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Zinc L-carnosine (ZnC or polaprezinc) is a natural, effective and well-tolerated dietary supplement, which provides 17mg of zinc and 58mg of elemental carnosine. It is a chelated compound containing zinc, a mineral that helps fight intestinal inflammation, and L-carnosine, known to optimise zinc’s efficacy (1). It’s a natural solution that helps to protect the integrity of the gastric mucosa and reduce the symptoms associated with acid reflux.
What is in the supplement Zinc L-Carnosine?
ZnC contains, first and foremost, zinc, a mineral essential for good health, and one involved in more than 200 enzymatic reactions. It’s found in most types of meat and nuts, as well as in oysters, sesame seeds and pulses. The problem is, the body only absorbs 15%-40% of the zinc present in these foods, and absorption declines with age.
It also contains carnosine (β-Alanyl-l-histidine), arguably one of the most promising discoveries of recent years. It’s a peptide formed naturally by the body when protein-rich foods are digested. Carnosine improves the absorption of zinc as a result of its solubility and ability to gradually release zinc to the site of inflammation (1).
What are the benefits for gastric health?
Research has demonstrated the ability of ZnC to restore the gastric mucosa (2), and some studies even suggest this effect could extend to the whole of the digestive tract, from taste disorders to intestinal disturbances (6-8).
This is consistent with zinc’s ability, widely documented in the scientific literature, to support normal epithelial tissue function (9).
Acid reflux and stomach pain are often treated too lightly, but over time, they can generate serious consequences for health including ulcers, peptic stenosis (narrowing of the oesophagus).
What is in Zinc L-Carnosine
Any questions?
Our team of nutrition experts and scientists has the answers.
Protecting the stomach membrane and reducing the discomfort of acid reflux often requires the use of pharmaceutical substances, which are not without side-effects, ranging from simple antacids (chewable carbonate or calcium bicarbonate tablets) to proton pump inhibitors (PPIs) which directly tackle acid production by the stomach. Doctors also prescribe H2 antihistamines which, by blocking certain receptors in the stomach, reduce acid secretion and thus reflux. But these common remedies can all cause adverse side-effects, especially that of accelerating the risk of osteoporosis-related fractures.
Consuming plants such as liquorice, marshmallow or elm sometimes helps, with liquorice root extracts normally the most effective.
We recommend taking one vegetarian capsule in the morning and one in the evening, with meals.
As stomach problems can be exacerbated by various factors, we also recommend adopting the following steps throughout the supplementation period:
- try to reduce your alcohol consumption;
- don't smoke;
- maintain a healthy weight;
- avoid spicy food.
You could also try some other related supplements:
- Magnesium Malate, a magnesium supplement which helps prevent oesophagus muscles from contracting abnormally.
- Lactobacillus gasseri, a lactic bacteria supplement with recognised properties.
Finally, the long-term effects of supplementation with zinc L-carnosine are now well established: no side-effects have been reported in pre-clinical and clinal trials (10-11).
Gastroesophageal reflux, or acid reflux, is what happens when some of the stomach’s contents, particularly highly-acidic gastric juices, travel back up into the oesophagus. This produces what is known as heartburn (but which is actually oesophagus burn). Repeated acid reflux of this kind can have serious consequences: chronic inflammation can affect the oesophagus wall, which is not equipped to cope with such acidity, leading to serious damage (particularly ulcers).
This product’s capsules are made of pullulan, a natural polysaccharide obtained by fermenting tapioca or corn. Pullulan contains no animal ingredients and provides an excellent barrier to oxygen, helping to preserve the integrity of the capsule’s ingredients. It is also an eco-friendly alternative to synthetic materials.
may 10 2026
Whether it works remains to be seen
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may 6 2026
Trial over 3 months after already one month see the result
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april 19 2026
Super effective for my stomach
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april 6 2026
I noticed that when I take zinc I have much less eczema on my hands!
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march 26 2026
I have been taking zinc L-carnosine for about two months now, and I am really impressed by its effectiveness. From the very first days, I felt a clear reduction in intestinal pain. My stomach, which was extremely sensitive, is now much more soothed.
I have suffered from IBS for a long time and this supplement is clearly one of those that have brought me real improvement. I am continuing the treatment and I am gradually noticing even more digestive comfort.
I really recommend it for people with sensitive or irritated intestines.
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