- Produced naturally from olive trees (Olea Europaea).
- Exceptional content in oleuropein (125mg standardised to 32%).
- Clinically-proven effects.
- Helps lower levels of LDL-cholesterol and triglycerides.
- Combats lipid peroxidation in blood vessels.
Olive Leaf Extract is a natural formula in vegetarian capsules produced from olive leaves, designed to control lipidemia. It is supported by three clinical studies which have confirmed its ability to lower LDL-cholesterol and triglyceride levels, increase HDL-cholesterol and fight lipid peroxidation, now available to buy at Supersmart.
Olive Leaf Extract a natural-source dietary supplement produced from olive leaves. It contains a very high level of oleuropein, a bioactive phytonutrient specific to the olive tree, which helps control blood lipids and prevent carbohydrate absorption.
It is aimed at anyone who wants to improve their cardiovascular health and maintain the integrity of their blood vessels. Individuals with the following risk factors are likely to be particularly interested in this product:
The beneficial effects of the olive tree are attributed to its exceptionally high content in phenolic compounds, molecules known for their antioxidant potency. In the olive tree, these compounds play a part in defending the tree from insects, infection, multiple microbial attacks and UV radiation (1-2), but they are also biologically active when ingested by humans. They are known to reduce the risk of a number of diseases by combatting free radicals and improving enzymatic balance.
Oleuropein is the most abundant phenolic compound in the olive tree (3) (accounting for around 25% of the extract). It is oleuropein that gives extra virgin olive oil its characteristic bitterness, but there are many other such compounds found in Olive Leaf Extract: apigenin, caffeic acid, catechins, coumaric acid, diosmetin, ferulic acid, gallic acid, hesperidin, hydroxytyrosol, luteolin, oleoside, quercetin, rutin, tyrosol, vanillin, verbascoside…
As the oleuropein in olive leaves has been scientifically shown to be responsible for the plant’s benefits, Olive Leaf Extract is formulated to contain an optimum amount of this compound.
Olive Leaf Extract’s effects on the cardiovascular system.
Olive leaves have been used in phytotherapy since antiquity apparently for their antilipidemic, antiseptic and antiviral properties.
Scientific research has since confirmed these applications and identified new properties: antimicrobial (4-5), antiviral (6), antifungal (7), gastro-protective (8), blood glucose-lowering (9), blood pressure-lowering (10), antioxidant (11-12), antiatherogenic (13), hypolipidemic (14), anti-inflammatory (15), neuro-protective (16), vasodilatory (17) and anti-ageing (18).
There are three precise mechanisms of action which are responsible for the majority of Olive Leaf Extract’s effects on the cardiovascular system:
1) Cholesterol-lowering action
The olive tree’s polyphenols, particularly oleuropein, act on cholesterol excretion (19). They promote the elimination of excess cholesterol via the bile ducts, duodenum and finally faeces.
2) Antioxidant action
The antioxidant potential of oleuropein is exceptional. When elderly institutionalised individuals followed a diet enriched with an extract of oleuropein and its derivatives for six weeks, their antioxidant capacity was shown to improve (20). It is a natural solution to combatting oxidative stress and inhibiting LDL oxidation (21).
3) Action on sugar absorption
By binding to sucrase and maltase, two digestive enzymes, oleuropein limits sugar absorption and thus reduces spikes in blood glucose. It also does this by slowing down the activity of the sugar transporter, GLUT2.
The effect of Olive Leaf Extract capsules has been directly measured in three clinical trials (22).
1) One year’s supplementation with 250mg a day
Following 12 months’ daily supplementation by subjects with elevated cholesterol levels, researchers recorded:
2) Four weeks’ supplementation with 250mg a day
In overweight subjects, there was a significant improvement over four weeks in the expected ratio of coronary risk as compared with placebo. A clear decrease in triglycerides was observed.
3) Eight weeks’ supplementation with 250mg a day
The third study examined the ability of Olive Leaf Extract to reduce oxidative stress. Results showed that daily supplementation with 250mg reduced levels of MDA (malondialdehyde) by almost a third, a urinary marker of oxidative stress.
Studies suggest that the leaves and fruit are equally rich in oleuropein (23), but the olive leaf is considered a more renewable natural source for extraction (24). Hence its use in Olive Leaf Extract, and its ingredient Olécol®.
1) The antioxidant content of olives depends to a large extent on variety, maturity and preservation. Therefore, if you live a long way away from the Mediterranean region where they’re grown, you can’t really rely on eating olives all year round to boost your cardiovascular health. With its exceptional and stable content in olive tree polyphenols, Olive Leaf Extract provides a solution to this problem, offering populations the world over the opportunity to fully benefit from the advantages of a Mediterranean diet.
2) Eating a Mediterranean diet is associated with a lower risk of all-cause mortality (25). Scientific studies have in large part attributed these protective effects to the role played by the olive tree (26).
3) The bioavailability of oleuropein in humans is very high – between 55% and 60% (27). Maximal plasma concentration occurs two hours after oral administration. Studies have also shown that oleuropein crosses the blood-brain barrier easily.
4) The Mediterranean diet was recognized by UNESCO in 2010 as an Intangible Cultural Heritage of Humanity.
5) Cardiovascular disease is the leading cause of mortality across the world, claiming more than 17 million lives each year.
To further enhance the efficacy of Olive Leaf Extract, you can adopt these additional measures throughout the supplementation period:
These measures are part of the Mediterranean diet which is based on the long-term food habits of Mediterranean populations. They are a good accompaniment to supplementing with Olive Leaf Extract though not essential for obtaining the benefits of this product.
Note: this product should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. It’s important to follow the guidelines on how to take it and the recommended dose, and to use it by the ‘best before’ date. It is not recommended for women who are pregnant or breastfeeding, or for children under 15. Keep out of children’s reach. Store in a cool, dry place.
Buy Olive Leaf Extract to help lower cholesterol and blood sugar.
|Dose: 2 capsules
Number of doses per pack: 30
|Amount per dose|
|Olecol®, extract of Olea Europaea leaf standardised to 32% oleuropein||250 mg|
|Other ingredients: acacia gum, rice bran.
Olecol®, Bioactor, Netherlands.
Xanthohumol is a hop flower supplement containing an exceptional antioxidant flavonoid called xanthohumol. It’s a phenolic compound that’s 200 times more powerful than the resveratrol in red wine, and offers truly exceptional, cell-boosting properties. Beer is the only dietary source of xanthohumol though the levels it contains are very low.
Wine-lovers appreciate the drink’s subtlety and sophistication but they also know it’s an exceptionally rich source of antioxidants. Indeed one such antioxidant is the most widely-studied anti-ageing substance ever: resveratrol. However, new research shows that beer is more than a match for its great rival. Beer is the only dietary source of xanthohumol, a natural cytoprotective antioxidant that’s 200 times more powerful than the resveratrol in red wine!
It was Hildegarde de Bingen, a 12th-century Benedictine nun and pharmacologist, who was responsible for introducing hops into beer. Before that, monks had used mainly coriander, gentian or sage to flavour and preserve their precious nectar, which was given to pilgrims in monasteries and abbeys. It was immediately evident that the hop offered many benefits: with its preservative properties and positive effects, it quickly became an essential ingredient in the recipe. Over the centuries that followed, it would go on to be used by generations of brewers, right up to the present day. Though the monks had no way of knowing it, its meteoric rise was due to the hop’s high content in phenolic compounds – particularly xanthohumol. The problem is that these compounds, which come from the hop flower, are very delicate and tend to make the beer a bit cloudy. The majority of modern, large-scale beer producers therefore use a chemical (pVPP) to eliminate this cloudiness and prevent deposits from forming in the bottle. So in order to obtain the benefits of xanthohumol, you need to drink artisanal beers with a strong hop content if possible (IPA, for example).
But the best way of benefiting from this cytoprotective compound (which we’ll undoubtedly be hearing more about in the future) is to take a hop flower supplement, standardised in xanthohumol, every day. It’s an ultra-modern solution (extracting the xanthohumol from the hop inflorescences is a major technological achievement) which draws on its ancient tradition of use and which avoids the oxidative effects of alcohol.
Hop flower extract standardised in xanthohumol offers four main benefits, all of which are backed up by the scientific literature:
Other studies have demonstrated its ability to regulate fat metabolism (by improving lipid parameters) and to boost the body’s defences and vitality. By no means exhaustive, this list identifies xanthohumol as a substance of major interest in terms of protection and actively contributing to factors affecting recovery.
Xanthohumol is extracted from the female cones of the hop plant, a climbing perennial which is added to beer to improve its taste, aroma, bitterness, frothy texture and preservation (14). It’s a chalcone-type antioxidant flavonoid, the only one of its kind, which is found solely in hop flowers. It’s therefore present in beer but in tiny amounts: due to the high temperatures used in the brewing process, it gets converted into another less powerful compound called isoxanthohumol. Some very hoppy beers (such as IPA) (15) contain more, as hops are added after brewing.
The hop has been regarded as a medicinal plant for centuries (16-17). Its use dates back to the monasteries of 8th century Europe(18), when it was used for its pharmacological properties, in particular for treating anxiety and sleep problems, for its benefits for the endocrine system and for its anti-tumour effects.
Xanthohumol’s mechanisms of action come from its extraordinarily high content of phenolic compounds. Recent studies show that regular consumption of these compounds can, in the long term, reduce the risk of many chronic health disorders such as cardiovascular disease (19). Phenols, and in particular, xanthohumol, exert modulatory effects in cells by interacting with a wide range of molecular targets of signalling pathways (mitogen-activated protein kinase, protein kinase C, detoxifying antioxidant enzymes …) (20). These effects translate into increased expression of certain cytoprotective genes, regulation of the normal cell cycle, inhibition of growth, an increase in apoptosis, inhibition of angiogenesis, as well as suppression of oxidative stress, a state of imbalance which impairs the structural and functional integrity of cell membranes (21). The role played by oxidative stress in the development of chronic diseases is now widely documented in the scientific literature (22). Phenolic compounds can also influence the composition of gut microbiota and re-establish intestinal barrier function, thus modulating the chronic inflammation associated with metabolic diseases (23).
Following ingestion, phenolic compounds such as xanthohumol are absorbed, distributed to various tissues and then metabolised by the liver. A proportion undergo partial conversion by gut flora. (24).
The recommended dose is two capsules a day, to be taken with meals.
If you want to boost its effects on sleep, it’s worth knowing that hops acts synergistically with other supplements available to buy at Supersmart such as valerian (found in the natural formulation Advanced Sleep Formula). For improving hormone balance, it’s better to combine it with an extract of pumpkin seeds.
Buy Xanthohumol capsules to support cellular health.
|Daily dose: 3 capsules
Number of doses per pack: 30
Amount per dose
|Extract of hop flower standardised to 10% xanthohumol||150 mg|
|Other ingredients: acacia gum, white rice flour.|
A senescent cell is one whose life cycle has come to a permanent end. In the normal scheme of things, such cells are eliminated from the body by the immune system. But in some cases, this fails to happen and they accumulate in tissues, with potentially serious consequences for health.