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S-Acetyl Glutathione Supplement
S-Acetyl Glutathione Supplement
0640S-Acetyl Glutathione Supplement Size
S-Acetyl Glutathione 100 mg
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54.00 €(64.77 US$) is available
S-Acetyl Glutathione is the most absorbable and active form of glutathione
  • Promotes a balanced immune reaction.
  • Has antioxidant power, which helps to maintain mitochondrial integrity.
  • Helps to eliminate heavy metals, being an effective alternative to intravenous chelation.
90 Veg. Caps.
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S-Acetyl Glutathione Supplement - Antioxidant Glutathione for Immune Health

S-acetyl glutathione (SAG) is a new and superior alternative to reduced glutathione, with a better absorption in the body and several antioxidant benefits.

What is Glutathione?

Reduced glutathione, commonly known as glutathione or GSH, is a tripeptide made up of L-glutamine, L-cysteine and glycine. It is ubiquitous in all living systems. However, chronic oxidative stress reduces levels of cellular glutathione and its biosynthesis is affected by dietary and/or individual biological factors - a person's particular ability to metabolise its various precursors.

Glutathione is rightly considered the most important intracellular antioxidant produced by the human body. Until now, however, it has been necessary to take it either orally at high doses, or sublingually, in order to guarantee maximum absorption. Indeed, the major part of an oral dose of glutathione becomes oxidised before it can be absorbed and used by cells.

What are the benefits associated with S-acetyl Glutathione capsules?

In this form, glutathione's fundamental properties are thus preserved and increased, to:

  • Play a role in boosting mitochondrial energy production and function. Mitochondria, the energy-producing powerhouses of cells, are also the primary intracellular site of oxygen consumption and source of reactive oxygen species (ROS). SAG has been shown to cross the membrane of the mitochondria, increasing the organelle's activity and minimizing the generation of ROS, thus helping to maintain mitochondrial integrity and overall health.
  • Ensure protection against damage to DNA;
  • Eliminate heavy metals (mercury, lead, cadmium…) as well as organic toxins, while maintaining blood levels of magnesium. SAG is a simpler and equally effective alternative to intravenous chelation, which until now was considered the most active way of administering glutathione.
  • Protect against certain chronic diseases (herpes, HIV, Lyme disease, fibromyalgia, chronic candidiasis);
  • Reduce levels of TNF-alpha (an inflammatory marker), NF-kB and F-2 isoprostanes (oxidative stress markers);
  • There is growing evidence that intracellular glutathione levels in antigen-presenting cells (macrophages, for example) may influence Th1/Th2 cytokine response and promote a balanced immune reaction.
  • In addition, due to its selective effect on cancer cells, SAG is emerging as a promising new substance for lymphoma patients, since it increases cell apoptosis.

Why opt for S-acetyl glutathione?

Various studies have confirmed that this form it is better absorbed through the intestinal wall, as its acetyl bond prevents oxidation and helps the molecule to pass diffusively into the cell after absorption in the intestine. It is this acetylation that prevents the breakdown of glutathione. SAG, therefore, enters the cells directly and once inside, it is converted into reduced glutathione by cytoplasmatic thioesterases (sulphur atoms), which removes the acetyl group. This increases both total glutathione and the percentage of reduced glutathione, which has a very positive effect on oxidative stress biomarkers. Indeed, SAG is an active antioxidant in all tissues and in supporting immune function.

To boost the effect of SAG and restore glutathione levels, a precursor of this antioxidant is also available to buy from the SuperSmart catalogue: N-acetyl-cysteine (NAC), a particular form of L-cysteine. Like methionine, this amino acid contains a sulphur atom and plays a role in glutathione production. Other amino acids, such as Lysine and Branched-amino acids (leucine, isoleucine and valine), may also be of interest for the synthesis of active molecules. SAG also complements our other two forms of glutathione, Perlingual Gluthatione and Reduced Glutathione. It is now the most advanced and effective way of increasing levels of this essential endogenous antioxidant.

Buy S-acetyl Glutathione capsules to benefit from its anti-ageing properties.

Daily dose : 3 capsules
Number of doses per pack : 30
Amount per dose
S-acetyl-glutathione 300 mg
Other ingredients : Acacia gum, white rice bran.
Directions for use
Adults. Take 3 capsules a day.
Each capsule contains 100 mg S-acetyl-glutathione.
4.5 /5 4 reviews
4.7 / 5
4.3 / 5
Value for money
3.7 / 5

Reviews 4
50 %

long term use is good for stabilize the body, I will recommend a healthy diet to support the Glutathione
je n,ai plus de douleur intestinal .je n,ai jamais de rhume ni gripe.mes taches marrons qui apparaissaient ,vers l,age de 45 ans,on disparu et ma peau reste claire a 72 ans..produit tres serieux... je trouve le produit un peu cher surtout pour les toute petites retraites malgre les reductions tres interressante merci pour tout
bon produit pour l usage que j en fais
Lionne 83
  1. Grune, T., T. Reinheckel, M. Joshi and K. J. Davies (1995). "Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome." J Biol Chem 270(5): 2344-51
  2. Hensley, K., N. Hall, R. Subramaniam, P. Cole, M. Harris, M. Aksenov, M. Aksenova, S. P. Gabbita, J. F. Wu, J. M. Carney and et al. (1995). "Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation." J Neurochem 65(5): 2146-56.
  3. Schulz et al, Glutathione, oxidative stress and neurodegeneration, Eur J Biochem 267 (16):4904-11, 2000

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S-Acetyl Glutathione 100 mg
54.00 €
(64.77 US$)
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