ensure the skin's hydration, suppleness and volume. Thanks to its smaller molecular size, the hyaluronic acid in this product penetrates deeper into the epidermis to provide long-lasting hydration, plump your skin and reduce the appearance of fine lines and wrinkles (9).
The formula is completed by functional agents which guarantee its stability, texture and good tolerance, while optimizing hydration and skin comfort.
We have chosen not to include fragrance in the cream, which is the main source of allergens in cosmetic products on the market.
Anti-wrinkle cream results and clinical evidence
A number of studies carried out on our facial care product have quantified its invaluable benefits:
- record satisfaction and efficacy: in a dermatologically controlled use test with clinical scoring (carried out on 21 people with wrinkles, aged between 48 and 68, who applied NAD+ Cellular Activator to their face twice a day for 28 days), 95% of the panel said they liked the product. 95% of those tested also felt that it softened and moisturised their skin well. For 90%, it made their skin firmer, and for 81%, it helped to reduce facial sagging and had a noticeable rejuvenating effect. What's more, 100% of the subjects surveyed agreed that the cream did not leave their skin greasy, was easy to spread and absorbed quickly;
- a visible reduction in wrinkles: at the end of the same test, clinical evaluations carried out by a dermatologist showed a statistically significant reduction in forehead wrinkles (-15%) and crow's feet (-13%);
- proven moisturising power: the formula provides a long-lasting moisturising effect that is still +56% after 8 hours, according to a test carried out on 10 women with dry to very dry skin, aged between 51 and 70, using corneometer measurements. More than 6 out of 10 subjects even considered this cream to be the most effective they had ever tested;
- exemplary skin tolerance: a compatibility test confirmed the ‘very good skin tolerance’ of this facial care product.
4 key benefits of our anti-wrinkle facial treatment
NAD+ Cellular Activator has 4 strong points:
- an innovative formula based on science and SuperSmart's expertise in longevity: this anti-ageing treatment is based on the latest advances concerning NAD+, SuperSmart's unique expertise and ingredients renowned for their effects on firmness, hydration and radiance;
- renowned, effective and synergistic active ingredients: the formula combines rare and powerful ingredients, such as RejuveNAD™, Alpine Rose Active and Ameliox™, with complementary properties;
- clinically proven results: dermatological tests reveal remarkable effectiveness in reducing wrinkles and improving skin comfort and appearance;
- a healthy, velvety composition: vegan, fragrance-free and 98% natural origin, this anti-wrinkle product offers a light, silky texture that is quickly absorbed, without leaving a sticky residue. It has a Yuka score of 86/100.
What is in NAD+ Cellular Activator
Any questions?
Our team of nutrition experts and scientists has the answers.
To really work on wrinkles, you need to combine a healthy lifestyle with effective skin care:
- get enough regular sleep, which encourages cell regeneration
- keep well hydrated, because drinking enough water helps keep skin supple
- protect your skin from UV rays, which are responsible for the majority of premature wrinkles, by adjusting your protection according to the intensity of the sun
- stop smoking and limit alcohol consumption, two factors that accelerate skin ageing
- learn how to manage stress, because chronic elevation of cortisol alters collagen
- exercise regularly to improve blood circulation and oxygenation of the tissues
- apply a topical moisturising and antioxidant cream (rich in niacinamide, hyaluronic acid, resveratrol, etc.: such as NAD+ Cellular Activator) to boost skin firmness;
- act from the inside out by choosing a balanced diet rich in antioxidants (fruit, vegetables, quality proteins, etc.) and ideally food supplements rich in essential nutrients (omega-3, collagen, vitamin C, zinc, etc.) to support skin regeneration and protection
Hyaluronic acid is generally recognised as the most plumping anti-ageing active ingredient.
It draws water into the skin, increasing its volume and suppleness, for a rapidly visible effect.
It is one of the key substances in NAD+ Cellular Activator.
Research shows that the most effective skincare products for slowing and fading the signs of skin ageing act on firmness, hydration and cellular vitality.
Active ingredients such as niacinamide (a precursor of NAD+), hyaluronic acid and resveratrol are widely recognised for improving skin texture and radiance.
These ingredients are combined in NAD+ Cellular Activator.
As well as using this anti-ageing cream, we recommend that you work from the inside out by buying food supplements for the skin: collagen, the structural protein of connective tissue (see our Marine Collagen), and borage and evening primrose oils with their moisturising and repairing properties (Borage & Evening Primrose).
There are also synergistic formulas, notably rich in hyaluronic acid and biotin (such as Daily Beauty or Natural Skin Formula).
We also suggest you buy supplements based on longevity research: a mix of NAD+ 'boosters' (with NAD+ Booster Formula), a complex of ingredients studied as part of the fight against senescent or 'zombie' cells (see Senolytic Complex) or a formula designed to combat glycation, the process that stiffens collagen fibres and accelerates skin ageing (e.g. Anti-Glycation Formula).
february 13 2026
Une superbe découverte. Cette crème NAD+ est parfaite pour les peaux mixtes. Elle pénètre instantanément, possède une texture non collante et une odeur fraîche très agréable. On sent que la technologie cellulaire agit tout en respectant l'équilibre de la peau. Un excellent produit que je rachèterai sans hésiter
A superb discovery. This NAD+ cream is perfect for combination skin. It penetrates instantly, has a non-sticky texture, and a very pleasant fresh scent. You can feel the cellular technology working while respecting the skin's balance. An excellent product that I will repurchase without hesitation.
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february 11 2026
J’utilise la crème visage anti-âge NAD+ Cellular Activator de SuperSmart depuis quelques semaines et je suis vraiment agréablement surprise. La texture est légère, fondante et pénètre rapidement sans laisser de film gras, et vraiment c'est un gros + au quotidien ! Ma peau est plus lisse, plus hydratée et visiblement plus lumineuse. J’apprécie particulièrement sa formule riche en actifs comme le RejuveNAD, la niacinamide, le resvératrol et l’acide hyaluronique. Mention spéciale pour la composition : 98 % d’origine naturelle, sans parfum et testée dermatologiquement. Une très belle découverte pour une peau plus ferme et radieuse
I have been using the NAD+ Cellular Activator anti-aging face cream from SuperSmart for a few weeks and I am really pleasantly surprised. The texture is light, melting, and absorbs quickly without leaving a greasy film, and really it's a big plus on a daily basis!
My skin is smoother, more hydrated, and visibly more radiant. I particularly appreciate its formula rich in active ingredients like RejuveNAD, niacinamide, resveratrol, and hyaluronic acid.
Special mention for the composition: 98% of natural origin, fragrance-free, and dermatologically tested. A very nice discovery for firmer and more radiant skin.
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february 11 2026
É la prima volta che utilizzo questo prodotto, lascia la pelle morbida, idratata e più luminosa. Unica piccola pecca, la profumazione... sicuramente migliorabile!
This is the first time I use this product, it leaves the skin soft, hydrated, and more radiant. The only small flaw is the fragrance... definitely improvable!
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february 10 2026
La crème Nad + cellular activator et très agréable à porter, elle est légère, pas grasse, ma peau ne tiraille pas du tout, ma peau est souple.
The Nad + cellular activator cream is very pleasant to wear, it is light, not greasy, my skin does not feel tight at all, my skin is supple.
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february 6 2026
J AI 84 ANS J 'utilise cette crème depuis un mois environ et j'ai un pot d'avance car il faut voir les résultats au bout de 3 mois environ, en attendant je peux dire que j'aime sa texture et qu'elle me laisse la peu très douce, je suis satisfaite
I am 84 years old. I have been using this cream for about a month and I have an extra jar because you need to see the results after about 3 months. In the meantime, I can say that I like its texture and it leaves my skin very soft. I am satisfied.
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