Resveratrol Synergy is an anti-ageing supplement formulated from an optimal combination of several antioxidants which work synergistically in the body to exert a protective effect. Antioxidants defend the body from certain types of cell damage, thus slowing down cellular ageing. Their effects help prevent the development of certain diseases and complications which may be seriously damaging to health.
What are the ingredients in Resveratrol Synergy?
The antioxidant composition of our anti-ageing formulation is truly comprehensive. The antioxidant effects of its components help combat the oxidative stress and free radical damage responsible for cellular ageing. Offering optimal protection, our product has been specially formulated to include around 10 of the most powerful antioxidants, including resveratrol. Found in grape skin, this is a natural polyphenol recognised for its antioxidant potency. For maximum efficacy, our product contains the bioactive form called trans resveratrol. This anti-ageing supplement also combines, in a single capsule, other compounds such as:
- Pterostilbene, a highly bioavailable compound from the same family as resveratrol, with anti-inflammatory, anti-neoplastic and antioxidant properties.
- Polydatin, a resveratrol glucoside, ie, a molecule of resveratrol bound to one of glucose.
- Quercetin, a potent antioxidant with significant anti-inflammatory power, the action and bioavailability of which are boosted in the presence of vitamin C.
- Proanthocyanidins, extracted from pine bark, with antioxidant and anti-inflammatory properties.
- Fisetin, extracted from Buxus sinica, recently added for its stabilising effect on resveratrol.
With this combination of nutrients to modulate longevity gene expression, Resveratrol Synergy mimics the effects of calorie restriction, improves biomarkers of ageing and boosts disease-fighting mechanisms. Calorie restriction is the most scientifically-validated way of extending lifespan in all living organisms – it can increase lifespan by almost 100% in certain species. It works by favourably altering gene expression, one of the body’s adaptive responses to reduced calorie intake. By activating certain genes and inhibiting others, calorie restriction significantly slows down the ageing process by promoting healthy cell function.
Senolytic Complex is a completely new ‘senolytic’ formulation for fighting the ageing process, based on the very latest discoveries in anti-ageing medicine, now available to buy at Supersmart. The term ‘senolytic’, recently coined by the scientific community, describes the ability to eliminate senescent cells (ie, aged cells), the presence of which has been identified in recent years as being, along with oxidative stress and telomere shortening, one of the causes of ageing. Since there was previously no way of preventing or slowing down this process, Senolytic Complex constitutes a truly revolutionary treatment.
The formulation contains the most powerful, natural, senolytic compounds identified to date: quercetin (in a form 20 times more bioavailable than standard quercetin), theaflavin, and most importantly, fisetin, an extraordinary flavonoid that’s really setting the scientific community alight.
Who is Senolytic Complex aimed at?
Senolytic Complex is for anyone over 40, whether as a course of treatment, or as long-term supplementation, to eliminate senescent cells and prevent their reappearance.
It is particularly recommended for the following groups of people:
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Those who wish to extend their life expectancy.
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Those keen to maintain good physical condition and optimal health as they age.
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Those who are already suffering from age-related problems (muscle weakness, cardiovascular disorders, vision and hearing impairment, cognitive decline, osteoporosis …) and those who wish to reduce their risk of developing them.
How does Senolytic Complex work?
The discovery of senescent cells invading the body
In 2014, researchers achieved a major advance in the fight against ageing. They identified old, worn-out cells in the tissues of subjects aged over 40. Termed ‘senescent’, these zombie-like cells (1) are deformed and unable to divide, and are distributed throughout the body’s tissues. Though no longer functioning normally, they are not eliminated and thus accumulate pathologically.
These cells are rare in young people but increase with age, particularly in adipose tissue, skeletal muscle, blood vessels, the brain, kidneys and skin (2-3).
Their dramatic effects on healthy cells and on the body
Unfortunately, senescent cells do not just take over, they also impede the activity of neighbouring healthy cells by continually releasing pro-inflammatory cytokines (IL-1, IL-6 and IL-8), vesicles and insoluble proteins (fibronectin, collagen) into the extracellular environment (4-7). These substances are really distress calls: they signal to other cells the advanced state of deterioration in which they find themselves, but at the same time, they significantly affect the function of neighbouring healthy cells (8)!
Over the last three years, a number of studies have shown that the level of senescent cells in the body is directly linked to the pace of ageing (9) and the development of age-related health problems. Even a small amount of these cells is enough to wreak havoc in tissues(10) and induce the onset of many age-related problems: systemic inflammation, arthritis, atherosclerosis, chronic diseases (11), sarcopenia, cataracts, insulin resistance, vascular hypo-reactivity (12) (13) ...
How can we get rid of these ‘parasitic’ cells?
These cells normally destroy themselves in a process called apoptosis, in order to avoid damaging the body. However, this mechanism does not always work in which case the senescent cells continue to parasitize the body and cause chaos all around them (14).
Fortunately, researchers have identified several compounds that are specifically capable of repairing this defective mechanism and bringing about the self-destruction of these senescent cells. These extraordinary compounds are called ‘senolytics’.
The first study to identify senolytics was published in 2015 in the well-known scientific journal Aging Cell (15). Quercetin, a natural flavonol compound, combined with an anti-cancer drug, was found to dramatically decrease both the number of senescent cells and secretion of pro-inflammatory factors in the organism studied. In just five weeks, this combination resulted in a significant reduction in mortality and physical deterioration.
Dozens of studies have since identified natural compounds with the same properties (16-17). This has led to the development of a revolutionary new therapy, senolytic treatment, which is able to selectively destroy senescent cells and thus reduce the severity of age-related diseases, increase resilience and longevity, and delay the effects of ageing.
The treatment is essentially a massive ‘spring clean’, after which healthy cells regain control of the body and again function at full capacity. It represents a significant advance in the fight against ageing.
The very latest research shows that a formulation such as this can produce powerful rejuvenating effects, improve the condition of those affected by age-related health problems, slow down the ageing process and extend lifespan. Exceptional benefits which place this dietary supplement right at the top of anti-ageing nutrition and which should come as welcome news for many people…