Clear Skin Formula food supplement combines 7 natural active ingredients to help eliminate acne and other skin imperfections (redness, inflammation...), while supporting the health and harmony of the skin.
In particular, it contains burdock extract and lactoferrin, which have been extensively studied for their ability to regulate sebum, soothe inflammation and prevent skin disorders.
This product is therefore classified in our skin category.
Composition and benefits of this dietary supplement against acne and skin blemishes
What exactly is acne?
Acne is an inflammatory skin condition caused by a number of mechanisms:
-
overproduction of sebum: sebum is an oily substance naturally secreted by the sebaceous glands to protect and moisturise the skin. Hormonal changes can increase the production of androgens (such as testosterone and DHT), which stimulate these glands, leading to an excess of sebum, causing the first acne lesions;
-
clogged pores: excess sebum combines with dead skin cells to form the characteristic comedones (blackheads and whiteheads) that block the hair follicles;
-
bacterial proliferation: in this clogged environment, the Cutibacterium acnes bacterium develops, triggering a local inflammatory reaction that can lead to the appearance of papules, pustules and even more pronounced nodules.
This process is also accompanied by increased oxidative stress, which delays the healing of lesions and encourages their reappearance.
Benefits of the 7 ingredients in our oral formula for clear skin
Our synergistic oral formula is specially designed to help you maintain or regain healthy, blemish-free skin, including reducing acne symptoms.
It contains 7 top ingredients:
-
burdock root extract (Arctium lappa) 4:1: this biennial herbaceous plant from the Asteraceae family is traditionally used in phytotherapy to purify the skin. Burdock helps to maintain healthy skin by regulating the activity of the sebaceous glands, thereby reducing excessive sebum secretion. Rich in polyphenols, it is also said to have soothing properties in the face of skin inflammation. It also has the advantage of supporting detoxification pathways and therefore reducing the accumulation of toxins, which can be beneficial for acne-prone skin. A human observational study found that administration of burdock reduced acne lesions, improved the GAGS score (a standardised clinical scale assessing the severity of acne) and improved patients' quality of life (1);
-
lactoferrin: this glycoprotein of the transferrin family is naturally present, in reduced quantities, in milk and biological fluids. Lactoferrin is widely studied for its potential ability to reduce skin eruptions by limiting excessive sebum production, the proliferation of Cutibacterium acnes bacteria and inflammation, thereby contributing to clearer, calmer skin. For example, a randomised, double-blind, placebo-controlled clinical trial involving 168 participants suggests that lactoferrin supplementation significantly reduces acne lesions, particularly inflammatory flare-ups (2);
-
milk thistle seed extract (Silybum marianum) standardised for silymarin: milk thistle is a Mediterranean plant which also belongs to the Asteraceae family. Its seeds contain an active complex called silymarin, which supports liver health and the body's natural purification functions. This standardised extract promotes the elimination of toxins, reduces oxidative stress and helps limit excess hormones and inflammatory by-products, factors often involved in the appearance and persistence of acne (3);
-
N-acetylcysteine (NAC): this stable cysteine derivative is reputed to be a precursor of glutathione, the most powerful endogenous antioxidant, which helps neutralise the oxidative stress linked to acne inflammation. NAC is also being studied for its potential support in detoxifying the liver, thereby reducing the accumulation of toxins likely to cause skin eruptions (4);
-
vitamin A (retinyl acetate): this fat-soluble vitamin helps to maintain normal skin by supporting skin cell renewal and preserving the integrity of the epidermal barrier. It is present here in the form of retinyl acetate, a stable ester of retinol. A precursor of active retinoids, retinyl acetate is thought to play a key role in regulating keratinisation, helping to prevent clogged pores and the formation of blackheads, for smoother, more even skin (5);
-
vitamin B3 (nicotinamide): this water-soluble B-group vitamin is involved in skin health in a number of ways. Vitamin B3 helps to maintain normal skin by strengthening the epidermal barrier, supporting hydration, regulating sebaceous activity and reducing irritation and imperfections linked to inflammation. Several clinical studies have evaluated its effectiveness in reducing acne lesions. Here, we have selected nicotinamide, a well-tolerated, non-irritating form of vitamin B3, which acts without causing the redness associated with niacin (6);
-
vitamin B6 (pyridoxal 5'-phosphate): this water-soluble vitamin plays a key role in many metabolic processes, particularly hormonal and enzymatic. Vitamin B6 helps to regulate the hormonal activity (supporting the balance of androgens and thus helping to normalise sebum) involved in hormonal acne outbreaks, for example those linked to the menstrual cycle. Vitamin B6 is present here in the form of pyridoxal 5'-phosphate (P-5-P), its biologically active form directly assimilated by the body (7).
5 key benefits of this natural supplement for healthy, pure skin
Clear Skin Formula has 5 key strengths:
-
a complete, exclusive synergy targeting acne and skin imbalances: this unique formula combines 7 major active ingredients which act in synergy on the various causes of acne and other skin imperfections;
-
ingredients with proven efficacy: lactoferrin, NAC and silymarin have been the subject of extensive scientific research into sebum regulation, liver detoxification and inflammation reduction;
-
beauty action from within: the formula works at the heart of the skin's mechanisms to restore balance and support clear, soothed and radiant skin;
-
highly bio-available forms of vitamins: vitamins A, B3 and B6 are offered in active forms (retinyl acetate, nicotinamide and pyridoxal 5'-phosphate) for optimal absorption and effectiveness;
-
100% vegetable capsules, with no excipients: with this product, you can also enjoy vegetable capsules made entirely from hypromellose (HPMC), a compound derived from cellulose, with no additives or excipients.
Daily dose: 3 capsules
Number of doses per box: 30
|
Daily dose
|
N-acetylcysteine (NAC)
|
600 mg
|
Burdock root extract (Arctium lappa) 4:1
|
250 mg
|
Milk thistle seed extract (Silybum marianum)
Of which silymarin
|
125 mg
100 mg
|
Lactoferrin (milk)
|
100 mg
|
Vitamin B3 (nicotinamide)
|
48 mg
|
Vitamin B6 (pyridoxal 5'-phosphate)
|
10 mg
|
Vitamin A (retinyl acetate)
|
1000 mcg
|
Other ingredient: hypromellose capsule.
|
Recommended amount: take 3 capsules a day with meals.
Duration: 30 days.
Storage: keep away from light, heat and moisture.
Watch out: consult a health professional before use if you have any health problems. Not recommended for pregnant or breastfeeding women, or in cases of known allergy to the Asteraceae family.
Precautions: adults only. Do not exceed the recommended daily dose. This product is a dietary supplement and should not be used as a substitute for a varied, balanced diet or a healthy lifestyle.
- Miglani A, Manchanda RK. Observational study of Arctium lappa in the treatment of acne vulgaris. Homeopathy. 2014 Jul;103(3):203-7. doi: 10.1016/j.homp.2013.12.002. PMID: 24931753.
- Chan H, Chan G, Santos J, Dee K, Co JK. A randomized, double-blind, placebo-controlled trial to determine the efficacy and safety of lactoferrin with vitamin E and zinc as an oral therapy for mild to moderate acne vulgaris. Int J Dermatol. 2017 Jun;56(6):686-690. doi: 10.1111/ijd.13607. Epub 2017 Mar 30. PMID: 28369875.
- Sharifi R, Pasalar P, Kamalinejad M, Dehpour AR, Tavangar SM, Paknejad M, Mehrabani Natanzi M, Nourbakhsh M, Ahmadi Ashtiani HR, Akbari M, Rastegar H. The effect of silymarin (Silybum marianum) on human skin fibroblasts in an in vitro wound healing model. Pharm Biol. 2013 Mar;51(3):298-303. doi: 10.3109/13880209.2012.721789. Epub 2012 Nov 8. PMID: 23137300.
- Mardani N, Mozafarpoor S, Goodarzi A, Nikkhah F. A systematic review of N-acetylcysteine for treatment of acne vulgaris and acne-related associations and consequences: Focus on clinical studies. Dermatol Ther. 2021 May;34(3):e14915. doi: 10.1111/dth.14915. Epub 2021 Mar 18. PMID: 33629414.
- Cook M, Perche P, Feldman S. Oral Vitamin A for Acne Management: A Possible Substitute for Isotretinoin. J Drugs Dermatol. 2022 Jun 1;21(6):683-686. doi: 10.36849/JDD.6781. PMID: 35674761.
- Walocko FM, Eber AE, Keri JE, Al-Harbi MA, Nouri K. The role of nicotinamide in acne treatment. Dermatol Ther. 2017 Sep;30(5). doi: 10.1111/dth.12481. Epub 2017 Feb 21. PMID: 28220628.
- Coburn SP, Slominski A, Mahuren JD, Wortsman J, Hessle L, Millan JL. Cutaneous metabolism of vitamin B-6. J Invest Dermatol. 2003 Feb;120(2):292-300. doi: 10.1046/j.1523-1747.2003.12034.x. PMID: 12542535.