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High blood pressure: a clinical study evaluates olive leaf extract

10/21/2026

Traditionally associated with cardiovascular health, the olive leaf is the subject of clinical research. A new study involving 621 patients with high blood pressure assesses the effects of olive leaf extract on blood pressure.

📌︎ Key takeaways
  • ✓A randomised, placebo-controlled trial assessed olive leaf extract in 621 patients already being treated for high blood pressure, over a 12-week period.
  • ✓Blood pressure was measured over a 24-hour period, both during the day and at night.
  • ✓Mean systolic blood pressure fell by 6.4 mmHg with the extract, compared with 1.5 mmHg with the placebo.
  • ✓These results add to our understanding, but need to be confirmed.
  • ✓A supplement is not a substitute for antihypertensive treatment. Seek advice before taking any supplements and never alter your treatment without medical advice.

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Features

AMD: a large-scale study explores an unexpected role for melatonin

Best known for its role in the sleep-wake cycle, melatonin may also affect eyesight. A large-scale study of medical records has recently revealed an unexpected association between regular melatonin intake and a reduced risk of developing AMD.

📌︎ Key takeaways
  • ✓A large-scale US study investigated the link between melatonin and age-related macular degeneration (AMD) using data from over 180,000 medical records.
  • ✓Regular use of melatonin was associated with a lower risk of developing AMD.
  • ✓In people already living with dry AMD, it was also associated with a lower risk of progression to exudative AMD.
  • ✓This observational study provides promising scientific evidence, but does not allow us to conclude that there is a cause-and-effect relationship.
  • ✓Melatonin is no substitute for regular eye check-ups or prescribed treatments, but it represents an interesting avenue of research into retinal ageing.

10/14/2026

Probiotics and the gut: understanding and optimising your microbiota

Probiotics and the gut have a complex relationship. Far from being simply ‘good bacteria’, these microorganisms interact with a unique ecosystem: the microbiota. Find out how to better understand and maintain it.

📌︎ Key takeaways
  • ✓The gut microbiota comprises between 1,000 and 100,000 billion microorganisms, mainly concentrated in the colon.
  • ✓Probiotics do not establish a long-term presence in the gut, which is why it is beneficial to take them regularly or repeat courses as needed.
  • ✓The properties of probiotics depend closely on the strains used.
  • ✓CFU dosage, freeze-drying and gastro-resistant coating are key criteria for choosing the right supplement.
  • ✓Prebiotics, such as inulin and FOS, act as ‘food’ for certain gut bacteria and optimise their colonisation and activity.

10/01/2026

Osteoarthritis of the hands: a clinical trial tests the turmeric-boswellia combination

Osteoarthritis of the hands can make many everyday tasks difficult. Whilst studies on plant extracts have mainly focused on the knee, a new clinical trial is investigating the potential effects of the turmeric-boswellia combination on osteoarthritis of the hands.

📌︎ Key takeaways
  • ✓ A clinical study evaluated a combination of turmeric and boswellia in 162 people with symptomatic osteoarthritis of the hands.
  • ✓After three months, the reduction in self-reported pain was greater with the study formula than with the placebo.
  • ✓The trial focused on symptoms and did not assess any changes to the cartilage or the disease itself.
  • ✓There are various turmeric and boswellia-based supplement formulations available.
  • ✓Dietary supplements are not a substitute for medical management of osteoarthritis.

09/30/2026
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