- Supports hepatic synthesis of glutathione, an essential antioxidant.
- Has anti-depressant properties.
- Eases joint pain, promotes mobility and protects cartilage from damage.
S-adenosyl-methionine (SAM-e) is a naturally-occurring compound in the body which promotes methylation, the process whereby methyl groups (one atom of carbon and 3 of hydrogen) are transferred from one molecule to another. Methylation is essential for many enzymatic processes and SAM-e is the most active of all methyl donors. Indeed, SAM-e has been the subject of dozens of clinical studies involving thousands of patients.
SAM-e plays a crucial role in conjunctive tissue synthesis; it eases joint pain, promotes mobility and protects cartilage from damage. In 2002, an American government agency, the Agency for Healthcare Research and Quality (AHRQ) concluded that SAM-e was 80% more effective than a placebo at relieving osteo-arthritis pain, and as effective as non-steroidal anti-inflammatories (NSAIDs) at treating osteo-arthritis. NSAIDs are associated with serious side-effects while SAM-e has health benefits for the whole body:
We introduced SAM-e into Europe in 1998 and while its price has now been reduced by over 70%, it remains an expensive nutrient. It should be recognized that:
Like SAM-e, other substances with excellent therapeutic potential are also available as nutritional supplements. Super Quercetin, for example, is a quercetin concentrate with antioxidant, anti-inflammatory, anti-carcinogenic and cardio-protective properties. Two natural extracts also recognised for their therapeutic efficacy are French oak, for reducing fatigue and improving mood, and St John's Wort Extract, for combatting mild to moderate depression.
Alternative spelling/keywords : SAM e, SAMe, SAM_e, SAM
|Daily serving: 2 tablets
Number of servings per bottle: 30
|Quantity per serving|
|Elemental S-Adenosyl Methionine (obtained from 1 600 mg of S-Adenosyl L-Methionine-disulfate p-toluenesulfonate)||800 mg|
|Other ingredients: Microcrystalline cellulose, magnesium hydroxide, stearic acid, anhydrous calcium chloride, magnesium stearate, colloidal anhydrous silicon, calcium oxide, talc, shellac, arginine base, glycerol, silicon dioxide, sodium alginate.|