Complete your selection
5-HTP supplement is a natural extract of Griffonia Simplicifolia that acts as a serotonin percursor, often highlighted for its anti-fatigue properties and recommended as an effective, natural anti-depressant, now available to buy at Supersmart.
What is 5-HTP?
The molecule 5-HTP, or 5-Hydroxytryptophan, is found in its natural state in the seeds of Griffonia Simplicifolia, a climbing plant indigenous to Central and West Africa.
5-HTP is a derivative of the amino acid tryptophan. Once absorbed by the body, 5-HTP crosses the blood-brain barrier and is converted in the brain into serotonin, an inhibitory neurotransmitter involved in many biological processes. Serotonin plays a role in controlling circadian rhythms or bio-rhythms and is thus central to the regulation of sleep, anxiety, appetite and mood.
How does 5-HTP supplement influence serotonin?
Given its role in regulating the body’s biorhythms, maintaining serotonin at sufficient levels is clearly essential. It can be produced in various ways including through the conversion of 5-HTP. 5-HTP is the direct precursor of serotonin, produced naturally by the body from tryptophan.
Tryptophan is an essential amino acid which means it cannot be produced by the body and has be obtained from external sources, either from certain foods or from dietary supplements such as our product L-Tryptophan. Ingested tryptophan is then first converted into 5-HTP and then into serotonin, by the action of vitamin B6. Research has enabled this serotonin conversion process to be simplified by extracting 5-HTP from certain plants and formulating it into dietary supplements. As an immediate serotonin precursor, 5-HTP benefits thus include facilitating serotonin production in the brain.
What are the benefits associated with 5-HTP?
5-HTP’s role as a serotonin precursor has made it the subject of numerous studies.
- As mentioned, 5-HTP effects include increasing serotonin production in the brain and regulating a number of processes in the body.
- Its serotonin-boosting function is particularly useful since a lack of this neurotransmitter can manifest in a number of symptoms such as depression, sleep problems, migraine, food cravings, hunger, substance addiction, aggressiveness, anxiety, and obsessive behaviour.
- Because of these multiple symptoms, studies have been conducted on the therapeutic properties of 5-HTP, particularly for combatting stress and for treating depression and low mood.
- Some scientists believe it has anti-depressant effects similar to those of drugs such as PROZAC® and it is indeed often indicated for treating depression and low mood.
Our product has been specially formulated to offer the properties and benefits of 5-HTP. Each capsule contains 50 mg, making the recommended 5-HTP dosage two capsules a day. For optimal efficacy, they should be taken on an empty stomach, ideally two hours after a meal.
Because of this compound’s effects, certain precautions are necessary. This supplement should not be taken at the same time as anti-depressant drugs and it is important not to exceed 200mg of 5-HTP in 24 hours without medical supervision. If in any doubt, seek guidance from your therapist.
Buy 5-HTP capsules to support serotonin production.
What is in 5-HTP
Any questions?
Our team of nutrition experts and scientists has the answers.
As well as supplementing with 5-HTP, you may find these other nutritional supplements of interest too.
Discover the properties of Peptidea®, a fish protein hydrolysate that plays a regulatory role in the nervous system. See also L-Tryptophan, an essential amino acid and precursor of serotonin, melatonin and niacin.
This product’s capsules are composed of HPMC (hydroxypropyl methylcellulose), a plant substance derived from cellulose. HPMC is widely used for medicines and dietary supplements. It contains no animal ingredients, is recognised as safe by health authorities and is considered more sustainable than synthetic alternatives.
february 12 2026
favorise l'endormissement et améliore la qualité du sommeil grâce à sa composition bien étudiée dans ce sens.
promotes falling asleep and improves sleep quality thanks to its well-studied composition in this regard.
see the translation
Translated by SuperSmart - see the original
january 30 2026
Je n'ai vu aucun changement,
I have seen no change.
see the translation
Translated by SuperSmart - see the original
january 29 2026
Used for a while, works great.
january 25 2026
Ich nehme sie in der Früh um entspannt in den Tag zu starten . Am Nachmittag oder Abend eine zweite wenn nötig . Sie helfen super und man kann jederzeit die Einnahme beenden.
I take them in the morning to start the day relaxed. In the afternoon or evening a second one if necessary. They help a lot and you can stop taking them at any time.
see the translation
Translated by SuperSmart - see the original
january 25 2026
Ich nehme sie in der Früh um entspannt in den Tag zu starten . Am Nachmittag oder Abend eine zweite wenn nötig . Sie helfen super und man kann jederzeit die Einnahme beenden.
I take them in the morning to start the day relaxed. In the afternoon or evening a second one if necessary. They help a lot and you can stop taking them at any time.
see the translation
Translated by SuperSmart - see the original
Need help?
You may also like
of experience
your money back
##montant## purchase
Bonjour Carla,
Merci pour votre retour sur notre produit 5-HTP. Nous sommes ravis de savoir que vous le trouvez très bon. Cependant, nous avons remarqué que vous avez attribué une seule étoile à votre évaluation. Pourriez-vous nous préciser ce qui a motivé cette note afin que nous puissions mieux comprendre votre expérience et améliorer nos services ?
Votre retour est précieux pour nous et nous aide à nous améliorer continuellement.
Merci d'avance pour votre réponse.
Cordialement,
Gaëlle - L'équipe Supersmart