Features

Trigonelline is attracting researchers’ interest

Trigonelline: the coffee compound that combats muscle ageing?

11/05/2026

Naturally found in coffee, trigonelline is gaining ground in anti-ageing research. A recent study reveals links with muscle strength and NAD+, a key molecule in cellular metabolism and ageing.

📌︎ Key takeaways

✓Trigonelline is a molecule naturally found in coffee and fenugreek seeds.
✓A recent study found that blood levels of trigonelline are lower in people with sarcopenia (a progressive, generalised loss of muscle mass, strength and function associated with ageing).
✓Higher levels of trigonelline have been linked to improved muscle strength.
✓Experiments on cells and animals suggest that trigonelline may play a role in the production of NAD+.
✓These promising results have yet to be confirmed in humans.

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Features Tiredness

Vitamin B12 reference ranges: how to interpret your blood test results?

Vitamin B12, or cobalamin, contributes to cell division and the functioning of the nervous system. With changing dietary habits, monitoring your B12 status is becoming essential. But how do you interpret your blood test results?

📌︎ Key points

✓Vitamin B12 contributes, amongst other things, to the normal functioning of the nervous system, the normal formation of red blood cells and the process of cell division.
✓A level below 180 pg/mL may indicate a vitamin B12 deficiency, whilst a level between 180 and 350 pg/mL may suggest a possible deficiency.
✓Holotranscobalamin, methylmalonic acid (MMA) and homocysteine can supplement the blood test when the results are unclear.
✓Vegetarians, vegans, older people and those with malabsorption disorders are at greater risk of vitamin B12 deficiency.
✓Foods of animal origin are the primary source of B12. Supplementation tailored to individual needs may be considered where intake is insufficient or in certain high-risk situations.

11/04/2026

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Features Immunity

Lactoferrin: a clinical trial puts immune cells to the test

Naturally present in milk and certain secretions, lactoferrin has intrigued researchers. A new trial investigated how the immune cells of adults over 50 reacted to viruses following supplementation.

📌︎ Key takeaways

✓A clinical trial compared two doses of bovine lactoferrin in 103 adults aged over 50.
✓After four weeks, the researchers analysed the response of their immune cells when exposed to viruses in the laboratory.
✓Several immune markers and cell populations showed different changes depending on the dose administered.
✓The participants were never infected: only their immune cells were studied ex vivo.
✓This study provides new insights into the immune responses observed following supplementation, without demonstrating protection against infections.

10/27/2026

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Features Heart & Circulation

High blood pressure: a clinical study evaluates olive leaf extract

Traditionally associated with cardiovascular health, the olive leaf is the subject of clinical research. A new study involving 621 patients with high blood pressure assesses the effects of olive leaf extract on blood pressure.

📌︎ Key takeaways

✓A randomised, placebo-controlled trial assessed olive leaf extract in 621 patients already being treated for high blood pressure, over a 12-week period.
✓Blood pressure was measured over a 24-hour period, both during the day and at night.
✓Mean systolic blood pressure fell by 6.4 mmHg with the extract, compared with 1.5 mmHg with the placebo.
✓These results add to our understanding, but need to be confirmed.
✓A supplement is not a substitute for antihypertensive treatment. Seek advice before taking any supplements and never alter your treatment without medical advice.

10/21/2026

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Features Vision & Hearing

AMD: a large-scale study explores an unexpected role for melatonin

Best known for its role in the sleep-wake cycle, melatonin may also affect eyesight. A large-scale study of medical records has recently revealed an unexpected association between regular melatonin intake and a reduced risk of developing AMD.

📌︎ Key takeaways

✓A large-scale US study investigated the link between melatonin and age-related macular degeneration (AMD) using data from over 180,000 medical records.
✓Regular use of melatonin was associated with a lower risk of developing AMD.
✓In people already living with dry AMD, it was also associated with a lower risk of progression to exudative AMD.
✓This observational study provides promising scientific evidence, but does not allow us to conclude that there is a cause-and-effect relationship.
✓Melatonin is no substitute for regular eye check-ups or prescribed treatments, but it represents an interesting avenue of research into retinal ageing.

10/14/2026

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Features Tiredness

Dietary supplements and seasonality: the annual supplementation calendar

Changes in light, temperature, diet or lifestyle… Your body doesn’t cope with every season in the same way. Find out how to adapt your dietary supplements wisely throughout the year.

📌︎ Key takeaways

✓Seasonal changes influence certain physiological parameters, particularly circadian rhythms and vitamin D levels.
✓In spring, the focus can be on vitality, liver support and defences against seasonal allergens.
✓In summer, antioxidants and flavonoids help manage sun exposure, whilst melatonin can occasionally help you fall asleep.
✓In autumn, probiotics, zinc and vitamin C help prepare the body nutritionally for the colder months.
✓In winter, reduced exposure to UV light very often calls for vitamin D supplementation.

10/06/2026

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Features Gastrointestinal health

Probiotics and the gut: understanding and optimising your microbiota

Probiotics and the gut have a complex relationship. Far from being simply ‘good bacteria’, these microorganisms interact with a unique ecosystem: the microbiota. Find out how to better understand and maintain it.

📌︎ Key takeaways

✓The gut microbiota comprises between 1,000 and 100,000 billion microorganisms, mainly concentrated in the colon.
✓Probiotics do not establish a long-term presence in the gut, which is why it is beneficial to take them regularly or repeat courses as needed.
✓The properties of probiotics depend closely on the strains used.
✓CFU dosage, freeze-drying and gastro-resistant coating are key criteria for choosing the right supplement.
✓Prebiotics, such as inulin and FOS, act as ‘food’ for certain gut bacteria and optimise their colonisation and activity.

10/01/2026

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Features Joints

Osteoarthritis of the hands: a clinical trial tests the turmeric-boswellia combination

Osteoarthritis of the hands can make many everyday tasks difficult. Whilst studies on plant extracts have mainly focused on the knee, a new clinical trial is investigating the potential effects of the turmeric-boswellia combination on osteoarthritis of the hands.

📌︎ Key takeaways

✓ A clinical study evaluated a combination of turmeric and boswellia in 162 people with symptomatic osteoarthritis of the hands.
✓After three months, the reduction in self-reported pain was greater with the study formula than with the placebo.
✓The trial focused on symptoms and did not assess any changes to the cartilage or the disease itself.
✓There are various turmeric and boswellia-based supplement formulations available.
✓Dietary supplements are not a substitute for medical management of osteoarthritis.

09/30/2026

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Features Vision & Hearing

Blueberries: a boon for eye health?

Eye strain, screens, ageing… Blueberries are attracting increasing interest for their potential effects on vision. But what does the science actually say about their link to eye health?

09/25/2026

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Features Menopause

Best probiotic for the menopause: which one should you choose?

The menopause is accompanied by numerous hormonal changes that also affect the gut and vaginal microbiota. Certain probiotic strains may therefore help to maintain this balance. But which ones?

✦ Key takeaways

✓Menopause profoundly alters the gut and vaginal microbiota.
✓Certain strains of Lactobacillus are the subject of particular research.
✓A recent meta-analysis of 39 studies suggests potential benefits for several menopausal symptoms.
✓Probiotics are not a substitute for comprehensive management.
✓Diet, fibre and certain supplements can help women cope better during this period.

09/23/2026

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Features

Trigonelline: the coffee compound that combats muscle ageing?

Vitamin B12 reference ranges: how to interpret your blood test results?

Lactoferrin: a clinical trial puts immune cells to the test

High blood pressure: a clinical study evaluates olive leaf extract

AMD: a large-scale study explores an unexpected role for melatonin

Dietary supplements and seasonality: the annual supplementation calendar

Probiotics and the gut: understanding and optimising your microbiota

Osteoarthritis of the hands: a clinical trial tests the turmeric-boswellia combination

Blueberries: a boon for eye health?

Best probiotic for the menopause: which one should you choose?

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